Recent Submissions

  • Epigenetics of Migraine 

    Gazerani, Parisa (Chapter; Peer reviewed, 2023)
    Genetics and the environment have both been demonstrated to take part in the pathogenesis of migraine. Studying the epigenetic mechanisms underlying migraine can facilitate the understanding of the disorder, its chronification, ...
  • Human Brain Organoids in the Preclinical Phase of Drug Development for Migraine 

    Gazerani, Parisa (Peer reviewed; Journal article, 2024)
    Developing drugs for brain disorders poses significant hurdles. These challenges stem from the scarcity of optimal models for preclinical drug testing and the often observed lack of translation from preclinical to human ...
  • Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients 

    Naqvi, Maria; Fineide, Fredrik; Utheim, Tor Paaske; Charnock, Colin (Peer reviewed; Journal article, 2024)
    Purpose: The purpose of this study was to investigate the ocular microbiome in individuals with dry eye disease and to identify features of their ocular microbiome of possible health and diagnostic significance. Methods: ...
  • Social Prescribing Competence among Community Pharmacists and Pharmacy Students in Norway 

    Gabeyre, Riyaan Mahamud; Hussein, Misbah; Salih, Siedra; Amir, Salia; Gazerani, Parisa (Peer reviewed; Journal article, 2024)
    Background and aim: Social prescribing, which links patients to non-clinical services and involves general physicians, has been gaining traction. Community pharmacists, who are integral to primary healthcare, have untapped ...
  • A Preservative-Free Approach – Effects on Dry Eye Signs and Symptoms After Cataract Surgery 

    Jensen, Per Graae; Nilsen, Christian; Gundersen, Morten; Gundersen, Kjell Gunnar; Potvin, Rick; Gazerani, Parisa; Chen, Xiangjun; Utheim, Tor Paaske; Utheim, Øygunn Aass (Peer reviewed; Journal article, 2024)
    Purpose: To compare the effect of treatment with preservative-free dexamethasone, NSAIDs and trehalose/hyaluronic acid eye drops with the preservative benzalkonium chloride containing dexamethasone and NSAIDs after cataract ...
  • Amplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia 

    Elsaid, Khaled; Merriman, Tony R.; Rossitto, Leigh-Ana; Liu-Bryan, Ru; Karsh, Jacob; Phipps-Green, Amanda; Jay, Gregory D.; Elsayed, Sandy; Qadri, Marwa; Miner, Marin; Cadzow, Murray; Dambruoso, Talia J.; Schmidt, Tannin A.; Dalbeth, Nicola; Chhana, Ashika; Höglund, Jennifer; Ghassemian, Majid; Campeau, Anaamika; Maltez, Nancy; Karlsson, Niclas; Gonzalez, David J.; Terkeltaub, Robert (Journal article; Peer reviewed, 2023)
    Objective. In gout, hyperuricemia promotes urate crystal deposition, which stimulates the NLRP3 inflammasome and interleukin-1β (IL-1β)–mediated arthritis. Incident gout without background hyperuricemia is rarely reported. ...
  • Correlations between 68Ga]Ga-DOTA-TOC Uptake and Absorbed Dose from [177Lu]Lu-DOTA-TATE 

    Bruvoll, Ragnar Bjørn Watte; Blakkisrud, Johan; Mikalsen, Lars Tore Gyland; Connelly, James Pattrick; Stokke, Caroline (Journal article; Peer reviewed, 2023)
    Purpose: The aim of this paper was to investigate correlations between pre- therapeutic [68Ga]Ga-DOTA-TOC uptake and absorbed dose to tumours from therapy with [177Lu]Lu-DOTA- TATE. Methods: This retrospective study included ...
  • Interactions between antiseizure medications and foods and drinks: A systematic review 

    Asadi-Pooya, Ali A.; Landmark, Cecilie Johannessen; Nafiseh Mirzaei, Damabi; Khatereh, Fazelian (Peer reviewed; Journal article, 2024)
    Antiseizure medications (ASMs) constitute the principal of treatment for patients with epilepsy, where long-term treatment is usually necessary. The purpose of this systematic review is to provide practical and useful ...
  • Parental alienation – a valid experience? 

    Meland, Eivind; Furuholmen, Dag; Jahanlu, David (Peer reviewed; Journal article, 2023)
    Background: The phenomenon of ‘parental alienation’ is controversial and little explored in the Nordic countries. We wanted to investigate whether parental alienation is a valid concept and how it is perceived in a Nordic ...
  • Evaluation of the diagnostic performance of three D-dimer assays in patients with suspected deep vein thrombosis: STA-Liatest D-Di plus, Tina-quant D-dimer Gen. 2, and INNOVANCE D-dimer 

    Tønne, Brita; Pedersen, Marit Holmefjord; Frønæs, Synne Grønvold; Jørgensen, Camilla Tøvik; Amundsen, Erik Koldberg; Mæhlum, Julie Berge; Berg, Thea; Mathisen, Åse-Berit; Ghanima, Waleed; Garabet, Lamya Samir Noori (Journal article; Peer reviewed, 2023)
    Introduction: D-dimer is a crucial test to exclude deep vein thrombosis (DVT). We aimed to evaluate the per- formance of three D-dimer assays: STA-Liatest D-Di Plus (Diagnostica Stago), Tina-quant D-Dimer Gen. 2 (Roche ...
  • Intraorale formuleringer - moderne produkter og potensialet i fremtidige nanobaserte formuleringer 

    Nguyen, Sanko; Hiorth, Marianne (Peer reviewed; Journal article, 2023)
    Hensikt: Lokalbehandling av munnhulen er svært utfordrende samtidig som helseproblemer i munnhulen er et økende problem i befolkningen. Hensikten med denne oversiktsartikkelen er å gi et innblikk i moderne administrasjonssystemer ...
  • Effect of CYP2D6 genotype on duloxetine serum concentration 

    Hole, Kristine; Gangsø, Sofie; Jensstuen, Åse Tonette; Ormøy, Hanne Holte; Paulsen, Maren; Molden, Espen; Haslemo, Tore (Peer reviewed; Journal article, 2023)
    Duloxetine is metabolized by cytochrome P450 (CYP)1A2 and CYP2D6. The aim of this study was to investigate the effect of the CYP2D6 genotype on duloxetine serum concentration adjusting for age and sex. Patients were included ...
  • Prediction of Age Older than 18 Years in Sub-adults by MRI Segmentation of 1st and 2nd Molars 

    Bjørk, Mai Britt; Kvaal, Sigrid Ingeborg; Bleka, Øyvind; Sakinis, Tomas; Tuvnes, Frode Alexander; Haugland, Mari-Ann; Eggesbø, Heidi Beate; Lauritzen, Peter Mæhre (Journal article; Peer reviewed, 2023)
    Purpose To investigate prediction of age older than 18 years in sub-adults using tooth tissue volumes from MRI segmenta- tion of the entire 1st and 2nd molars, and to establish a model for combining information from two ...
  • Optimized SPECT Imaging of 224Ra α-Particle Therapy by 212Pb Photon Emissions 

    Mikalsen, Lars Tore Gyland; Kvassheim, Monika; Stokke, Caroline (Peer reviewed; Journal article, 2023)
    In preparation for an a-particle therapy trial using 1–7 MBq of 224Ra, the feasibility of tomographic SPECT/CT imaging was of interest. The nuclide decays in 6 steps to stable 208Pb, with 212Pb as the principle photon-emitting ...
  • Optimization of Q.Clear reconstruction for dynamic 18F PET imaging 

    Lysvik, Elisabeth Kirkeby; Mikalsen, Lars Tore Gyland; Rootwelt-Revheim, Mona Elisabeth; Emblem, Kyrre Eeg; Hjørnevik, Trine (Journal article; Peer reviewed, 2023)
    Background: Q.Clear, a Bayesian penalized likelihood reconstruction algorithm, has shown high potential in improving quantitation accuracy in PET systems. The Q.Clear algorithm controls noise during the iterative reconstruction ...
  • Age prediction in sub-adults based on MRI segmentation of 3rd molar tissue volumes 

    Bjørk, Mai Britt; Kvaal, Sigrid Ingeborg; Bleka, Øyvind; Sakinis, Tomas; Tuvnes, Frode Alexander; Haugland, Mari-Ann; Lauritzen, Peter Mæhre; Eggesbø, Heidi Beate (Peer reviewed; Journal article, 2023)
    Purpose Our aim was to investigate tissue volumes measured by MRI segmentation of the entire 3rd molar for prediction of a sub-adult being older than 18 years. Material and method We used a 1.5-T MR scanner with a ...
  • The impact of body compositions on contrast medium enhancement in chest CT: a randomised controlled trial 

    Henning, Mette Karen; Aaløkken, Trond Mogens; Martinsen, Anne Catrine Trægde; Johansen, Safora (Peer reviewed; Journal article, 2023)
    Objective: To compare a fixed-volume contrast medium (CM) protocol with a combined total body weight (TBW) and body composition-tailored protocol in chest CT. Methods and materials: Patients referred for routine contrast ...
  • MRI segmentation of tooth tissue in age prediction of sub-adults — a new method for combining data from the 1st, 2nd, and 3rd molars 

    Bjørk, Mai Britt; Bleka, Øyvind; Kvaal, Sigrid Ingeborg; Sakinis, Tomas; Tuvnes, Frode Alexander; Eggesbø, Heidi Beate; Lauritzen, Peter Mæhre (Peer reviewed; Journal article, 2023)
    Purpose WeaimedtoestablishamodelcombiningMRIvolumemeasurementsfromthe1st,2ndand3rdmolarsforageprediction in sub-adults and compare the age prediction performance of different combinations of all three molars, internally ...
  • Halved contrast medium dose in lower limb dual-energy computed tomography angiography—a randomized controlled trial 

    Kristiansen, Cathrine Helgestad; Thomas, Owen Matthew Truscott; Tran, Thien Trung; Roy, Sumit K; Hykkerud, Dan L; Sanderud, Audun; Geitung, Jonn Terje; Lauritzen, Peter Mæhre (Peer reviewed; Journal article, 2023)
    Objectives To compare vascular attenuation (VA) of an experimental half iodine-load dual-layer spectral detector CT (SDCT) lower limb computed tomography angiography (CTA) with control (standard iodine-load conventional ...
  • Contribution of Small Extracellular Vesicles from Schwann Cells and Satellite Glial Cells to Pain Processing 

    Gazerani, Parisa (Peer reviewed; Journal article, 2024)
    Extracellular vesicles (EVs), including exosomes and microvesicles, are membrane-bound particles released by cells into extracellular space. These vesicles carry various molecules, such as proteins and lipids, and can ...

View more