Blar i HV - Institutt for naturvitenskapelige helsefag på tittel
Viser treff 158-177 av 407
-
How does botulinum toxin inhibit itch?
(Toxins;Volume 14 / Issue 10, Peer reviewed; Journal article, 2022)Two decades after reports of the anti-pruritic effects of botulinum neurotoxins (BoNTs), there is still no approved product for the anti-itch indication of BoNTs, and most clinical case reports still focus on the off-label ... -
HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization
(Journal article; Peer reviewed, 2017)Sensitive and specific genotyping of human papillomaviruses (HPVs) is important for population-based surveillance of carcinogenic HPV types and for monitoring vaccine effectiveness. Here we compare HPV genotyping by Next ... -
HPV16 and HPV18 type-specific APOBEC3 and integration profiles in different diagnostic categories of cervical samples
(Tumour Virus Research;Volume 12, December 2021, 200221, Peer reviewed; Journal article, 2021-07-14)Human papillomavirus (HPV) 16 and 18 are the most predominant types in cervical cancer. Only a small fraction of HPV infections progress to cancer, indicating that additional factors and genomic events contribute to the ... -
HPV16 whole genome minority variants in persistent infections from young Dutch women
(Journal of Clinical Virology;Volume 119, October 2019, Journal article; Peer reviewed, 2019-08-09)Background: Chronic infections by one of the oncogenic human papillomaviruses (HPVs) are responsible for near 5% of the global cancer burden and HPV16 is the type most often found in cancers. HPV genomes displayunexpected ... -
Human brain organoids in migraine research: Pathogenesis and drug development
(Peer reviewed; Journal article, 2023) -
Human Brain Organoids in the Preclinical Phase of Drug Development for Migraine
(Peer reviewed; Journal article, 2024)Developing drugs for brain disorders poses significant hurdles. These challenges stem from the scarcity of optimal models for preclinical drug testing and the often observed lack of translation from preclinical to human ... -
Hva finnes på innsiden av kranarmaturer?
(Vann;, Journal article; Peer reviewed, 2012)Innsiden av vannkraner kommer i kontakt med både mikrober som er til stede i drikkevann og de som finnes på hender, matrester og i luften. En hypotese er at kranbiofilmer kan være tilholdssted for sykdomsfremkallende ... -
Hvor robust er samsvaret mellom respondering på matching-to-sample tester og sorteringstester?
(Norsk tidsskrift for atferdsanalyse;Nummer 2 (VINTER 2018), Journal article; Peer reviewed, 2018)Formålet med dette eksperimentet var å undersøke om samsvaret mellom resultatene på en matching-to-sample (MTS) test og sorteringstester også er gjeldende ved bruk en Many-to-One (MTO) treningsstruktur. Vi ønsket å gjøre ... -
Hyperactivation of NF-κB via the MEK signaling is indispensable for the inhibitory effect of cAMP on DNA damage-induced cell death.
(Molecular Cancer;10 (45), Journal article; Peer reviewed, 2011-04-21)With cAMP signaling having a profound inhibitory effect on DNA damage-induced apoptosis in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells, understanding how this signaling pathway affects the survival capacity ... -
'I try not to bother the residents too much' - the use of capillary blood glucose measurements in nursing homes
(Journal article; Peer reviewed, 2016)Background Capillary blood glucose measurements are regularly used for nursing home residents with diabetes. The usefulness of these measurements relies on clear indications for use, correct measurement techniques, ... -
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor
(Nature Genetics;Volume 49, Issue 7, Journal article; Peer reviewed, 2017-06-12)Genome-wide association studies (GWAS) have transformed our understanding of testicular germ cell tumour (TGCT) susceptibility but much of the heritability remains unexplained. Here we report a new GWAS, a meta-analysis ... -
Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients—a genome-wide association study adjusting for smoking habits
(Translational Psychiatry; 10, Article number: 198 (2020), Journal article; Peer reviewed, 2020-06-19)Clozapine (CLZ) is the superior antipsychotic drug for treatment of schizophrenia, but exhibits an extensive interpatient pharmacokinetic variability. Here, we conducted a genome-wide association study (GWAS) of CLZ serum ... -
Identification of differentially expressed Atlantic salmon miRNAs responding to salmonid alphavirus (SAV) infection
(Journal article; Peer reviewed, 2017)Background MicroRNAs (miRNAs) control multiple biological processes including the innate immune responses by negative post-transcriptional regulation of gene expression. As there were no studies on the role(s) of miRNAs ... -
Imaging in Lyme neuroborreliosis
(Insight into Imaging;October 2018, Volume 9, Issue 5, Journal article; Peer reviewed, 2018-09-04)Lyme neuroborreliosis (LNB) is a tick-borne spirochetal infection with a broad spectrum of imaging pathology. For individuals who live in or have travelled to areas where ticks reside, LNB should be considered among ... -
Imaging predictors of response to cardiac resynchronization therapy: left ventricular work asymmetry by echocardiography and septal viability by cardiac magnetic resonance
(European Heart Journal;Volume 41, Issue 39, Journal article; Peer reviewed, 2020-09-11)Aims: Left ventricular (LV) failure in left bundle branch block is caused by loss of septal function and compensatory hyperfunction of the LV lateral wall (LW) which stimulates adverse remodelling. This study investigates ... -
Imaging the tumour microenvironment in rectal cancer: Decline in tumour blood flow during radiotherapy predicts good outcome
(Peer reviewed; Journal article, 2023)Background and purpose Measuring rectal tumour response to radiation is pivotal to restaging patients and for possibly stratification to a watch-and-wait strategy. Recognizing the importance of the tumour microenvironment, ... -
The impact of body compositions on contrast medium enhancement in chest CT: a randomised controlled trial
(Peer reviewed; Journal article, 2023)Objective: To compare a fixed-volume contrast medium (CM) protocol with a combined total body weight (TBW) and body composition-tailored protocol in chest CT. Methods and materials: Patients referred for routine contrast ... -
Impact of growing up with somatic long-term health challenges on school completion, NEET status and disability pension: a population-based longitudinal study
(BMC Public Health;21, Article number: 514 (2021), Peer reviewed; Journal article, 2021-03-16)Background: Young adulthood is an important transitional life phase that can determine a person’s educational and employment trajectories. The aim of this study was to examine the impact of somatic long-term health challenges ... -
Impact of hyperfractionated re-irradiation on quality of life in patients with recurrent or second primary head and neck cancer, a prospective single institutional study
(Peer reviewed; Journal article, 2023)Purpose Describe the clinical outcome of hyperfractionated re-irradiation (HFRT) in patients with recurrent or second primary (SP) head and neck cancer (HNC). Methods This prospective observational study included HNC ... -
Impact of initial emotional states and self-efficacy changes on nursing students’ practical skills performance in simulation-based education
(Nursing Reports;Volume 11, Issue 2, Peer reviewed; Journal article, 2021-04-21)Training through simulation has shown to increase relevant and specific skills sets across a wide range of areas in nursing and related professions. Increasing skills has a reciprocal relation to the development of ...