Blar i HV - Master i Biomedisin på utgivelsesdato
Viser treff 81-92 av 92
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Effects of the food processing contaminant acrylamide and its metabolite glycidamide in human neural stem cells undergoing differentiation
(Master thesis, 2021-05)Occupational exposure to the acrylamide (AA) monomer has been known since the 1960s to cause neurotoxicity of the central and peripheral nervous system. Concerns regarding exposure of the general populations arose upon ... -
Change in content of extracellular vesicles from human skeletal muscle cells after electrical pulse stimulation with focus on microRNA.
(Master thesis, 2021-05)3.1 Background and Aim Extracellular vesicles (EVs) are nanoparticles with a double membrane postulated to be released by cells of all types and can be detected in all body fluids. They are classified in three groups ... -
Difference between volume Computed Tomography Dose Index (CTDIvol) and Size-Specific Dose Estimates (SSDE) in abdomen- and thorax protocols in patients of different sizes in different CT scanners
(Master thesis, 2021-05)Background: Volume Computed Tomography Dose Index (CTDIvol) only provides information about the radiation dose delivered by a CT scanner. The Size Specific Dose Estimate (SSDE) introduced by the American Association of ... -
Effects of bromodomain or androgen-receptor inhibitors in combination with radiopharmaceuticals in castration-resistant prostate cancer cell monolayers and multicellular spheroids
(Master thesis, 2021-05)Background: Prostate cancer not responding to androgen deprivation therapy is known as castration-resistant prostate cancer (CRPC). Despite rapid increase of treatment options, the disease remains incurable, when metastases ... -
Undersøkelse av autofagi-nivåer i cellemodeller for dannelse og progresjon av prostatakreft
(Master thesis, 2021-05)Bakgrunn og formål Eksisterende forskning gir ingen klare svar på om autofagi opp- eller nedreguleres i cellens utvikling fra en normal celle til en aggressiv og metastaserende kreftcelle. I mangel på forskning med metoder ... -
Migration of prostate cancer cells along neurite outgrowths: optimalization of experimental conditions and characterization of nerve-cancer co-cultures
(Master thesis, 2021-05)As approximately 5000 males are diagnosed with prostate cancer every year in Norway, prostate cancer persists as a medical issue today. It is shown that tumor innervation is important for development and progression of the ... -
Effekt av kortkjedede fettsyrer og forgreinede fettsyrer på energimetabolisme i skjelettmuskelceller
(Master thesis, 2021-05)Sammendrag Innledning: I det siste har det vært stor fokus på sammenheng mellom tarmflora og etiologien av metabolske sykdommer som fedme og type 2-diabetes. Tarmflora kan spille en viktig rolle i energimetabolisme ved ... -
Behandling av Nevroendokrine Tumorer med 177Lu-DOTATATE - Fra Pasientens Perspektiv
(Master thesis, 2021-05)I 2020 ble det på bakgrunn av en internasjonal beslutning innført peptidreseptor-nuklideterapi med 177Lu-DOTATATE ved fire norske sykehus, som et behandlingsalternativ for pasienter med nevroendokrine tumorer (NETs). For ... -
Optimizing DNA Extraction from Dried Blood Spots for Biological Age Measurements
(Master thesis, 2021-05)While the chronological age is the time that has passed since birth, the biological age is determined by physiological signs of aging. Methylation at CpG sites has proven to be a promising biomarker of biological age, and ... -
"HPV chromosomal integration as a biomarker for cancer progression" Validation and characterization of integration sites in HPV31, 33 and 45 positive cervical samples
(Master thesis, 2021-05)Background: Human papillomavirus (HPV) is associated with 4.5% of all human cancers worldwide including cervical cancer. Cytological and/or HPV primary screening is used to uncover cancer precursors. Still, better clinical ... -
Deep inspiration breath-hold in stereotactic and conventional fractionated radiotherapy of lesions in the lung
(Master thesis, 2021-05)The purpose of the clinical study was to evaluate lung cancer patients’ ability to perform deep inspiration breath-hold (DIBH) during CT simulation and throughout the treatment course of radiation therapy (RT). In addition, ... -
GCN2 as a therapeutic target for prostate cancer
(Master thesis, 2021-08)Background: Prostate cancer (PC) is the second most common cancer in men worldwide. Primary PC is treated by surgery, radiotherapy or high dose-rate brachytherapy and androgen deprivation therapy (ADT) – and this is usually ...