Akershus Universitetssykehus HF
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Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study
(Atherosclerosis;289, Journal article; Peer reviewed, 2019-10)Abstract Background and aims Several risk prediction models for coronary heart disease (CHD) are available today, however, they only explain a modest proportion of the incidence. Circulating microRNAs (miRs) have ... -
Plasma marine n-3 polyunsaturated fatty acids and cardiovascular risk factors: data from the ACE 1950 study
(European journal of nutrition;, Journal article; Peer reviewed, 2019-05-23)Abstract Purpose A high intake of marine n-3 polyunsaturated fatty acids (PUFAs) might improve cardiovascular (CV) health. We conducted a cross-sectional study to investigate associations between plasma phospholipid ... -
Surgical site infection after hip fracture – mortality and risk factors: an observational cohort study of 1,709 patients
(Acta Orthopaedica;1-6, Journal article; Peer reviewed, 2020-01-24)Abstract Background and purpose — Surgical site infection (SSI) is a devastating complication of hip fracture surgery. We studied the contribution of early deep SSI to mortality after hip fracture surgery and the risk ... -
Cognitive behavior therapy in early psychosis with a focus on depression and low self-esteem: A randomized controlled trial
(Comprehensive Psychiatry;97, Journal article; Peer reviewed, 2020-02)Background Patients in early phases of psychosis often struggle with depressive symptoms and low self-esteem. The main aims of the present study were to examine whether cognitive behavior therapy (CBT) compared to ... -
Design of the CAPABLE Prototype: Preliminary Results of Citizen Expectations
(Linköping Electronic Conference Proceedings;161, Conference object, 2019-11)Having access to and opportunity to an overview of all personal health-related information is important to citizen health empowerment. Today, citizens can access subsets of their health information through dedicated, ... -
Fast track hip fracture care and mortality – an observational study of 2230 patients
(BMC Musculoskeletal Disorders;20 (1), Journal article; Peer reviewed, 2019-05-24)Background Hip fracture patients are frail and have a high mortality. We investigated whether the introduction of fast track care reduced the 30-day mortality after hip fractures. Methods Fast track hip fracture ... -
Assessing severity in pediatric pneumonia. Predictors of the need for major medical interventions
(Pediatric emergency care;, Journal article; Peer reviewed, 2017)Objective: The aim of this study was to determine potential predictors of the need for major medical interventions in the context of assessing severity in pediatric pneumonia. Methods: This was a prospective, cohort ... -
NAD+ in aging: molecular mechanisms and translational implications
(Trends in Molecular Medicine;23/10, Journal article; Peer reviewed, 2017-10)AB The coenzyme NAD+ is critical in cellular bioenergetics and adaptive stress responses. Its depletion has emerged as a fundamental feature of aging that may predispose to a wide range of chronic diseases. Maintenance of ... -
Clinical features and inflammatory markers in pediatric pneumonia: a prospective study
(European journal of pediatrics;176(5), Journal article; Peer reviewed, 2017-03-09)Abstract In this prospective, observational study on previously healthy children <18 years, we aimed to study the diagnostic ability of clinical features and inflammatory markers to (i) predict pathologic chest radiography ... -
Change in psychotropic drug use in Norwegian nursing homes between 2004 and 2011
(International psychogeriatrics;30(3), Peer reviewed; Journal article, 2017-10-09)Background: We aimed to assess whether there were any changes in the use of psychotropic drugs in Norwegian nursing homes between 2004 and 2011. Also, we investigated whether the predictors of use of specific psychotropic ... -
Flexor hallucis longus tendon transfer for chronic Achilles tendon rupture. A retrospective study
(Foot and Ankle Surgery;, Journal article; Peer reviewed, 2018-07-18)Background The transfer of Flexor Hallucis Longus Tendon (FHL) is an established method for the treatment of chronic Achilles tendon ruptures. An extensive examination of power, strength, endurance and complications related ... -
Improved Survival after Implementation of Multidisciplinary Team Meetings, Perioperative Chemotherapy, Extended Lymphnode Dissection and Laparoscopic Surgery in the Treatment of Advances Gastric Cancer
(Journal of Cancer Therapy;9(2), Journal article; Peer reviewed, 2018-02)Aims: The treatment of gastric cancer has changed in the western countries during the last decade. This includes multidisciplinary team (MDT) meetings, perioperative chemotherapy, extended lymph node dissection, and ... -
Introducing anatomically correct CT-guided laparoscopic right colectomy with D3 anterior posterior extended mesenterectomy: Initial experience and technical pitfalls
(Journal of Laparoendoscopic & Advanced Surgical Techniques;28(10), Journal article; Peer reviewed, 2018-10-10)Background: Laparoscopic D3 anterior posterior extended mesenterectomy (D3APEM) in right colectomy has received increased attention. The aim of this study is to prove feasibility, systemize technical accomplishment, and ... -
A Norwegian 15D value algorithm: proposing a new procedure to estimate 15D value algorithms
(Quality of Life Research;28(5), Journal article; Peer reviewed, 2018-11-30)Purpose So far there is no Norwegian value algorithm to inform healthcare decision making. The 15D health state values estimated with the original 15D valuation procedure tend to be higher than the values of other generic ... -
Serum cytokine levels in breast cancer patients during neoadjuvant treatment with bevacizumab
(Oncoimmunology;7(11), Journal article; Peer reviewed, 2018-01-08)A high concentration of circulating vascular endothelial growth factor (VEGF) in cancer patients is associated with an aggressive tumor phenotype. Here, serum levels of 27 cytokines and blood cell counts were assessed in ... -
Noninvasive profiling of serum cytokines in breast cancer patients and clinicopathological characteristics
(Oncoimmunology;8(2), Journal article; Peer reviewed, 2018-06-05)Cancers elicit an immune response by modifying the microenvironment. The immune system plays a pivotal role in cancer recognition and eradication. While the potential clinical value of infiltrating lymphocytes at the tumor ... -
The copeptin response after physical activity is not associated with cardiac biomarkers or asymptomatic coronary artery disease: The North Sea Race Endurance Exercise Study (NEEDED) 2013
(Clinical biochemistry;52, Journal article; Peer reviewed, 2017-10-26)Background:Copeptin concentrations increase both during acute coronary syndrome and following physicalexercise. The relationship between copeptin increase following physical exercise and coronary artery disease(CAD) is ... -
No associations established between single nucleotide polymorphisms in human Toll-like receptor 2 and Toll-interacting protein and Staphylococcus aureus bloodstream infections
(Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS);125(10), Journal article; Peer reviewed, 2017-07-24)Staphylococcus aureus bloodstream infections (SABSI) are associated with high morbidity and mortality. The Toll‐like receptor 2 (TLR2) and Toll‐interacting protein (TOLLIP) are important in recognition and regulation of ... -
Left ventricular biomechanics in professional football players
(Scandinavian journal of medicine & science in sports;28(1), Journal article; Peer reviewed, 2017-04-04)Chronic exercise induces adaptive changes of left ventricular (LV) ejection and filling capacities which may be detected by novel speckle‐tracking echocardiography (STE) and tissue Doppler imaging (TDI)‐based techniques. ... -
Epidemiology of distal radius fracture in Akershus, Norway, in 2010-2011
(Journal of orthopaedic surgery and research;13(1), Journal article; Peer reviewed, 2018-08-13)Background Several studies published over the last decade indicate an increased incidence of distal radius fractures (DRF). With Norway having one of the highest reported incidence of DRFs, we conducted a study to assess ...