Browsing HV - Master i Biomedisin by Title
Now showing items 34-53 of 92
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Epigenetic and genetic influence on radiation responce.
(Master thesis, 2011)Clinical experience has demonstrated that some tumors are more resistant towards ionizing radiation than others. There is strong evidence that both genetic and epigenetic characteristics of the tumor and surrounding tissue ... -
Establishing in house workflow for detection and genotyping waterborne Escherichia coli by next generation whole genome sequencing using Ion Torrent PGM platform
(MABIOD;2017, Master thesis, 2017)Brusdalsvannet is a 7.52 km² drinking water reservoir located in Aalesund commune, surrounded by forest with high canopy cover on one side, dense habitation and the main highway into Aalesund on the other side. Consequently, ... -
Establishment and characterization of cell lines to study the proxymitome of the Centrosome and Spindle Pole-associated protein 1
(Master thesis, 2021)The predominantly expressed isoform of CSPP1, CSPP-L, is a centrosomal and Centriolar satellite protein with functions in microtubule organization in cell division and cilia formation. CSPP-L dose and microtubule organizing ... -
Establishment of a new quantitative method for in situ detection of DNA breaks in human spermatozoa
(Master thesis, 2021)Background: There is increasing evidence that infertile men have higher levels of DNA fragmentation compared to fertile men. It was also shown that spermatozoa with highly fragmented DNA are less motile. Several tests are ... -
Establishment of a new quantitative method for in situ detection of DNA breaks in human spermatozoa
(Master thesis, 2021-05)Background: There is increasing evidence that infertile men have higher levels of DNA fragmentation compared to fertile men. It was also shown that spermatozoa with highly fragmented DNA are less motile. Several tests are ... -
Establishment of PCR based methods for detection of ctDNA in blood
(Master thesis, 2013)Cell-free DNA appears in the circulation when cells undergo apoptosis and necrosis. This is a natural process and small amounts of cell-free DNA can be found in the blood of healthy individuals. When tumors are present, a ... -
Establishment of the Ba/F3 method to test the oncogenic potential of cancer gene mutations
(Master thesis, 2013) -
Establishment of vitamin D receptor chromatin immunoprecipitation in CD8+ T cells to identify new vitamin D receptor binding sites.
(MABIO;2019, Master thesis, 2019)Multiple sclerosis (MS) is an autoimmune neurodegenerative disorder of the central nervous system (CNS). Although, the cause of MS is still unknown, some genetical and environmental risk factor are known to be involved ... -
Etterlevelse av retningslinjene for venøs blodprøvetaking blant ulike grupper helsepersonell
(MABIO;2017, Master thesis, 2017)Bakgrunn Korrekt utførelse av venøs blodprøvetaking er viktig for pasient- sikkerheten og manglende etterlevelse av retningslinjene kan påvirke både diagnostikk og behandling. I denne studien var det et ønske om å undersøke ... -
Exploring changes in long non-coding RNAs during neonatal hypoxia-ischemia using a piglet model
(Master thesis, 2021)Background: Despite major advances in research and clinical care during the last decade, hypoxic-ischemic encephalopathy (HIE) remains one of the leading causes worldwide of death and disability in children under five years ... -
EXPLORING CHANGES IN LONG NON-CODING RNAS DURING NEONATAL HYPOXIA-ISCHEMIA USING A PIGLET MODEL
(Master thesis, 2021-05)Background: Despite major advances in research and clinical care during the last decade, hypoxic-ischemic encephalopathy (HIE) remains one of the leading causes worldwide of death and disability in children under five years ... -
Fluorescence in situ hybridisation BRAF-mutation analysis on pre-stained smears from thyroid fine-needle aspiration cytology
(MABIO;2019, Master thesis, 2019)Background: PTC is a differentiated thyroid carcinoma and the most common (70-80%) among all thyroid cancers. BRAFV600E-mutation is the most prevalent in PTC and a highly sensitive marker. Ultrasoundguided fine-needle ... -
Fotokjemisk internalisering (PCI) som metode for aktivering av terapeutiske makromolekyler : evaluering av betydningen av autofagi for behandlingseffekt
(Master thesis, 2010)Kreft forventes å ramme hver tredje nordmann. Dagens kreftbehandlinger inkluderer hovedsakelig kirurgi, kjemoterapi og strålebehandling. Fotodynamisk terapi (PDT) er en relativ ny form for strålebehandling som utnytter ... -
Fotokjemisk internalisering av immuntoksiner rettet mot kreftstamcellemarkørene CD44 og CD90 i karsinomer og sarkomer
(Master thesis, 2013)Overflateproteinene CD44 og CD90 er identifisert som potensielle markører for kreftstamceller i flere typer kreft, og antas å være mulige terapeutiske mål for økt spesifikk behandling av kreftceller med stamcellelignende ... -
Gas chromatographic analysis of phospholipid fatty acids in human serum - Serum phospholipid fatty acid composition in relation to overweight, semen quality and weight loss
(Master thesis, 2013)Introduction: The increasing prevalence of overweight and obesity has become one of the major health concerns in modern times. Male obesity has been associated with decreased male reproduction function and fertility in ... -
GCN2 as a therapeutic target for prostate cancer
(Master thesis, 2021-08)Background: Prostate cancer (PC) is the second most common cancer in men worldwide. Primary PC is treated by surgery, radiotherapy or high dose-rate brachytherapy and androgen deprivation therapy (ADT) – and this is usually ... -
General control nonderepressible two (GCN2) as a therapeutic target for prostate cancer
(Master thesis, 2021)Prostate cancer (PC) is the second most common cancer in men worldwide. Primary PC is treated by surgery, radiotherapy or high dose-rate brachytherapy and androgen deprivation therapy (ADT) – and this is usually very ... -
Head CT after minimal, mild and moderate traumatic brain injury: Audit of clinical practice
(MABIO;2020, Master thesis, 2020)Introduction: Traumatic brain injury (TBI), commonly classified as minimal, mild, moderate and severe, is one of the most common presentations in an Emergency Department (ED). Majority of TBIs are classified as minimal and ... -
High fat diet exposure during different life stages in mice and consequences for metabolic programming in the liver
(MABIOD;2018, Master thesis, 2018)Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the world, and is the hepatic manifestation of the metabolic syndrome. Obesity is closely associated with NAFLD. The concept of fetal ... -
HPV chromosomal integration as a biomarker for cancer progression
(Master thesis, 2021)Background: Human papillomavirus (HPV) is associated with 4,5% of all human cancers worldwide including cervical cancer. Cytological and/or HPV primary screening is used to uncover cancer precursors. Still, better clinical ...