Browsing HV - Institutt for naturvitenskapelige helsefag by Title
Now showing items 258-277 of 407
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Patterns of aggressiveness: Risk of progression to invasive breast cancer by mammographic features of calcifications in screen-detected ductal carcinoma in situ
(Peer reviewed; Journal article, 2021)Background Mammographic features of calcifications on mammograms showing invasive breast cancer are associated with survival. Less is known about mammographic features and progression to invasive breast cancer among women ... -
Patterns of local-regional recurrence after conformal and intensity-modulated radiotherapy for head and neck cancer
(Journal article; Peer reviewed, 2017)Aim To evaluate the patterns of loco-regional recurrences in head and neck cancer patients Methods Twenty-six out of 112 patients treated with primary or postoperative 3D CRT or IMRT for their primary and recurrent ... -
Personality traits and the risk of becominglonely in old age: A 5-year follow-up study
(Health and Quality of Life Outcomes;18, Article number: 47 (2020), Journal article; Peer reviewed, 2020-02-20)Background: Although many people experience loneliness in old age, there is little knowledge of predisposing personality factors. The aim of the present study was to explore to what extent personality traits are associated ... -
Pharmacists’ experience of a diabetes risk-assessment service and analytical quality control in community pharmacies : a focus-group study
(Research in Social and Administrative Pharmacy;, Journal article; Peer reviewed, 2020-09-19)Background: Healthcare services such as diabetes risk-assessment are increasingly common in community pharmacies. Knowledge of community pharmacists’ experiences of such services could ease the implementation of a larger-scale ... -
Pharmacokinetic variability and clinical use of lacosamide in children and adolescents in Denmark and Norway
(Therapeutic Drug Monitoring;41 (3): 340–347, JUNE 2019, Journal article; Peer reviewed, 2019-01-01)Background: The indication for the antiepileptic drug (AED) lacosamide (LCM) was recently extended to include children from the age of four. Real-life data on the use and serum concentrations of LCM in children and ... -
Pharmacokinetic variability of everolimus and impact of concomitant antiseizure medications in patients with tuberous sclerosis complex: A retrospective study of therapeutic drug monitoring data in Denmark and Norway
(Peer reviewed; Journal article, 2024)The mTOR-inhibitor everolimus is a precision drug with antiepileptogenic properties approved for treatment of epilepsy in persons with tuberous sclerosis complex (TSC) in combination with other antiseizure medications ... -
Pharmacological aspects of antiseizure medications: From basic mechanisms to clinical considerations of drug interactions and use of therapeutic drug monitoring
(Journal article; Peer reviewed, 2023)Antiseizure medications (ASMs) are the cornerstone of treatment for patients with epilepsy. Several new ASMs have recently been introduced to the market, making it possible to better tailor the treatment of epilepsy, as ... -
Pharmacology and drug interactions of cannabinoids
(Epileptic Disorders;Vol. 22, Supplement 1, Journal article; Peer reviewed, 2020)Cannabinoids include a variety of substances, of which cannabidiol (CBD) is the main substance investigated for the treatment of epilepsy, and this will be the focus in the present review. CBD preparations exist in various ... -
Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users
(Breast Cancer Research;14 (R135), Journal article; Peer reviewed, 2012-10-27)Introduction Mammographic density (MD) is one of the strongest known breast cancer risk factors. Estrogen and progestin therapy (EPT) has been associated with increases in MD. Dense breast tissue is characterized by ... -
PopAffiliator: online calculator for individual affiliation to a major population group based on 17 autosomal short tandem repeat genotype profile.
(International journal of legal medicine;124, Journal article; Peer reviewed, 2010-06-16)Because of their sensitivity and high level of discrimination, short tandem repeat (STR) maker systems are currently the method of choice in routine forensic casework and data banking, usually in multiplexes up to 15–17 ... -
A population study of Norwegian psychiatric patients referred for clinical brain scanning
(BJPsych Open;Volume 4, Issue 3, Journal article; Peer reviewed, 2018-05-08)Background Patients with psychiatric conditions are often referred for a brain scan during the course of their diagnostic workup. Aims The aim of our study is to determine frequency and type of organic brain pathology, ... -
Positioning of community pharmacists in interactions with general practitioners and patients regarding prescribing and using antibiotics
(Journal of Interprofessional Care;, Peer reviewed; Journal article, 2023)Interprofessional collaboration between general practitioners (GPs) and community pharmacists (CPs) is important for ensuring antibiotics are used correctly and combating antibiotic resistance. The study’s main objective ... -
Praksisstudienes omfang og organisering i bioingeniørutdanningen
(Peer reviewed; Journal article, 2022)Siden 2005 har omfang og innhold i bioingeniørutdanningen vært definert av en nasjonal rammeplan for å sikre likeverdig sluttkompetanse for alle kandidater. Fra 2019 ble en ny forskrift om nasjonale retningslinjer ... -
Praksisstudienes omfang og organisering i bioingeniørutdanningen
(Peer reviewed; Journal article, 2022)Siden 2005 har omfang og innhold i bioingeniørutdanningen vært definert av en nasjonal rammeplan for å sikre likeverdig sluttkompetanse for alle kandidater. Fra 2019 ble en ny forskrift om nasjonale retningslinjer fastsatt. ... -
Pre-cementation procedures' effect on dental zirconias with different yttria content
(Dental Materials;Volume 37, Issue 9, Peer reviewed; Journal article, 2021-07-28)Objective: Several pre-cementation procedures have been advocated to enhance adhesion between zirconia and resin-based cement. There is, however, limited documentation on how these pre-treatments affect the strength of ... -
Pre-dosing with lilotomab prior to therapy with 177Lu-lilotomab satetraxetan significantly increases the ratio of tumor to red marrow absorbed dose in non-Hodgkin lymphoma patients
(European Journal of Nuclear Medicine and Molecular Imaging;July 2018, Volume 45, Issue 7, Journal article; Peer reviewed, 2018-02-22)Purpose: 177Lu-lilotomab satetraxetan is a novel anti-CD37 antibody radionuclide conjugate for the treatment of non-Hodgkin lymphoma (NHL). Four arms with different combinations of pre-dosing and pre-treatment have been ... -
Pre-stroke cognitive impairment is associated with vascular imaging pathology: a prospective observational study
(BMC Geriatrics;21, Article number: 362 (2021), Peer reviewed; Journal article, 2021-06-14)Background: Chronic brain pathology and pre-stroke cognitive impairment (PCI) is predictive of post-stroke dementia. The aim of the current study was to measure pre-stroke neurodegenerative and vascular disease burden found ... -
Prediction of Age Older than 18 Years in Sub-adults by MRI Segmentation of 1st and 2nd Molars
(Journal article; Peer reviewed, 2023)Purpose To investigate prediction of age older than 18 years in sub-adults using tooth tissue volumes from MRI segmenta- tion of the entire 1st and 2nd molars, and to establish a model for combining information from two ... -
Prediction of CYP2D6 poor metabolizers by measurements of solanidine and metabolites—a study in 839 patients with known CYP2D6 genotype
(Peer reviewed; Journal article, 2023)Purpose Poor metabolizers (PMs) of the highly polymorphic enzyme CYP2D6 are usually at high risk of adverse effects during standard recommended dosing of CYP2D6-metabolized drugs. We studied if the metabolism of solanidine, ... -
A preliminary study of the use of MinION sequencing to specifcally detect Shiga toxin‑producing Escherichia coli in culture swipes containing multiple serovars of this species
(Peer reviewed; Journal article, 2023)An important challenge relating to clinical diagnostics of the foodborne pathogen Shiga toxin-producing E. coli (STEC), is that PCR-detection of the shiga-toxin gene (stx) in DNA from stool samples can be accompanied by a ...