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dc.contributor.authorBerger, Sigurd
dc.contributor.authorAndersen, Rune
dc.contributor.authorSmåstuen, Milada Cvancarova
dc.contributor.authorRosseland, Leiv Arne
dc.contributor.authorDorenberg, Eric
dc.date.accessioned2024-01-25T07:57:36Z
dc.date.available2024-01-25T07:57:36Z
dc.date.created2023-03-17T13:04:31Z
dc.date.issued2023
dc.identifier.citationJournal of Plastic, Reconstructive & Aesthetic Surgery. 2023, 77 46-53.en_US
dc.identifier.issn1748-6815
dc.identifier.urihttps://hdl.handle.net/11250/3113681
dc.description.abstractPurpose The aim of this observational study was to assess health-related quality of life (HRQOL) changes in patients with vascular malformations, over a period of almost eight years, and to assess clinical and demographic characteristics possibly associated with HRQOL changes. Methods Eighty out of 111 patients who were included in a previously published comparative HRQOL study accepted inclusion in this follow-up study. HRQOL at baseline and follow-up was assessed with the Short-Form 36-item questionnaire (SF-36). Median observation time was 7.9 years. Linear mixed models and linear regression models were applied to assess HRQOL change and possible associations with demographic and clinical variables. Results The median age of the patient cohort at baseline evaluation (n = 111) was 27.0 years. Ninety-six out of 111 (86.5%) patients were diagnosed with venous malformations. Significantly higher SF-36 scores at follow-up were found for the physical domains Role limitations due to (RLDT) physical problems (difference=13.5; 95% CI [1.6, 25.3]) and Bodily pain (difference=11.3; 95% CI [3.8, 18.8]). No deterioration of HRQOL was found in any domain. In multivariate analyses, female gender, muscle/bone involvement, and higher age were associated with a positive relative change in SF-36 in the domains Physical functioning, RLDT physical problems, and RLDT emotional problems, respectively. Invasive treatment was not associated with long-term HRQOL change. Conclusions Over a period of almost eight years, significant improvement of SF-36 scores was observed in the physical domains RLDT physical problems and bodily pain. Female gender, muscle/bone involvement, and higher age were associated with HRQOL improvement in certain domains.en_US
dc.language.isoengen_US
dc.relation.urihttps://reader.elsevier.com/reader/sd/pii/S1748681522005770?token=E1A6306DA385E88EE1DF315D88A23BE15D126DC33AEB1555830ECE0654CF6DC401F08AD2F2C91B1DFA3302C4D040A54D&originRegion=eu-west-1&originCreation
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleLong-term changes of health-related quality of life in patients with peripheral vascular malformations – a prospective observational studyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.doi10.1016/j.bjps.2022.10.024
dc.identifier.cristin2134781
dc.source.journalJournal of Plastic, Reconstructive & Aesthetic Surgeryen_US
dc.source.volume77en_US
dc.source.pagenumber46-53en_US


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal