HV - Institutt for naturvitenskapelige helsefag
Recent Submissions
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Detection of colorectal-cancer-associated bacterial taxa in fecal samples using next-generation sequencing and 19 newly established qPCR assays
(Peer reviewed; Journal article, 2024)We have previously identified increased levels of distinct bacterial taxa within mucosal biopsies from colorectal cancer (CRC) patients. Following prior research, the aim of this study was to investigate the detection of ... -
Decoding immune-related gene-signatures in colorectal neoplasia
(Peer reviewed; Journal article, 2024)Background: Colorectal cancer (CRC) is a significant health issue, with notable incidence rates in Norway. The immune response plays a dual role in CRC, offering both protective effects and promoting tumor growth. This ... -
Quality of referrals for lower extremity ultrasonography and computed tomography pulmonary angiography and associations with positive findings of venous thromboembolism
(Peer reviewed; Journal article, 2024)Introduction: The referral is the basis for radiologists’ assessment of modality, protocol and urgency, and insufficient information may threaten patient safety. The aim of this study was to assess the completeness of ... -
The impact of surface charge on the interaction of cholesterol-free fusogenic liposomes with planktonic microbial cells and biofilms
(Peer reviewed; Journal article, 2025)This study focused on the development of cholesterol-free fusogenic liposomes with different surface charge with the aim of improving biofilm penetration. In vitro assessments of the liposomes included physical ... -
A Complete Globe Dislocation without Orbital Wall Fracture
(Case Reports in Ophthalmology;, Peer reviewed; Journal article, 2024)Introduction: The complete globe dislocation is a rare type of trauma in clinical practice of ophthalmologists. Case Presentation: In this report, we present a case of complete globe dislocation with optic nerve avulsion ... -
Success factors for interventions to reduce low-value imaging. Six crucial lessons learned from a practical case study in Norway
(Current problems in diagnostic radiology;, Peer reviewed; Journal article, 2024)Background: Substantial overuse of health care services is identified and intensified efforts are incited to reduce low-value services in general and in imaging in particular. Objective: To report crucial success factors ... -
Academic Detailing is a Preferred Knowledge Update Tool Among Norwegian Pharmacists to Improve Antibiotic Counseling: Results From a Quantitative Study Employing the Provider Satisfaction With Academic Detailing (PSAD) and the Detailer Assessment of Visit Effectiveness (DAVE) Tools
(Peer reviewed; Journal article, 2024)Excessive and incorrect use of antibiotics contributes to the rise of antimicrobial resistance (AMR). Given that pharmacists act as final checkpoint before antibiotics is handled over to patients, they play a crucial role ... -
Computed tomography for visible haematuria – a single nephrographic phase is sufficient for detecting renal cell carcinoma
(Peer reviewed; Journal article, 2024)Objectives: No previous studies have compared two computed tomography (CT) protocols in patients presenting with visible haematuria, and most patients undergo a multiphase CT in order to detect upper tract malignancies. ... -
A monoallelic UXS1 variant associated with short-limbed short stature
(Peer reviewed; Journal article, 2024)Background: Serine residues in the protein backbone of heavily glycosylated proteoglycans are bound to glycosaminoglycans through a tetrasaccharide linker. UXS1 encodes UDP-glucuronate decarboxylase 1, which catalyzes ... -
Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6-catalyzed metabolism of solanidine
(Peer reviewed; Journal article, 2024)Cytochrome P450 2D6 (CYP2D6) is important for metabolism of 20%–25% of all clinically used drugs. Many known genetic variants contribute to the large interindividual variability in CYP2D6 metabolism, but much is still ... -
The choice of diagnostic modality influences the proportion of low muscle strength, low muscle mass, and sarcopenia in colorectal cancer patients
(Peer reviewed; Journal article, 2024)Background and aims: Low muscle strength, low muscle mass, and sarcopenia have a negative impact on health outcomes in colorectal cancer (CRC) patients. Different diagnostic modalities are used to identify these conditions ... -
The Battle of the Equations: A Systematic Review of Jump Height Calculations Using Force Platforms
(Peer reviewed; Journal article, 2024)Vertical jump height measures our ability to oppose gravity and lower body neuromuscular function in athletes and various clinical populations. Vertical jump tests are principally simple, time-efficient, and extensively ... -
Pharmacist supply of non-prescription sildenafil in Norway: a simulated patient mixed-method study
(International Journal of Pharmacy Practice (IJPP);, Peer reviewed; Journal article, 2024)Background: Pharmacist supply of non-prescription sildenafil was initiated in Norway in 2019, and continuous evaluation of the service is warranted. Objectives: To map how the service checklist is used, to evaluate the ... -
Hallmarks of primary headache: part 1 – migraine
(Peer reviewed; Journal article, 2024)Background and aim Migraine is a common disabling conditions which, globally, affects 15.2% of the population. It is the second cause of health loss in terms of years lived with disability, the first among women. Despite ... -
Whole genome sequencing and characterization of Corynebacterium isolated from the healthy and dry eye ocular surface
(BMC Microbiology;, Peer reviewed; Journal article, 2024)Background: The purpose of this study was to characterize Corynebacterium isolated from the ocular surface of dry eye disease patients and healthy controls. We aimed to investigate the pathogenic potential of these isolates ... -
Virtual reality as a method of cognitive training of processing speed, working memory, and sustained attention in persons with acquired brain injury: a protocol for a randomized controlled trial
(Peer reviewed; Journal article, 2024)Background Acquired brain injury (ABI) often leads to persisting somatic, cognitive, and social impairments. Cognitive impairments of processing speed, sustained attention, and working memory are frequently reported and ... -
Novel Teixobactin Analogues Show Promising In Vitro Activity on Biofilm Formation by Staphylococcus aureus and Enterococcus faecalis
(Current Microbiology;, Peer reviewed; Journal article, 2024)The treatment of infections caused by biofilm-forming organisms is challenging. The newly discovered antibiotic teixobactin shows activity against a wide range of biofilm-forming bacteria. However, the laborious and low-yield ... -
Identification of required capabilities of digital health ecosystems when preventing and managing non-communicable diseases
(Digital Health;, Peer reviewed; Journal article, 2024)Objective: Non-communicable diseases cause annual mortality for 41 million people worldwide. These diseases include coronary heart disease, cancer, stroke, diabetes, and musculoskeletal as well as mental disorders. Innovation ... -
Genomics of Staphylococcus aureus and Enterococcus faecalis isolated from the ocular surface of dry eye disease sufferers
(Peer reviewed; Journal article, 2024)Ocular surface inflammatory disorders, such as dry eye, are becoming increasingly prevalent. Developing new treatment strategies targeting harmful bacteria could provide significant therapeutic benefits. The purpose of ... -
Changes in intrahost genetic diversity according to lesion severity in longitudinal HPV16 samples
(Peer reviewed; Journal article, 2024)Human papillomavirus type 16 (HPV16) is the most common cause of cervical cancer, but most infections are transient with lesions not progressing to cancer. There is a lack of specific biomarkers for early cancer risk ...
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