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dc.contributor.authorIndrekvam, Kari
dc.contributor.authorBånerud, Ingrid Fjeldheim
dc.contributor.authorHermansen, Erland
dc.contributor.authorAustevoll, Ivar Magne
dc.contributor.authorRekeland, Frode Gurvin
dc.contributor.authorGuddal, Maren Hjelle
dc.contributor.authorSolberg, Tore
dc.contributor.authorBrox, Jens Ivar
dc.contributor.authorHellum, Christian
dc.contributor.authorStorheim, Kjersti
dc.identifier.citationEuropean spine journal. 2023, .en_US
dc.description.abstractPurpose To provide an overview of the The Norwegian Degenerative spondylolisthesis and spinal stenosis (NORDSTEN)- study and the organizational structure, and to evaluate the study population. Methods The NORDSTEN is a multicentre study with 10 year follow-up, conducted at 18 public hospitals. NORDSTEN includes three studies: (1) The randomized spinal stenosis trial comparing the impact of three different decompression techniques; (2) the randomized degenerative spondylolisthesis trial investigating whether decompression surgery alone is as good as decompression with instrumented fusion; (3) the observational cohort tracking the natural course of LSS in patients without planned surgical treatment. A range of clinical and radiological data are collected at defined time points. To administer, guide, monitor and assist the surgical units and the researchers involved, the NORDSTEN national project organization was established. Corresponding clinical data from the Norwegian Registry for Spine Surgery (NORspine) were used to assess if the rand- omized NORDSTEN-population at baseline was representative for LSS patients treated in routine surgical practice. Results A total of 988 LSS patients with or without spondylolistheses were included from 2014 to 2018. The clinical trials did not find any difference in the efficacy of the surgical methods evaluated. The NORDSTEN patients were similar to those being consecutively operated at the same hospitals and reported to the NORspine during the same time period. Conclusion The NORDSTEN study provides opportunity to investigate clinical course of LSS with or without surgical interventions. The NORDSTEN-study population were similar to LSS patients treated in routine surgical practice, support- ing the external validity of previously published results.en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titleThe Norwegian degenerative spondylolisthesis and spinal stenosis (NORDSTEN) study: study overview, organization structure and study populationen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.source.journalEuropean spine journalen_US

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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal