dc.contributor.author | Askeland Winje, Brita | |
dc.contributor.author | Ofitserova, Trine Skogset | |
dc.contributor.author | Brynildsrud, Ola Brønstad | |
dc.contributor.author | Greve-Isdahl, Margrethe | |
dc.contributor.author | Bragstad, Karoline | |
dc.contributor.author | Rykkvin, Rikard | |
dc.contributor.author | Hungnes, Olav | |
dc.contributor.author | Lund, Hilde Marie | |
dc.contributor.author | Nygård, Karin Maria | |
dc.contributor.author | Meijerink, Hinta | |
dc.contributor.author | Brandal, Lin Cathrine T. | |
dc.date.accessioned | 2022-03-18T08:54:26Z | |
dc.date.available | 2022-03-18T08:54:26Z | |
dc.date.created | 2022-01-03T17:55:21Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Microorganisms. 2021, 9 (12), . | en_US |
dc.identifier.issn | 2076-2607 | |
dc.identifier.uri | https://hdl.handle.net/11250/2986063 | |
dc.description.abstract | The role of children in the spread of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in schools has been a topic of controversy. In this study among school contacts of
SARS-CoV-2 positive children in 43 contact-investigations, we investigated SARS-CoV-2 transmission
in Norway, August 2020–May 2021. All participants were tested twice within seven to ten days,
using SARS-CoV-2 PCR on home-sampled saliva. Positive samples were whole genome sequenced.
Among the 559 child contacts, eight tested positive (1.4%, 95% CI 0.62–2.80), with no significant
difference between primary (1.0%, 95% CI 0.27–2.53) and secondary schools (2.6%, 95% CI 0.70–6.39),
p = 0.229, nor by viral strain, non-Alpha (1.4%, 95% CI 0.50–2.94) and Alpha variant (B.1.1.7) (1.7%,
95% CI 0.21–5.99), p = 0.665. One adult contact (1/100) tested positive. In 34 index cases, we detected
13 different SARS-CoV-2 Pango lineage variants, with B.1.1.7 being most frequent. In the eight
contact-investigations with SARS-CoV-2 positive contacts, four had the same sequence identity as
the index, one had no relation, and three were inconclusive. With mitigation measures in place, the
spread of SARS-CoV-2 from children in schools is limited. By excluding contact-investigations with
adult cases known at the time of enrolment, our data provide a valid estimate on the role of children
in the transmission of SARS-CoV-2 in schools. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | MDPI | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.subject | COVID-19 | en_US |
dc.subject | Children | en_US |
dc.subject | Infection | en_US |
dc.subject | Prevention | en_US |
dc.subject | Control | en_US |
dc.title | Comprehensive contact tracing, testing and sequencing show limited transmission of sars‐cov‐2 between children in schools in norway, august 2020 to may 2021 | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.3390/microorganisms9122587 | |
dc.identifier.cristin | 1973933 | |
dc.source.journal | Microorganisms | en_US |
dc.source.volume | 9 | en_US |
dc.source.issue | 12 | en_US |
dc.source.pagenumber | 14 | en_US |
dc.subject.nsi | VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Infeksjonsmedisin: 776 | en_US |