• Allele-specific expression of Parkinson’s disease susceptibility genes in human brain 

      Langmyhr, Margrete; Henriksen, Sandra Pilar; Cappelletti, Chiara; van de Berg, Wilma D. J.; Pihlstrøm, Lasse; Toft, Mathias (Scientific Reports;11, Article number: 504 (2021), Peer reviewed; Journal article, 2021-01-12)
      Genome-wide association studies have identifed genetic variation in genomic loci associated with susceptibility to Parkinson’s disease (PD), the most common neurodegenerative movement disorder worldwide. We used allelic ...
    • Assessing generalisability of deep learning-based polyp detection and segmentation methods through a computer vision challenge 

      Ali, Sharib; Ghatwary, Noha; Jha, Debesh; Isik-Polat, Ece; Polat, Gorkem; Yang, Cheng; Li, Wuyang; Galdran, Adrian; Ballester, Miguel Angel Gonzalez; Thambawita, Vajira L B; Hicks, Steven; Poudel, Sahadev; Lee, Sang-Woong; Jin, Ziyi; Gan, Tianyuan; Yu, Chenghui; Yan, JiangPeng; Yeo, Doyeob; Lee, Hyunseok Lee; Tomar, Nikhil Kumar; Haitham, Mahmood; Ahmed, Amr; Riegler, Michael Alexander; Daul, Christian; Halvorsen, Pål; Rittscher, Jens; Salem, Osama E.; Lamarque, Dominique; Cannizzaro, Renato; Realdon, Stefano; de Lange, Thomas; East, James E (Peer reviewed; Journal article, 2024)
      Polyps are well‑known cancer precursors identified by colonoscopy. However, variability in their size, appearance, and location makes the detection of polyps challenging. Moreover, colonoscopy surveillance and removal ...
    • Body composition and physical fitness in adults born small for gestational age at term: a prospective cohort study 

      Matre, Maria; Mehl, Cathrin Vano; Benum, Silje Dahl; Jussinniemi, Laura; Kajantie, Eero Olavi; Evensen, Kari Anne Indredavik (Peer reviewed; Journal article, 2023)
      There is lack of research on body composition and physical fitness in individuals born small for gestational age (SGA) at term entering mid-adulthood. We aimed to investigate these outcomes in adults born SGA at term. ...
    • The connectivity network underlying the German’s Twittersphere: a testbed for investigating information spreading phenomena 

      Schroeder, Daniel Thilo; Langguth, Johannes; Burchard, Luk; Pogorelov, Konstantin; Lind, Pedro (Peer reviewed; Journal article, 2022)
      Online social networks are ubiquitous, have billions of users, and produce large amounts of data. While platforms like Reddit are based on a forum-like organization where users gather around topics, Facebook and Twitter ...
    • Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement 

      Vigeland, Maria Dehli; Flåm, Siri Tennebø; Vigeland, Magnus Dehli; Espeland, Ansgar; Kristoffersen, Per Martin; Vetti, Nils; Wigemyr, Monica; Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Schistad, Ellina Iordanova; Haugen, Anne Julsrud; Johanessen, Anne Froholdt; Skouen, Jan Sture; Zwart, John Anker Henrik; Storheim, Kjersti; Pedersen, Linda Margareth; Lie, Benedicte Alexandra (Scientific Reports;12, Article number: 215 (2022), Peer reviewed; Journal article, 2022-01-07)
      Disability and distress caused by chronic low back pain (LBP) lacking clear pathoanatomical explanations cause huge problems both for patients and society. A subgroup of patients has Modic changes (MC), identifable by MRI ...
    • DeepFake electrocardiograms using generative adversarial networks are the beginning of the end for privacy issues in medicine 

      Thambawita, Vajira; Isaksen, Jonas L.; Hicks, Steven A.; Ghouse, Jonas; Ahlberg, Gustav; Linneberg, Allan; Grarup, Niels; Ellervik, Christina; Olesen, Morten Salling; Hansen, Torben; Graff, Claus; Holstein-Rathlou, Niels-Henrik; Strümke, Inga; Hammer, Hugo L.; Maleckar, Mary M.; Halvorsen, Pål; Riegler, Michael A.; Kanters, Jørgen K. (Scientific Reports;11, Article number: 21896 (2021), Peer reviewed; Journal article, 2021-11-09)
      Recent global developments underscore the prominent role big data have in modern medical science. But privacy issues constitute a prevalent problem for collecting and sharing data between researchers. However, synthetic ...
    • The effect of toll-like receptor ligands on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells 

      Tingstad, Ragna Husby; Norheim, Frode Amador; Haugen, Fred; Feng, Yuan Zeng; Tunsjø, Hege; Thoresen, G. Hege; Rustan, Arild Christian; Charnock, Colin; Aas, Vigdis (Scientific Reports;11, Article number: 24219 (2021), Peer reviewed; Journal article, 2021-12-20)
      Skeletal muscle plays an important role in glycaemic control and metabolic homeostasis, making it a tissue of interest with respect to type 2 diabetes mellitus. The aim of the present study was to determine if ligands of ...
    • Enhancing investigative interview training using a child avatar system: a comparative study of interactive environments 

      Zohaib Hassan, Syed; Shafiee Sabet, Saeed; Riegler, Michael Alexander; Baugerud, Gunn Astrid; Ko, Hayley Manalang; Salehi, Pegah; Røed, Ragnhild Klingenberg; Sinkerud Johnson, Miriam; Halvorsen, Pål (Peer reviewed; Journal article, 2023)
      The impact of investigative interviews by police and Child Protective Services (CPS) on abused children can be profound, making effective training vital. Quality in these interviews often falls short and current training ...
    • Explaining deep neural networks for knowledge discovery in electrocardiogram analysis 

      Hicks, Steven; Isaksen, Jonas L; Thambawita, Vajira L B; Ghouse, Jonas; Ahlberg, Gustav; Linneberg, Allan; Grarup, Niels; Strumke, Inga; Ellervik, Christina; Olesen, Morten Salling; Hansen, Torben; Graff, Claus; Holstein-Rathlou, Niels-Henrik; Halvorsen, Pål; Maleckar, Mary Margot Catherine; Riegler, Michael; Kanters, Jørgen K (Scientific Reports;11, Article number: 10949 (2021), Peer reviewed; Journal article, 2021-05-26)
      Deep learning-based tools may annotate and interpret medical data more quickly, consistently, and accurately than medical doctors. However, as medical doctors are ultimately responsible for clinical decision-making, any ...
    • Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders 

      Aas, Monica; Andreassen, Ole; Gjerstad, Johannes; Rødevand, Linn; Hjell, Gabriela; Johansen, Ingrid Torp; Lunding, Synve Hoffart; Ormerod, Monica Bettina E. Greenwood; Lagerberg, Trine Vik; Steen, Nils Eiel; Djurovic, Srdjan; Akkouh, Ibrahim Ahmed (Peer reviewed; Journal article, 2023)
      Exposure to early life trauma increases the risk of psychopathology later in life. Here we investigated if ANK3 mRNA levels influence the relationship between childhood trauma experiences and clinical characteristics in ...
    • Human activity recognition using wearable sensors, discriminant analysis, and long short-term memory-based neural structured learning 

      Uddin, Md Zia; Soylu, Ahmet (Scientific Reports;11, Article number: 16455 (2021), Peer reviewed; Journal article, 2021-08-12)
      Healthcare using body sensor data has been getting huge research attentions by a wide range of researchers because of its good practical applications such as smart health care systems. For instance, smart wearable sensor-based ...
    • Mortality and microbial diversity after allogenic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial 

      Skaarud, Kristin Aneta Joan; Hov, Johannes Espolin Roksund; Hansen, Simen Hyll; Kummen, Martin; Valeur, Jørgen; Seljeflot, Ingebjørg; Bye, Asta; Paulsen, Vemund; Lundin, Knut Erik Aslaksen; Trøseid, Marius; Tjønnfjord, Geir Erland; Iversen, Per Ole (Scientific Reports;11:11593, Peer reviewed; Journal article, 2021-06-02)
      Gut mucosal barrier injury is common following allogeneic hematopoietic stem cell transplantation (allo-HSCT) and associated with poor clinical outcomes. Diet is critical for microbial diversity, but whether nutritional ...
    • Non-linear finite element modeling of damages in bridge piers subjected to lateral monotonic loading 

      Ahmad, Aizaz; Ahmed, Awais; Iqbal, Mudassir; Muhammad Ali, Syed; Khan, Ghufranullah; M. Eldin, Syed; M. Yosri, Ahmed (Peer reviewed; Journal article, 2023)
      Bridges are among the most vulnerable structures to earthquake damage. Most bridges are seismically inadequate due to outdated bridge design codes and poor construction methods in developing countries. Although expensive, ...
    • Numerical study on existing RC circular section members under unequal impact collision 

      Yanhui, Liu; Al-Bukhaiti, Khalil; Shichun, Zhao; Abas, Hussein; Nan, Xu; Lang, Yang; Yu, Yan Xing; Han, Daguang (Scientific Reports;12, Article number: 14793 (2022), Peer reviewed; Journal article, 2022-08-30)
      Traffic accidents and derailed train-related incidents have occurred more often than ever in recent years, resulting in some economic damage and casualties. Reinforced concrete (RC) constructions often involve derailed ...
    • On evaluation metrics for medical applications of artificial intelligence 

      Hicks, Steven A.; Strumke, Inga; Thambawita, Vajira L B; Hammou, Malek; Riegler, Michael Alexander; Halvorsen, Pål (Scientific Reports;12, Article number: 5979 (2022), Peer reviewed; Journal article, 2022-04-08)
      Clinicians and software developers need to understand how proposed machine learning (ML) models could improve patient care. No single metric captures all the desirable properties of a model, which is why several metrics ...
    • A preliminary study of the use of MinION sequencing to specifcally detect Shiga toxin‑producing Escherichia coli in culture swipes containing multiple serovars of this species 

      Tunsjø, Hege; Ullmann, Ingvild Falkum; Charnock, Colin (Peer reviewed; Journal article, 2023)
      An important challenge relating to clinical diagnostics of the foodborne pathogen Shiga toxin-producing E. coli (STEC), is that PCR-detection of the shiga-toxin gene (stx) in DNA from stool samples can be accompanied by a ...