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  • TKD - Department of Mechanical, Electronics and Chemical Engineering
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Measurements of physical forces in cancer cells

Lillebø, Emma; Mong Vu, Thu Linda
Bachelor thesis
Published version
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P1_Lillebø_og_Mong_Vu.pdf (7.800Mb)
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https://hdl.handle.net/11250/2999700
Utgivelsesdato
2022
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  • TKD - Department of Mechanical, Electronics and Chemical Engineering [131]
Sammendrag
A broader knowledge on how cancer cells behave physically is important for understanding how they

spread throughout the body. In order to understand how metastasis of cancer cells really works, it is

necessary to know what happens with physical forces when cancer cells are awakened from

quiescence.

Cancer cells, isolated from three patients with urinary bladder cancer, were analyzed with live cell

imaging and traction force microscopy.

The cancer cell lines showed common features when it comes to traction forces arising after exit from

quiescence and activation of cell migration. However, different migration patterns, in terms of single-

cell and collective migration, as well as different migration velocities were observed.
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OsloMet-Storbyuniversitetet

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