Browsing HV - Institutt for naturvitenskapelige helsefag by Title
Now showing items 166-185 of 407
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Hyperactivation of NF-κB via the MEK signaling is indispensable for the inhibitory effect of cAMP on DNA damage-induced cell death.
(Molecular Cancer;10 (45), Journal article; Peer reviewed, 2011-04-21)With cAMP signaling having a profound inhibitory effect on DNA damage-induced apoptosis in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells, understanding how this signaling pathway affects the survival capacity ... -
'I try not to bother the residents too much' - the use of capillary blood glucose measurements in nursing homes
(Journal article; Peer reviewed, 2016)Background Capillary blood glucose measurements are regularly used for nursing home residents with diabetes. The usefulness of these measurements relies on clear indications for use, correct measurement techniques, ... -
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor
(Nature Genetics;Volume 49, Issue 7, Journal article; Peer reviewed, 2017-06-12)Genome-wide association studies (GWAS) have transformed our understanding of testicular germ cell tumour (TGCT) susceptibility but much of the heritability remains unexplained. Here we report a new GWAS, a meta-analysis ... -
Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients—a genome-wide association study adjusting for smoking habits
(Translational Psychiatry; 10, Article number: 198 (2020), Journal article; Peer reviewed, 2020-06-19)Clozapine (CLZ) is the superior antipsychotic drug for treatment of schizophrenia, but exhibits an extensive interpatient pharmacokinetic variability. Here, we conducted a genome-wide association study (GWAS) of CLZ serum ... -
Identification of differentially expressed Atlantic salmon miRNAs responding to salmonid alphavirus (SAV) infection
(Journal article; Peer reviewed, 2017)Background MicroRNAs (miRNAs) control multiple biological processes including the innate immune responses by negative post-transcriptional regulation of gene expression. As there were no studies on the role(s) of miRNAs ... -
Imaging in Lyme neuroborreliosis
(Insight into Imaging;October 2018, Volume 9, Issue 5, Journal article; Peer reviewed, 2018-09-04)Lyme neuroborreliosis (LNB) is a tick-borne spirochetal infection with a broad spectrum of imaging pathology. For individuals who live in or have travelled to areas where ticks reside, LNB should be considered among ... -
Imaging predictors of response to cardiac resynchronization therapy: left ventricular work asymmetry by echocardiography and septal viability by cardiac magnetic resonance
(European Heart Journal;Volume 41, Issue 39, Journal article; Peer reviewed, 2020-09-11)Aims: Left ventricular (LV) failure in left bundle branch block is caused by loss of septal function and compensatory hyperfunction of the LV lateral wall (LW) which stimulates adverse remodelling. This study investigates ... -
Imaging the tumour microenvironment in rectal cancer: Decline in tumour blood flow during radiotherapy predicts good outcome
(Peer reviewed; Journal article, 2023)Background and purpose Measuring rectal tumour response to radiation is pivotal to restaging patients and for possibly stratification to a watch-and-wait strategy. Recognizing the importance of the tumour microenvironment, ... -
The impact of body compositions on contrast medium enhancement in chest CT: a randomised controlled trial
(Peer reviewed; Journal article, 2023)Objective: To compare a fixed-volume contrast medium (CM) protocol with a combined total body weight (TBW) and body composition-tailored protocol in chest CT. Methods and materials: Patients referred for routine contrast ... -
Impact of growing up with somatic long-term health challenges on school completion, NEET status and disability pension: a population-based longitudinal study
(BMC Public Health;21, Article number: 514 (2021), Peer reviewed; Journal article, 2021-03-16)Background: Young adulthood is an important transitional life phase that can determine a person’s educational and employment trajectories. The aim of this study was to examine the impact of somatic long-term health challenges ... -
Impact of hyperfractionated re-irradiation on quality of life in patients with recurrent or second primary head and neck cancer, a prospective single institutional study
(Peer reviewed; Journal article, 2023)Purpose Describe the clinical outcome of hyperfractionated re-irradiation (HFRT) in patients with recurrent or second primary (SP) head and neck cancer (HNC). Methods This prospective observational study included HNC ... -
Impact of initial emotional states and self-efficacy changes on nursing students’ practical skills performance in simulation-based education
(Nursing Reports;Volume 11, Issue 2, Peer reviewed; Journal article, 2021-04-21)Training through simulation has shown to increase relevant and specific skills sets across a wide range of areas in nursing and related professions. Increasing skills has a reciprocal relation to the development of ... -
Impact of iodine concentration and scan parameters on image quality, contrast enhancement and radiation dose in thoracic CT
(European Radiology Experimental;4, Article number: 57 (2020), Journal article; Peer reviewed, 2020-09-11)Background: We investigated the impact of varying contrast medium (CM) densities and x-ray tube potentials on contrast enhancement (CE), image quality and radiation dose in thoracic computed tomography (CT) using two ... -
The impact of operator training on the accuracy of DXA lumbar spine analysis
(OPTIMAX 2018 - a focus on education in radiology;, Chapter; Peer reviewed, 2019)Introduction: This study involving Dual-energy X-ray Absorptiometry (DXA) spine images investigated the effectiveness of an additional training session compared to basic instruction provided by the scanner manufacturer ... -
The impact of pitch values on image quality and radiation dose in an abdominal adult phantom using CT
(Chapter; Peer reviewed, 2017)Purpose: To identify the impact of different pitch values on image quality and effective radiation dose for axial and coronal plane in abdominal adult CT. Methods and materials: Three scans were conducted on an abdominal ... -
Impact of the anode heel effect on image quality and effective dose for AP pelvis: a pilot study
(Chapter; Peer reviewed, 2017)Purpose: Using phantoms, this pilot study aims to outline a method and generate initial data to determine whether the anode heel effect has an impact on image quality and the effective dose. Methods and Materials: A ... -
Implications of stx loss for clinical diagnostics of Shiga toxin-producing Escherichia coli
(European Journal of Clinical Microbiology and Infectious Diseases;Volume 37, Issue 12, Journal article; Journal article; Peer reviewed, 2018-09-28)The dynamics related to the loss of stx genes from Shiga toxin-producing Escherichia coli remain unclear. Current diagnostic procedures have shortcomings in the detection and identification of STEC. This is partly owing ... -
In-office thermal systems for the treatment of dry eye disease
(Survey of ophthalmology;Volume 67, Issue 5, September–October 2022, Peer reviewed; Journal article, 2022-08-12)Dry eye disease affects millions of people worldwide, causing pain, vision disturbance, and reduced productivity. Meibomian gland dysfunction, a major cause of dry eye, is characterized by chronic glandular inflammation, ... -
Increased COVID-19 testing rates following combined door-to-door and mobile testing facility campaigns in Oslo, Norway, a difference-in-difference analysis
(International Journal of Environmental Research and PuInternational Journal of Environmental Research and Public Health (IJERPH);Volume 18 / Issue 21, Peer reviewed; Journal article, 2021-10-21)High testing rates limit COVID-19 transmission. Attempting to increase testing rates, Stovner District in Oslo, Norway, combined door-to-door campaigns with easy access testing facilities. We studied the intervention’s ... -
Increased glycolysis and higher lactate production in hyperglycemic myotubes
(Cells;Volume 8, Issue 9, Journal article; Peer reviewed, 2019-09-18)Previous studies have shown that chronic hyperglycemia impairs glucose and fatty acid oxidation in cultured human myotubes. To further study the hyperglycemia-induced suppression of oxidation, lactate oxidation, mitochondrial ...