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dc.contributor.authorGodt, Johannes Jakob Clemens
dc.contributor.authorJohansen, Cathrine K.
dc.contributor.authorMartinsen, Anne Catrine Trægde
dc.contributor.authorSchulz, Anselm
dc.contributor.authorBrøgger, Helga Maria
dc.contributor.authorJensen, Kristin
dc.contributor.authorStray-Pedersen, Arne
dc.contributor.authorDormagen, Johann Baptist
dc.identifier.citationActa Radiologica Open. 2021, 10 (10), 1-11.en_US
dc.description.abstractBackground: Radiation-related cancer risk is an object of concern in CT of trauma patients, as these represent a young population. Different radiation reducing methods, including iterative reconstruction (IR), and spilt bolus techniques have been introduced in the recent years in different large scale trauma centers. Purpose: To compare image quality in human cadaver exposed to thoracoabdominal computed tomography using IR and standard filtered back-projection (FBP) at different dose levels. Material and methods: Ten cadavers were scanned at full dose and a dose reduction in CTDIvol of 5 mGy (low dose 1) and 7.5 mGy (low dose 2) on a Siemens Definition Flash 128-slice computed tomography scanner. Low dose images were reconstructed with FBP and Sinogram affirmed iterative reconstruction (SAFIRE) level 2 and 4. Quantitative image quality was analyzed by comparison of contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR). Qualitative image quality was evaluated by use of visual grading regression (VGR) by four radiologists. Results: Readers preferred SAFIRE reconstructed images over FBP at a dose reduction of 40% (low dose 1) and 56% (low dose 2), with significant difference in overall impression of image quality. CNR and SNR showed significant improvement for images reconstructed with SAFIRE 2 and 4 compared to FBP at both low dose levels. Conclusions: Iterative image reconstruction, SAFIRE 2 and 4, resulted in equal or improved image quality at a dose reduction of up to 56% compared to full dose FBP and may be used a strong radiation reduction tool in the young trauma population.en_US
dc.publisherSAGE Publicationsen_US
dc.relation.ispartofseriesActa Radiologica Open;Volume: 10, issue: 10
dc.rightsNavngivelse 4.0 Internasjonal*
dc.subjectComputed tomographyen_US
dc.subjectRadiation dosesen_US
dc.subjectImage processingen_US
dc.subjectIterative image reconstructionen_US
dc.titleIterative reconstruction improves image quality and reduces radiation dose in trauma protocols; A human cadaver studyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.rights.holder© The Author(s) 2021en_US
dc.source.journalActa Radiologica Openen_US

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