Global fertility in 204 countries and territories, 1950-2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
Bhattacharjee, Natalia V.; Schumacher, Austin E; Aali, Amirali; Abate, Yohannes Habtegiorgis; Abbasgholizadeh, Rouzbeh; Abbasian, Mohammadreza; Abbasi-Kangevari, Mohsen ; Hedayat, Abbastabar; Abd ElHafeez, Samar; Abd-Elsalam, Sherief; Mohammad, Abdollahi; Abdollahifar, Mohammad-Amin; Abdoun, Meriem; Abdullahi, Auwal; Abebe, Mesfin; Shawel Abebe, Samrawit; Abiodun, Olumide; Abolhassani, Hassan; Abolmaali, Meysam; Abouzid, Mohamed; Aboye, Girma Beressa Aboye; Abreu, Lucas Guimarães; Abrha, Woldu Aberhe; Michael R M, Abrigo; Abtahi, Dariush; Abualruz, Hasan; Abubakar, Bilyaminu; Abu-Gharbieh, Eman ; Abu-Rmeileh, Niveen Me; Adal, Tadele Girum; Molla Adane, Mesafint; Atanda Adeagbo Adeagbo, Oluwafemi; Adedoyin, Rufus Adesoji; Victor, Adekanmbi; Aden, Bashir; Adepoju, Abiola Victor; Dadras, Omid; Sagoe, Dominic; Bjørge, Tone; Nauman, Javaid; Khosrowjerdi, Mahmood; Kisa, Adnan; Kisa, Sezer; Pereira, Gavin; Eikemo, Terje Andreas; Zou, Zhiyong; Zyoud, Samer H.; Murray, Christopher J.L.; Smith, Amanda E.; Vollset, Stein Emil
Peer reviewed, Journal article
Published version
Date
2024Metadata
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Original version
10.1016/S0140-6736(24)00550-6Abstract
Background Accurate assessments of current and future fertility—including overall trends and changing population
age structures across countries and regions—are essential to help plan for the profound social, economic,
environmental, and geopolitical challenges that these changes will bring. Estimates and projections of fertility are
necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality, and
family planning and support. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 produced
up-to-date and comprehensive demographic assessments of key fertility indicators at global, regional, and national
levels from 1950 to 2021 and forecast fertility metrics to 2100 based on a reference scenario and key policy-dependent
alternative scenarios.
Methods To estimate fertility indicators from 1950 to 2021, mixed-effects regression models and spatiotemporal
Gaussian process regression were used to synthesise data from 8709 country-years of vital and sample registrations,
1455 surveys and censuses, and 150 other sources, and to generate age-specific fertility rates (ASFRs) for 5-year age
groups from age 10 years to 54 years. ASFRs were summed across age groups to produce estimates of total fertility
rate (TFR). Livebirths were calculated by multiplying ASFR and age-specific female population, then summing across
ages 10–54 years. To forecast future fertility up to 2100, our Institute for Health Metrics and Evaluation (IHME)
forecasting model was based on projections of completed cohort fertility at age 50 years (CCF50; the average number
of children born over time to females from a specified birth cohort), which yields more stable and accurate measures
of fertility than directly modelling TFR. CCF50 was modelled using an ensemble approach in which three sub-models
(with two, three, and four covariates variously consisting of female educational attainment, contraceptive met need,
population density in habitable areas, and under-5 mortality) were given equal weights, and analyses were conducted
utilising the MR-BRT (meta-regression—Bayesian, regularised, trimmed) tool. To capture time-series trends in
CCF50 not explained by these covariates, we used a first-order autoregressive model on the residual term. CCF50 as a
proportion of each 5-year ASFR was predicted using a linear mixed-effects model with fixed-effects covariates (female
educational attainment and contraceptive met need) and random intercepts for geographical regions. Projected TFRs
were then computed for each calendar year as the sum of single-year ASFRs across age groups. The reference forecast
is our estimate of the most likely fertility future given the model, past fertility, forecasts of covariates, and historical
relationships between covariates and fertility. We additionally produced forecasts for multiple alternative scenarios in
each location: the UN Sustainable Development Goal (SDG) for education is achieved by 2030; the contraceptive met
need SDG is achieved by 2030; pro-natal policies are enacted to create supportive environments for those who give
birth; and the previous three scenarios combined. Uncertainty from past data inputs and model estimation was
propagated throughout analyses by taking 1000 draws for past and present fertility estimates and 500 draws for future
forecasts from the estimated distribution for each metric, with 95% uncertainty intervals (UIs) given as the
2·5 and 97·5 percentiles of the draws. To evaluate the forecasting performance of our model and others, we computed
skill values—a metric assessing gain in forecasting accuracy—by comparing predicted versus observed ASFRs from
the past 15 years (2007–21). A positive skill metric indicates that the model being evaluated performs better than the
baseline model (here, a simplified model holding 2007 values constant in the future), and a negative metric indicates
that the evaluated model performs worse than baseline.
Findings During the period from 1950 to 2021, global TFR more than halved, from 4·84 (95% UI 4·63–5·06) to
2·23 (2·09–2·38). Global annual livebirths peaked in 2016 at 142 million (95% UI 137–147), declining to
129 million (121–138) in 2021. Fertility rates declined in all countries and territories since 1950, with TFR remaining
above 2·1—canonically considered replacement-level fertility—in 94 (46·1%) countries and territories in 2021. This
included 44 of 46 countries in sub-Saharan Africa, which was the super-region with the largest share of livebirths
in 2021 (29·2% [28·7–29·6]). 47 countries and territories in which lowest estimated fertility between 1950 and 2021
was below replacement experienced one or more subsequent years with higher fertility; only three of these locations
rebounded above replacement levels. Future fertility rates were projected to continue to decline worldwide, reaching
a global TFR of 1·83 (1·59–2·08) in 2050 and 1·59 (1·25–1·96) in 2100 under the reference scenario. The number of
countries and territories with fertility rates remaining above replacement was forecast to be 49 (24·0%) in 2050 and only six (2·9%) in 2100, with three of these six countries included in the 2021 World Bank-defined low-income group,
all located in the GBD super-region of sub-Saharan Africa. The proportion of livebirths occurring in sub-Saharan Africa
was forecast to increase to more than half of the world’s livebirths in 2100, to 41·3% (39·6–43·1) in 2050 and
54·3% (47·1–59·5) in 2100. The share of livebirths was projected to decline between 2021 and 2100 in most of the
six other super-regions—decreasing, for example, in south Asia from 24·8% (23·7–25·8) in 2021 to 16·7% (14·3–19·1)
in 2050 and 7·1% (4·4–10·1) in 2100—but was forecast to increase modestly in the north Africa and Middle East and
high-income super-regions. Forecast estimates for the alternative combined scenario suggest that meeting SDG
targets for education and contraceptive met need, as well as implementing pro-natal policies, would result in global
TFRs of 1·65 (1·40–1·92) in 2050 and 1·62 (1·35–1·95) in 2100. The forecasting skill metric values for the IHME
model were positive across all age groups, indicating that the model is better than the constant prediction.
Interpretation Fertility is declining globally, with rates in more than half of all countries and territories in 2021 below
replacement level. Trends since 2000 show considerable heterogeneity in the steepness of declines, and only a small
number of countries experienced even a slight fertility rebound after their lowest observed rate, with none reaching
replacement level. Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion
occurring in the lowest-income countries. Future fertility rates will continue to decline worldwide and will remain low
even under successful implementation of pro-natal policies. These changes will have far-reaching economic and
societal consequences due to ageing populations and declining workforces in higher-income countries, combined
with an increasing share of livebirths among the already poorest regions of the world.