AHUS - Diagnostikk og teknologi
Recent Submissions
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Design of the CAPABLE Prototype: Preliminary Results of Citizen Expectations
(Linköping Electronic Conference Proceedings;161, Conference object, 2019-11)Having access to and opportunity to an overview of all personal health-related information is important to citizen health empowerment. Today, citizens can access subsets of their health information through dedicated, ... -
Serum cytokine levels in breast cancer patients during neoadjuvant treatment with bevacizumab
(Oncoimmunology;7(11), Journal article; Peer reviewed, 2018-01-08)A high concentration of circulating vascular endothelial growth factor (VEGF) in cancer patients is associated with an aggressive tumor phenotype. Here, serum levels of 27 cytokines and blood cell counts were assessed in ... -
Noninvasive profiling of serum cytokines in breast cancer patients and clinicopathological characteristics
(Oncoimmunology;8(2), Journal article; Peer reviewed, 2018-06-05)Cancers elicit an immune response by modifying the microenvironment. The immune system plays a pivotal role in cancer recognition and eradication. While the potential clinical value of infiltrating lymphocytes at the tumor ... -
The copeptin response after physical activity is not associated with cardiac biomarkers or asymptomatic coronary artery disease: The North Sea Race Endurance Exercise Study (NEEDED) 2013
(Clinical biochemistry;52, Journal article; Peer reviewed, 2017-10-26)Background:Copeptin concentrations increase both during acute coronary syndrome and following physicalexercise. The relationship between copeptin increase following physical exercise and coronary artery disease(CAD) is ... -
No associations established between single nucleotide polymorphisms in human Toll-like receptor 2 and Toll-interacting protein and Staphylococcus aureus bloodstream infections
(Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS);125(10), Journal article; Peer reviewed, 2017-07-24)Staphylococcus aureus bloodstream infections (SABSI) are associated with high morbidity and mortality. The Toll‐like receptor 2 (TLR2) and Toll‐interacting protein (TOLLIP) are important in recognition and regulation of ... -
Initial Phase NT-proBNP, but Not Copeptin and High-Sensitivity Cardiac Troponin-T Yielded Diagnostic and Prognostic Information in Addition to Clinical Assessment of Out-of-Hospital Cardiac Arrest Patients With Documented Ventricular Fibrillation
(Frontiers in cardiovascular medicine;5, Journal article; Peer reviewed, 2018-06-07)Aim: Sudden cardiac arrest (SCA) secondary to ventricular fibrillation (VF) may be due to different cardiac conditions. We investigated whether copeptin, hs-cTnT and NT-proBNP in addition to clinical assessment may help ... -
Somatic EP300-G211S mutations are associated with overall somatic mutational patterns and breast cancer specific survival in triple-negative breast cancer
(Breast cancer research and treatment;172(2), Journal article; Peer reviewed, 2018-08-21)Purpose We have compared the mutational profiles of human breast cancer tumor samples belonging to all major subgroups with special emphasis on triple-negative breast cancer (TNBC). Our major goal was to identify specific ... -
The Valgent4 protocol: Robust analytical and clinical validation of 11 HPV assays with genotyping on cervical samples collected in SurePath medium
(Journal of Clinical Virology;108, Journal article; Peer reviewed, 2018-09-14)Background The VALidation of HPV GENoyping Tests (VALGENT) is an international initiative designed to validate HPV assays with genotyping capability. The VALGENT4 protocol differs from previous VALGENT installments as the ... -
Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations
(Genome medicine;10(1), Journal article; Peer reviewed, 2018-11-29)Background Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) and inhibits its ... -
Interval breast cancer rates and histopathologic tumor characteristics after false-positive findings at mammography in a populationbased screening program
(Radiology;287(1), Journal article; Peer reviewed, 2017-12-14)Purpose To compare rates and tumor characteristics of interval breast cancers (IBCs) detected after a negative versus false-positive screening among women participating in the Norwegian Breast Cancer Screening ... -
Betydningen av ulike kanaler i verving av blodgivere
(Bioingeniøren;2, Journal article; Peer reviewed, 2018-02-21)Formål: Studiens mål var å fremskaffe kunnskap om ulike måter blodgivere blir rekruttert til blodbanken. Det ble undersøkt om rekrutteringsmåtene blir påvirket av demografiske variabler og om andelene i rekrutteringsmåter ... -
Bioingeniøren som diagnostisk samarbeidspartner i helsevesenet
(Bioingeniøren;2018(4), Journal article; Peer reviewed, 2018-04-27)Bakgrunn. Målet med denne studien var å undersøke om en bioingeniør kan inngå som en diagnostisk samarbeidspartner (DSP) og derved oppleves som en naturlig del av et tverrprofesjonelt team i helsevesenet. Metode. Det ... -
Helseatferd blant blodgivere
(Journal article; Peer reviewed, 2018-10-02)Formål: Formålet med denne studien var å kartlegge helseatferd (tobakks- og alkoholbruk og fysisk aktivitet) i et utvalg av blodgivere, og undersøke i hvilken grad resultatene fra studien gjenspeiler helseatferd i den ... -
Tumor-associated macrophages are strongly related to vascular invasion, non-luminal subtypes, and interval breast cancer
(Human Pathology;69, Journal article; Peer reviewed, 2017-11)Tumor-associated macrophages (TAM) resemble M2 macrophages, promote tumor invasion and show strong expression of CD163 in breast cancer. We here investigated the association between CD163-positive macrophages and vascular ... -
Norwegian patients and retail chicken meat share cephalosporin-resistant Escherichia coli and IncK/blaCMY-2 resistance plasmids
(Clinical microbiology and infection;23(6), Journal article; Peer reviewed, 2017-06)Objectives In 2012 and 2014 the Norwegian monitoring programme for antimicrobial resistance in the veterinary and food production sectors (NORM-VET) showed that 124 of a total of 406 samples (31%) of Norwegian retail ... -
Ankylosing Spondylitis and Axial Spondyloarthritis in Patients With Long-term Inflammatory Bowel Disease: Results From 20 Years of Follow-up in the IBSEN Study
(Journal of Crohn's and Colitis;12(1), Journal article; Peer reviewed, 2017-09-13)Background Patients with inflammatory bowel disease [IBD] often suffer from rheumatic manifestations, including inflammatory back disorders. The prevalence of these disorders late in the course of IBD is poorly investigated. ... -
Extra-nodal extension is a significant prognostic factor in lymph node positive breast cancer
(PloS one;12(2), Journal article; Peer reviewed, 2017-02-15)Presence of lymph node (LN) metastasis is a strong prognostic factor in breast cancer, whereas the importance of extra-nodal extension and other nodal tumor features have not yet been fully recognized. Here, we examined ... -
Peripheral arthritis in patients with long-term inflammatory bowel disease. Results from 20 years of follow-up in the IBSEN study
(Scandinavian Journal of Gastroenterology;53(10-11), Journal article; Peer reviewed, 2018-10-24)Objectives: Peripheral arthritis and related musculoskeletal manifestations, often classified as peripheral spondyloarthritis, are frequently seen in patients with inflammatory bowel disease (IBD). Few long-term studies ... -
A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America
(BMC cancer;17(1), Journal article; Peer reviewed, 2017-09-05)Background Genetic counselling and testing for Lynch syndrome (LS) have recently been introduced in several Latin America countries. We aimed to characterize the clinical, molecular and mismatch repair (MMR) variants ... -
Genotypic characterization of gentamicin and cephalosporin 1 resistant Escherichia coli 2 isolates from blood cultures in a Norwegian university hospital 2011-2015
(Antimicrobial Resistance & Infection Control;121(6), Journal article; Peer reviewed, 2017-11-29)Background: Cephalosporin resistance in clinical E. coli isolates is increasing internationally. The increase has been caused by virulent and often multidrug-resistant clones, especially the extended spectrum beta-lactamase ...