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Immune cell subpopulations and serum neurofilament light chain are associated with increased risk of disease worsening in multiple sclerosis

dc.contributor.authorBrune-Ingebretsen, Synne
dc.contributor.authorHøgestøl, Einar August
dc.contributor.authorde Rosbo, Nicole Kerlero
dc.contributor.authorBerg-Hansen, Pål
dc.contributor.authorBrunborg, Cathrine
dc.contributor.authorBlennow, Kaj
dc.contributor.authorZetterberg, Henrik
dc.contributor.authorPaul, Friedemann
dc.contributor.authorUccelli, Antonio
dc.contributor.authorVilloslada, Pablo
dc.contributor.authorHarbo, Hanne-Cathrin Flinstad
dc.contributor.authorBerge, Tone
dc.date.accessioned2023-11-22T08:00:23Z
dc.date.available2023-11-22T08:00:23Z
dc.date.created2023-10-06T12:21:28Z
dc.date.issued2023
dc.identifier.citationJournal of Neuroimmunology. 2023, 382 .en_US
dc.identifier.issn0165-5728
dc.identifier.urihttps://hdl.handle.net/11250/3103986
dc.description.abstractChanges is lymphocyte subpopulations in peripheral blood have been proposed as biomarkers for evaluation of disease activity in multiple sclerosis (MS). Serum neurofilament light chain (sNfL) is a biomarker reflecting neuro-axonal injury in MS that could be used to monitor disease activity, response to drugs and to prognosticate disease course. Here we show a moderate correlation between sNfL and lymphocyte cell subpopulations, and our data furthermore suggest that sNfL and specific immune cell subpopulations together could predict future disease worsening in MS.en_US
dc.language.isoengen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleImmune cell subpopulations and serum neurofilament light chain are associated with increased risk of disease worsening in multiple sclerosisen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.doi10.1016/j.jneuroim.2023.578175
dc.identifier.cristin2182420
dc.source.journalJournal of Neuroimmunologyen_US
dc.source.volume382en_US
dc.source.pagenumber11en_US


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal