HV - Institutt for naturvitenskapelige helsefag
Recent Submissions
-
Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6-catalyzed metabolism of solanidine
(Peer reviewed; Journal article, 2024)Cytochrome P450 2D6 (CYP2D6) is important for metabolism of 20%–25% of all clinically used drugs. Many known genetic variants contribute to the large interindividual variability in CYP2D6 metabolism, but much is still ... -
The choice of diagnostic modality influences the proportion of low muscle strength, low muscle mass, and sarcopenia in colorectal cancer patients
(Peer reviewed; Journal article, 2024)Background and aims: Low muscle strength, low muscle mass, and sarcopenia have a negative impact on health outcomes in colorectal cancer (CRC) patients. Different diagnostic modalities are used to identify these conditions ... -
The Battle of the Equations: A Systematic Review of Jump Height Calculations Using Force Platforms
(Peer reviewed; Journal article, 2024)Vertical jump height measures our ability to oppose gravity and lower body neuromuscular function in athletes and various clinical populations. Vertical jump tests are principally simple, time-efficient, and extensively ... -
Pharmacist supply of non-prescription sildenafil in Norway: a simulated patient mixed-method study
(International Journal of Pharmacy Practice (IJPP);, Peer reviewed; Journal article, 2024)Background: Pharmacist supply of non-prescription sildenafil was initiated in Norway in 2019, and continuous evaluation of the service is warranted. Objectives: To map how the service checklist is used, to evaluate the ... -
Hallmarks of primary headache: part 1 – migraine
(Peer reviewed; Journal article, 2024)Background and aim Migraine is a common disabling conditions which, globally, affects 15.2% of the population. It is the second cause of health loss in terms of years lived with disability, the first among women. Despite ... -
Whole genome sequencing and characterization of Corynebacterium isolated from the healthy and dry eye ocular surface
(BMC Microbiology;, Peer reviewed; Journal article, 2024)Background: The purpose of this study was to characterize Corynebacterium isolated from the ocular surface of dry eye disease patients and healthy controls. We aimed to investigate the pathogenic potential of these isolates ... -
Virtual reality as a method of cognitive training of processing speed, working memory, and sustained attention in persons with acquired brain injury: a protocol for a randomized controlled trial
(Peer reviewed; Journal article, 2024)Background Acquired brain injury (ABI) often leads to persisting somatic, cognitive, and social impairments. Cognitive impairments of processing speed, sustained attention, and working memory are frequently reported and ... -
Novel Teixobactin Analogues Show Promising In Vitro Activity on Biofilm Formation by Staphylococcus aureus and Enterococcus faecalis
(Current Microbiology;, Peer reviewed; Journal article, 2024)The treatment of infections caused by biofilm-forming organisms is challenging. The newly discovered antibiotic teixobactin shows activity against a wide range of biofilm-forming bacteria. However, the laborious and low-yield ... -
Identification of required capabilities of digital health ecosystems when preventing and managing non-communicable diseases
(Digital Health;, Peer reviewed; Journal article, 2024)Objective: Non-communicable diseases cause annual mortality for 41 million people worldwide. These diseases include coronary heart disease, cancer, stroke, diabetes, and musculoskeletal as well as mental disorders. Innovation ... -
Genomics of Staphylococcus aureus and Enterococcus faecalis isolated from the ocular surface of dry eye disease sufferers
(Peer reviewed; Journal article, 2024)Ocular surface inflammatory disorders, such as dry eye, are becoming increasingly prevalent. Developing new treatment strategies targeting harmful bacteria could provide significant therapeutic benefits. The purpose of ... -
Changes in intrahost genetic diversity according to lesion severity in longitudinal HPV16 samples
(Peer reviewed; Journal article, 2024)Human papillomavirus type 16 (HPV16) is the most common cause of cervical cancer, but most infections are transient with lesions not progressing to cancer. There is a lack of specific biomarkers for early cancer risk ... -
Does in vitro hemolysis affect measurements of plasma apixaban concentration by UPLC-MS and anti-Xa assay?
(Peer reviewed; Journal article, 2024)Introduction: Hemolytic interference may impact various laboratory tests, including coagulation analyses. Apixaban is the most commonly used direct oral anticoagulant in Norway, and there is lacking knowledge on how ... -
Technologically advanced running shoes reduce oxygen cost and cumulative tibial loading per kilometer in recreational female and male runners
(Peer reviewed; Journal article, 2024)Technologically advanced running shoes (TARS) improve performance compared to classical running shoes (CRS). Improved race performance has been attributed to metabolic savings in male runners, but it remains unclear if ... -
Characterization of the impact of dietary immunostimulant CpG on the expression of mRNA biomarkers involved in the immune responses in Atlantic salmon (Salmo salar)
(Peer reviewed; Journal article, 2024)Infectious diseases have significantly impacted Atlantic salmon aquaculture worldwide. Modulating fish immunity with immunostimulant-containing functional feeds could be an effective strategy in mitigating disease problems. ... -
Fenfluramine treatment in pediatric patients with Dravet syndrome reduces seizure burden and overall healthcare costs: A retrospective and observational real-world study
(Epilepsia Open;, Peer reviewed; Journal article, 2024)Objectives: Dravet syndrome is a developmental and epileptic encephalopathy characterized by early onset epilepsy with multiple seizure types often intractable to treatment. Randomized clinical trials have demonstrated how ... -
Pharmacokinetic variability of everolimus and impact of concomitant antiseizure medications in patients with tuberous sclerosis complex: A retrospective study of therapeutic drug monitoring data in Denmark and Norway
(Peer reviewed; Journal article, 2024)The mTOR-inhibitor everolimus is a precision drug with antiepileptogenic properties approved for treatment of epilepsy in persons with tuberous sclerosis complex (TSC) in combination with other antiseizure medications ... -
Social Media Use and Consumption of Prescription-Free Medications for Anxiety, Sleep, and Pain among Norwegian University Students
(European Journal of Investigation in Health, Psychology and Education;, Peer reviewed; Journal article, 2024)A relationship has been recognized between social media use and health issues. However, no studies have explored the potential link between social media use and consumption of over-the-counter (OTC) medications. We examined ... -
Comparative Effectiveness and Persistence of SB4 and Reference Etanercept in Patients With Psoriatic Arthritis in Norway
(Arthritis care & research;, Peer reviewed; Journal article, 2024)Objective. We aim to compare drug effectiveness and persistence between the reference etanercept (ETN) and ETN biosimilar SB4 in patients with psoriatic arthritis (PsA) naive to ETN and to investigate drug effectiveness ... -
Evaluation of an in-use chest CT protocol in lung cancer screening - A single institutional study
(Acta Radiologica Open;, Peer reviewed; Journal article, 2024)Background: Lung cancer is the most common cause of cancer-related death worldwide and therefore there has been a growing demand for low-dose computed tomography (LDCT) protocols. Purpose: To investigate and evaluate ... -
Lung cancer reirradiation: Exploring modifications to utilization, treatment modalities and factors associated with outcomes
(Peer reviewed; Journal article, 2024)ABSTRACT Background: Patients treated for lung cancer (LC) often experience locoregional failure after initial treatment. Due to technological ad- vances, thoracic reirradiation (re-RT) has become a viable treatment option. ...
RSS 2.0