Immune cell subpopulations and serum neurofilament light chain are associated with increased risk of disease worsening in multiple sclerosis
| dc.contributor.author | Brune-Ingebretsen, Synne | |
| dc.contributor.author | Høgestøl, Einar August | |
| dc.contributor.author | de Rosbo, Nicole Kerlero | |
| dc.contributor.author | Berg-Hansen, Pål | |
| dc.contributor.author | Brunborg, Cathrine | |
| dc.contributor.author | Blennow, Kaj | |
| dc.contributor.author | Zetterberg, Henrik | |
| dc.contributor.author | Paul, Friedemann | |
| dc.contributor.author | Uccelli, Antonio | |
| dc.contributor.author | Villoslada, Pablo | |
| dc.contributor.author | Harbo, Hanne-Cathrin Flinstad | |
| dc.contributor.author | Berge, Tone | |
| dc.date.accessioned | 2023-11-22T08:00:23Z | |
| dc.date.available | 2023-11-22T08:00:23Z | |
| dc.date.created | 2023-10-06T12:21:28Z | |
| dc.date.issued | 2023 | |
| dc.identifier.citation | Journal of Neuroimmunology. 2023, 382 . | en_US |
| dc.identifier.issn | 0165-5728 | |
| dc.identifier.uri | https://hdl.handle.net/11250/3103986 | |
| dc.description.abstract | Changes is lymphocyte subpopulations in peripheral blood have been proposed as biomarkers for evaluation of disease activity in multiple sclerosis (MS). Serum neurofilament light chain (sNfL) is a biomarker reflecting neuro-axonal injury in MS that could be used to monitor disease activity, response to drugs and to prognosticate disease course. Here we show a moderate correlation between sNfL and lymphocyte cell subpopulations, and our data furthermore suggest that sNfL and specific immune cell subpopulations together could predict future disease worsening in MS. | en_US |
| dc.language.iso | eng | en_US |
| dc.rights | Navngivelse 4.0 Internasjonal | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
| dc.title | Immune cell subpopulations and serum neurofilament light chain are associated with increased risk of disease worsening in multiple sclerosis | en_US |
| dc.type | Peer reviewed | en_US |
| dc.type | Journal article | en_US |
| dc.description.version | publishedVersion | en_US |
| cristin.ispublished | true | |
| cristin.fulltext | original | |
| cristin.qualitycode | 1 | |
| dc.identifier.doi | 10.1016/j.jneuroim.2023.578175 | |
| dc.identifier.cristin | 2182420 | |
| dc.source.journal | Journal of Neuroimmunology | en_US |
| dc.source.volume | 382 | en_US |
| dc.source.pagenumber | 11 | en_US |
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