Recent Submissions

  • Changes in the use of antiseizure medications in children and adolescents in Norway, 2009–2018 

    Heger, Katrine; Skipsfjord, Julia; Kiselev, Yury; Burns, Margrete Larsen; Aaberg, Kari Modalsli; Johannessen, Svein Ivar; Skurtveit, Svetlana Ondrasova; Landmark, Cecilie Johannessen (Epilepsy Research;Volume 181, March 2022, 106872, Peer reviewed; Journal article, 2022-02-15)
    Background: The use of antiseizure medications (ASMs) in the pediatric population is poorly studied. The purpose of this study was to investigate changes in the use of ASMs in children and adolescents compared to adults, ...
  • Hemoglobinopathy gone astray—three novel forms of α-thalassemia in Norwegian patients characterized by quantitative real-time PCR and DNA sequencing 

    Grimholt, Runa Marie; Fjeld, Bente; Klingenberg, Olav (Scandinavian Journal of Clinical and Laboratory Investigation;Volume 81, 2021 - Issue 8, Peer reviewed; Journal article, 2021-11-18)
    α-thalassemia is one of the most common monogenic diseases worldwide and is caused by reduced or absent synthesis of α-globin chains, most commonly due to deletions of one or more of the α-globin genes. α-thalassemia occurs ...
  • Prosigna Gene Signature to Assess Expected Benefit from Chemotherapy in Breast Cancer. Assessment of manufacturer’s submission 

    Kvist, Beate Charlotte Fagerlund; Chudasama, Kishan Kumar; Brurberg, Kjetil Gundro; Robberstad, Bjarne; Rose, Christopher James; Juvet, Lene Kristine; Fretheim, Atle (Book; Peer reviewed; Research report, 2019-08-16)
    Breast cancer can be treated with chemotherapy, hormone therapy and radiation, or a combination of these to prevent the spread of cancer cells, after surgical removal of the tumor. When assessing whether a patient should ...
  • Medication dose calculation errors and other numeracy mishaps in hospitals: Analysis of the nature and enablers of incident reports 

    Mulac, Alma; Hagesæther, Ellen; Granås, Anne Gerd (Journal of Advanced Nursing;Volume 78, Issue 1, Peer reviewed; Journal article, 2021-10-10)
    Aims: To investigate medication dose calculation errors and other numeracy mishaps in hospitals and examine mechanisms and enablers which lead to such errors. Design: A retrospective study using descriptive statistics ...
  • The Bridge Building Model: connecting evidence-based practice, evidence-based research, public involvement and needs led research 

    Ormstad, Heidi; Jamtvedt, Gro; Svege, Ida; Crowe, Sally (Research Involvement and Engagement;7, Article number: 77 (2021), Peer reviewed; Journal article, 2021-10-30)
    This paper describes a model that combines different concepts in healthcare research that the authors suggest belong together. The concepts are; Evidence Based Practice, where healthcare is based on the best research ...
  • Artificial intelligence in the fertility clinic: status, pitfalls and possibilities 

    Riegler, Michael Alexander; Stensen, Mette Haug; Witczak, Oliwia; Andersen, Jorunn Marie; Hicks, Steven; Hammer, Hugo Lewi; Delbarre, Erwan; Halvorsen, Pål; Yazidi, Anis; Holst, Nicolai; Haugen, Trine B. (Human Reproduction;Volume 36, Issue 9, Peer reviewed; Journal article, 2021-07-29)
    In recent years, the amount of data produced in the field of assisted reproduction technology [ART] has increased exponentially. The diversity of data is large, ranging from videos to tabular data. At the same time, ...
  • Self-collected and clinician-collected anal swabs show modest agreement for HPV genotyping 

    Mandishora, Racheal S. Dube; Rounge, Trine Ballestad; Fitzpatrick, Megan; Christiansen, Hanne Irene Kraus; Ambur, Ole Herman; Lagström, Sonja; Stray-Pedersen, Babill; Tommasino, Massimo; Palefsky, Joel; Chirenje, Zvavahera M. (PLOS ONE;16 (4): e0250426, Peer reviewed; Journal article, 2021-04-26)
    Background & aim: Women with HIV/HPV coinfection and cervical lesions are at increased risk of developing HPV related anal cancer. Self-collection of anal swabs may facilitate HPV molecular testing in anal cancer screening, ...
  • Characterization of miRNAs in Embryonic, Larval, and Adult Lumpfish Provides a Reference miRNAome for Cyclopterus lumpus 

    Chakraborty, Setu; Woldemariam, Nardos Tesfaye; Visnovska, Tina; Rise, Matthew L.; Santander, Javier; Andreassen, Rune (Biology;Volume 11 / Issue 1, Peer reviewed; Journal article, 2022-01-13)
    MicroRNAs (miRNAs) are endogenous small RNA molecules involved in the post-transcriptional regulation of protein expression by binding to the mRNA of target genes. They are key regulators in teleost development, maintenance ...
  • HPV16 and HPV18 type-specific APOBEC3 and integration profiles in different diagnostic categories of cervical samples 

    Lagström, Sonja; Løvstad, Alexander H; Umu, Sinan Uğur; Ambur, Ole Herman; Nygård, Mari; Rounge, Trine Ballestad; Christiansen, Irene Kraus (Tumour Virus Research;Volume 12, December 2021, 200221, Peer reviewed; Journal article, 2021-07-14)
    Human papillomavirus (HPV) 16 and 18 are the most predominant types in cervical cancer. Only a small fraction of HPV infections progress to cancer, indicating that additional factors and genomic events contribute to the ...
  • Lamotrigine effects on immune gene expression in larval zebrafish 

    Mochol, Monika; Whatmore, Paul; Taubøll, Erik; Landmark, Cecilie Johannessen; Ropstad, Erik; Svalheim, Sigrid; Fraser, Thomas (Epilepsy Research;Volume 178, December 2021, 106823, Peer reviewed; Journal article, 2021-11-26)
    Purpose: Despite growing evidence that neuroinflammation and pro-inflammatory cytokines are involved in the pathogenesis of seizures and epilepsy, this knowledge has not been incorporated in the proposed mechanism of action ...
  • Measuring Staff Attitudes to Coercion in Poland 

    Lickiewicz, Jakub; Husum, Tonje Lossius; Ruud, Torleif; Siqveland, Johan; Musiał, Zofia; Makara-Studzińska, Marta (Frontiers in Psychiatry;November 2021 | Volume 12 | Article 745215, Peer reviewed; Journal article, 2021-11-16)
    Introduction: Coercion can be defined as the use of force to limit a person’s choices. In Poland, coercive measures may tend to be overused. However, there is limited information regarding the attitudes of nurses toward ...
  • Severe and fatal medication errors in hospitals: findings from the Norwegian Incident Reporting System 

    Mulac, Alma; Taxis, Katja; Hagesæther, Ellen; Granås, Anne Gerd (European Journal of Hospital Pharmacy (EJHP);Volume 28, Issue e1, Peer reviewed; Journal article, 2020-06-23)
    Background: Even with global efforts to prevent medication errors, they still occur and cause patient harm. Little systematic research has been done in Norway to address this issue. Objectives: To describe the frequency, ...
  • Mechanical-stress-related epigenetic regulation of ZIC1 transcription factor in the etiology of postmenopausal osteoporosis 

    Datta, Harish K.; Kringen, Marianne K.; Tuck, Stephen P.; Salpingidou, Georgia; Olstad, Ole K.; Gautvik, Kaare M; Cockell, Simon; Gautvik, Vigdis Teig; Prediger, Michael; Wu, Jun J.; Birch, Mark A.; Reppe, Sjur (Peer reviewed; Journal article, 2022)
    Mechanical loading exerts a profound influence on bone density and architecture, but the exact mechanism is unknown. Our study shows that expression of the neurological transcriptional factor zinc finger of the cerebellum ...
  • Contrast medium protocols in routine chest CT:a survey study 

    Henning, Mette Karen; Aaløkken, Trond M; Johansen, Safora (Peer reviewed; Journal article, 2021)
    Background Administration of contrast medium (CM) is an important image quality factor in computed tomography (CT) of the chest. There is no clear evidence or guidelines on CM strategies for chest CT, thus a consensus ...
  • Measuring Staff Attitudes to Coercion in Poland 

    Lickiewicz, Jakub; Husum, Tonje Lossius; Ruud, Torleif; Siqveland, Johan; Musiał, Zofia; Makara-Studzińska, Marta (Frontiers in Psychiatry;November 2021 | Volume 12 | Article 745215, Peer reviewed; Journal article, 2021-11-16)
    Introduction: Coercion can be defined as the use of force to limit a person’s choices. In Poland, coercive measures may tend to be overused. However, there is limited information regarding the attitudes of nurses toward ...
  • Effect and tolerability of perampanel in patients with drug-resistant epilepsy 

    Lossius, Ida Marie Bakke; Svendsen, Torleiv; Sødal, Hild Flatmark; Kjeldstadli, Kari Grandaunet; Lossius, Morten Ingvar; Nakken, Karl Otto; Landmark, Cecilie Johannessen (Epilepsy & Behavior;Volume 119, June 2021, 107965, Peer reviewed; Journal article, 2021-04-30)
    Objective: Perampanel is one of the most recently approved antiseizure medications. The aim of the present study was to assess clinical efficacy and tolerability, in combination with pharmacokinetic variability, of perampanel ...
  • Determinants of knowledge and attitude towards breastfeeding in rural pregnant women using validated instruments in Ethiopia 

    Ahmed, Misra Abdulahi; Fretheim, Atle; Argaw, Alemayehu; Magnus, Jeanette H. (International Journal of Environmental Research and Public Health (IJERPH);Volume 18 / Issue 15, Peer reviewed; Journal article, 2021-07-27)
    Understanding the underlying determinants of maternal knowledge and attitude towards breastfeeding guides the development of context-specific interventions to improve breastfeeding practices. This study aimed to assess the ...
  • Patterns of aggressiveness: Risk of progression to invasive breast cancer by mammographic features of calcifications in screen-detected ductal carcinoma in situ 

    Lilleborge, Marie; Falk, Ragnhild Sørum; Hovda, Tone; Holmen, Marit Muri; Ursin, Giske; Hofvind, Solveig (Peer reviewed; Journal article, 2021)
    Background Mammographic features of calcifications on mammograms showing invasive breast cancer are associated with survival. Less is known about mammographic features and progression to invasive breast cancer among women ...
  • Studentaktiv læring i praksisrettet undervisning for radiografstudenter 

    Hammerstrøm, Linda; Strømme Johannesen, Tone (Radiography Open;Vol. 7 No. 1 (2021), Peer reviewed; Journal article, 2021-12-13)
    In radiography education, providing the students the means to combine theoretical knowledge with practical skills is crucial in preparation for placements in imaging departments. Previous and ongoing research supports that ...
  • Iterative reconstruction improves image quality and reduces radiation dose in trauma protocols; A human cadaver study 

    Godt, Johannes Jakob Clemens; Johansen, Cathrine K.; Martinsen, Anne Catrine Trægde; Schulz, Anselm; Brøgger, Helga Maria; Jensen, Kristin; Stray-Pedersen, Arne; Dormagen, Johann Baptist (Acta Radiologica Open;Volume: 10, issue: 10, Peer reviewed; Journal article, 2021-11-18)
    Background: Radiation-related cancer risk is an object of concern in CT of trauma patients, as these represent a young population. Different radiation reducing methods, including iterative reconstruction (IR), and spilt ...

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