Blar i Publikasjoner fra Cristin på forfatter "Utheim, Tor Paaske"

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    • Artificial intelligence in dry eye disease 

      Storås, Andrea Marheim; Strumke, Inga; Riegler, Michael Alexander; Grauslund, Jakob; Hammer, Hugo Lewi; Yazidi, Anis; Halvorsen, Pål; Gundersen, Kjell Gunnar; Utheim, Tor Paaske; Jackson, Catherine Joan (The ocular surface;Volume 23, January 2022, Peer reviewed; Journal article, 2021-12-01)
      Dry eye disease (DED) has a prevalence of between 5 and 50%, depending on the diagnostic criteria used and population under study. However, it remains one of the most underdiagnosed and undertreated conditions in ophthalmology. ...

    • The association between visual display terminal use and dry eye: a review 

      Fjærvoll, Haakon Kristoffer Olsen; Fjærvoll, Ketil Andreas Olsen; Magnø, Morten Scherven; Moschowits, Emily; Vehof, Jelle; Dartt, Darlene A.; Utheim, Tor Paaske (Acta Ophthalmologica;, Peer reviewed; Journal article, 2021-10-25)
      Background. Dry eye disease (DED) is a multifactorial disease of the tear film and ocular surface. It causes ocular symptoms, reduced quality of life and a considerable economic burden on society. Prolonged use of visual ...

    • Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels 

      Landsend, Erlend Christoffer Sommer; Olafsson, Jonatan; Lai, Xiaoran; Aass, Hans Christian Dalsbotten; Utheim, Tor Paaske (Journal of ophthalmology;Volume 2022, Article ID 5103231, Peer reviewed; Journal article, 2022-08-03)
      Purpose. To investigate the changes in the tear cytokine profile of patients with meibomian gland dysfunction (MGD) treated with eyelid warming and to correlate these changes with clinical parameters for dry eye disease ...

    • Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients 

      Naqvi, Maria; Fineide, Fredrik; Utheim, Tor Paaske; Charnock, Colin (Peer reviewed; Journal article, 2024)
      Purpose: The purpose of this study was to investigate the ocular microbiome in individuals with dry eye disease and to identify features of their ocular microbiome of possible health and diagnostic significance. Methods: ...

    • Identifying Important Proteins in Meibomian Gland Dysfunction with Explainable Artificial Intelligence 

      Storås, Andrea; Magnø, Morten Schjerven; Fineide, Fredrik; Thiede, Bernd; Chen, Xiangjun; Strumke, Inga; Halvorsen, Pål; Utheim, Tor Paaske; Riegler, Michael Alexander (Peer reviewed; Journal article, 2023)
      Meibomian gland dysfunction is the most common cause of dry eye disease and leads to significantly reduced quality of life and social burdens. Because meibomian gland dysfunction results in impaired function of the tear ...

    • In-office thermal systems for the treatment of dry eye disease 

      Beining, Marie Wangen; Magnø, Morten Scherven; Moschowits, Emily; Olafsson, Jonatan; Vehof, Jelle; Dartt, Darlene Ann; Utheim, Tor Paaske (Survey of ophthalmology;Volume 67, Issue 5, September–October 2022, Peer reviewed; Journal article, 2022-08-12)
      Dry eye disease affects millions of people worldwide, causing pain, vision disturbance, and reduced productivity. Meibomian gland dysfunction, a major cause of dry eye, is characterized by chronic glandular inflammation, ...

    • Perturbation of astroglial Slc38 glutamine transporters by NH4 + contributes to neurophysiologic manifestations in acute liver failure 

      Hamdani, El Hassan; Popek, Mariusz; Frontczak-Baniewicz, Małgorzata; Utheim, Tor Paaske; Albrecht, Jan; Zielińska, Magdalena; Chaudhry, Farrukh Abbas (Wiley Open Access;Volume 35, Issue 7, Peer reviewed; Journal article, 2021-06-24)
      Ammonia is considered the main pathogenic toxin in hepatic encephalopathy (HE). However, the molecular mechanisms involved have been disputed. As altered glutamatergic and GABAergic neurotransmission has been reported in ...

    • A Preservative-Free Approach – Effects on Dry Eye Signs and Symptoms After Cataract Surgery 

      Jensen, Per Graae; Nilsen, Christian; Gundersen, Morten; Gundersen, Kjell Gunnar; Potvin, Rick; Gazerani, Parisa; Chen, Xiangjun; Utheim, Tor Paaske; Utheim, Øygunn Aass (Peer reviewed; Journal article, 2024)
      Purpose: To compare the effect of treatment with preservative-free dexamethasone, NSAIDs and trehalose/hyaluronic acid eye drops with the preservative benzalkonium chloride containing dexamethasone and NSAIDs after cataract ...

    • Prevalence of Dry Eye Disease Among Individuals Scheduled for Cataract Surgery in a Norwegian Cataract Clinic 

      Graae Jensen, Per; Gundersen, Morten; Nilsen, Christian; Gundersen, Kjell Gunnar; Potvin, Rick; Gazerani, Parisa; Chen, Xiangjun; Utheim, Tor Paaske; Utheim, Øygunn Aass (Clinical Ophthalmology;, Peer reviewed; Journal article, 2023)
      Purpose: To determine the prevalence of dry eye disease (DED) in patients scheduled for cataract surgery in a Norwegian eye clinic. Patients and Methods: 218 patients scheduled for cataract surgery were examined for DED ...

    • Review on the possible pathophysiological mechanisms underlying visual display terminal-associated dry eye disease 

      Fjærvoll, Ketil Andreas Olsen; Fjærvoll, Haakon Kristoffer Olsen; Magnø, Morten Scherven; Tellefsen Nøland, Sara Julie Maria; Dartt, Darlene Ann; Vehof, Jelle; Utheim, Tor Paaske (Acta Ophthalmologica;, Peer reviewed; Journal article, 2022-04-19)
      Background: Visual display terminal (VDT) use is a key risk factor for dry eye disease (DED). Visual display terminal (VDT) use reduces the blink rate and increases the number of incomplete blinks. However, the exact ...

    • The therapeutic benefits of nanoencapsulation in drug delivery to the anterior segment of the eye: A systematic review 

      Bandhari, Madhavi; Nguyen, Sanko; Yazdani, Mazyar; Utheim, Tor Paaske; Hagesæther, Ellen (Frontiers in Pharmacology;May 2022 | Volume 13 | Article 903519, Peer reviewed; Journal article, 2022-05-13)
      Background: Although numerous nanoparticle formulations have been developed for ocular administration, concerns are being raised about a possible mismatch between potential promises made by the field of nanoparticle research ...

    • The Therapeutic Benefits of Nanoencapsulation in Drug Delivery to the Anterior Segment of the Eye: A Systematic Review 

      Bhandari, Madhavi; Nguyen, Sanko; Yazdani, Mazyar; Utheim, Tor Paaske; Hagesæther, Ellen (Frontiers in Pharmacology;May 2022 | Volume 13 | Article 903519, Peer reviewed; Journal article, 2022)
      Background: Although numerous nanoparticle formulations have been developed for ocular administration, concerns are being raised about a possible mismatch between potential promises made by the field of nanoparticle research ...