Blar i HV - Institutt for naturvitenskapelige helsefag på tittel
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Cerebral palsy in Moldova: subtypes, severity and associated impairments
(BMC Pediatrics;18:332, Journal article; Journal article; Peer reviewed, 2018-10-19)Background: Moldova is ranked as one of the countries in Europe with the lowest income per capita and with a relatively high infant and maternal mortality rate. Information on neurodisabilities in general is limited, and ... -
Challenges in epilepsy – the perspective of Norwegian epilepsy patients
(Acta Neurologica Scandinavica;Volume 140, Issue 1, July 2019, Journal article; Peer reviewed, 2019-04-08)Objectives: For most people with epilepsy (PWE), problems that are not directly related to seizures may constitute major challenges in everyday life. The purpose of this study was to determine the extent of these challenges ... -
Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels
(Journal of ophthalmology;Volume 2022, Article ID 5103231, Peer reviewed; Journal article, 2022-08-03)Purpose. To investigate the changes in the tear cytokine profile of patients with meibomian gland dysfunction (MGD) treated with eyelid warming and to correlate these changes with clinical parameters for dry eye disease ... -
Changes in the use of antiseizure medications in children and adolescents in Norway, 2009–2018
(Epilepsy Research;Volume 181, March 2022, 106872, Peer reviewed; Journal article, 2022-02-15)Background: The use of antiseizure medications (ASMs) in the pediatric population is poorly studied. The purpose of this study was to investigate changes in the use of ASMs in children and adolescents compared to adults, ... -
Characterization of Differentially Expressed miRNAs and Their Predicted Target Transcripts during Smoltification and Adaptation to Seawater in Head Kidney of Atlantic Salmon
(Genes;Volume 11, Issue 9, Journal article; Peer reviewed, 2020-09-08)Smoltification and early seawater phase are critical developmental periods with physiological and biochemical changes in Atlantic salmon that facilitates survival in saltwater. MicroRNAs (miRNAs) are known to have important ... -
Characterization of miRNAs in cultured atlantic salmon head kidney monocyte-like and macrophage-like cells
(International Journal of Molecular Sciences;Volume 21 / Issue 11, Journal article; Peer reviewed, 2020-06-02)Macrophages are among the first cells to respond to infection and disease. While microRNAs (miRNAs) are involved in the process of monocyte-to-macrophage differentiation in mammals, less is known in teleost fish. Here, ... -
Characterization of miRNAs in Embryonic, Larval, and Adult Lumpfish Provides a Reference miRNAome for Cyclopterus lumpus
(Biology;Volume 11 / Issue 1, Peer reviewed; Journal article, 2022-01-13)MicroRNAs (miRNAs) are endogenous small RNA molecules involved in the post-transcriptional regulation of protein expression by binding to the mRNA of target genes. They are key regulators in teleost development, maintenance ... -
Chiral N-benzyl-N-methyl-1-(naphthalen-1-yl)ethanamines and their in vitro antifungal activity against Cryptococcus neoformans, Trichophyton mentagrophytes and Trichophyton rubrum
(European Journal of Medicinal Chemistry;68, Journal article; Peer reviewed, 2013-10)In the search for new antifungal compounds and to explore structure activity relationships, a series of 24 chiral benzyl amine type antifungals was synthesised and characterised. In vitro testing against the human pathogen ... -
Chronic fatigue and depression due to multiple sclerosis: Immune-inflammatory pathways, tryptophan catabolites and the gut-brain axis as possible shared pathways
(Multiple Sclerosis and Related Disorders;Volume 46, November 2020, Journal article; Peer reviewed, 2020-09-28)Chronic fatigue and major depression (MDD)-like symptoms are common manifestations of multiple sclerosis (MS), both with huge impact on quality of life. Depression can manifest itself as fatigue, and depressive symptoms ... -
Chronic hyperglycemia reduces substrate oxidation and impairs metabolic switching of human myotubes
(Biochimica et Biophysica Acta - Molecular Basis of Disease;1812 (1), Journal article; Peer reviewed, 2011-01)Skeletal muscle of insulin resistant individuals is characterized by lower fasting lipid oxidation and reduced ability to switch between lipid and glucose oxidation. The purpose of the present study was to examine if chronic ... -
Cisplatin treatment of testicular cancer patients introduces long-term changes in the epigenome
(Clinical Epigenetics;11, Article number: 179 (2019), Journal article; Peer reviewed, 2019-12-03)Background: Cisplatin-based chemotherapy (CBCT) is part of standard treatment of several cancers. In testicular cancer (TC) survivors, an increased risk of developing metabolic syndrome (MetS) is observed. In this epigenomewide ... -
Classifying Dementia Using Local Binary Patterns from Different Regions in Magnetic Resonance Images
(Journal of Biomedical Imaging;2015, Journal article; Peer reviewed, 2015-03-22)Dementia is an evolving challenge in society, and no disease-modifying treatment exists. Diagnosis can be demanding and MR imaging may aid as a noninvasive method to increase prediction accuracy. We explored the use of ... -
Clinical experience combined with therapeutic drug monitoringof lacosamide
(Acta Neurologica Scandinavica;Volume 141, Issue 4, Journal article; Peer reviewed, 2019-12-14)Objective: Lacosamide (LCM) is an antiepileptic drug (AED) with insufficient clinical experience in patients with intellectual disability (ID). They often have more severe epilepsy with comorbidities. The objective was to ... -
Communicating radiation risk to patients: Experiences among radiographers in Norway
(Journal of Medical Imaging and Radiation Sciences;Volume 51, Issue 4, Supplement, Journal article; Peer reviewed, 2020-07-30)Introduction: Risk communication related to radiation has become more important during the last decade. Informing patients of benefits, risks, and alternative imaging methods is necessary to make informed decisions. The ... -
Comparative Effectiveness and Persistence of SB4 and Reference Etanercept in Patients With Psoriatic Arthritis in Norway
(Arthritis care & research;, Peer reviewed; Journal article, 2024)Objective. We aim to compare drug effectiveness and persistence between the reference etanercept (ETN) and ETN biosimilar SB4 in patients with psoriatic arthritis (PsA) naive to ETN and to investigate drug effectiveness ... -
Comparison of radiation exposure to the patient and contrast detail resolutions across micro dose 2D/3D slot scanner and two conventional digital radiography X-ray imaging systems
(Radiation Protection Dosimetry;Volume 185, Issue 2, November 2019, Journal article; Peer reviewed, 2019-01-29)PURPOSE: To assess and compare the radiation dose and image quality of the low dose 2D/3D EOS slot scanner (LDSS) to conventional digital radiography (DR) X-ray imaging systems for chest and knee examination protocols. METHODS ... -
Competence for Natural Transformation Is Common among Clinical Strains of Resistant Acinetobacter spp
(Microorganisms;Volume 7, Issue 2, Journal article; Peer reviewed, 2019-01-24)Horizontal gene transfer events provide the basis for extensive dissemination of antimicrobial resistance traits between bacterial populations. Conjugation is considered to be the most frequent mechanism behind new resistance ... -
Competence in Sports Pharmacy among Pharmacy Students in Norway
(Peer reviewed; Journal article, 2024)Pharmacists are competent to promote the proper use of medicines. According to the International Pharmaceutical Federation, pharmacists must develop competence in sports pharmacy and the contents of the World Anti-Doping ... -
Complexity of drug substitutions caused by drug tenders: A mixed-methods study in Denmark
(Peer reviewed; Journal article, 2021)Objective: The objective of this study was to investigate factors influencing the complexity of drug substitutions caused by drug tenders in a Danish hospital setting. Methods: A sequential explanatory mixed-methods approach ... -
Complications, reoperations, readmissions, and length of hospital stay in 34 639 surgical cases of lumbar disc herniation
(The Bone & Joint Journal;Volume 101-B, Issue 4 / April 2019, Journal article; Peer reviewed, 2019-03-31)Aims The aims of this study were to determine the rates of surgical complications, reoperations, and readmissions following herniated lumbar disc surgery, and to investigate the impact of sociodemographic factors and ...