• Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells 

      Guerriero, Ilaria; Ramberg, Håkon Andre; Sagini, Krizia; Ramirez-Garrastacho, Manuel; Tasken, Kristin Austlid; Llorente, Alicia (PLOS ONE;16 (6): e0253828, Peer reviewed; Journal article, 2021-06-30)
      The β2-adrenergic receptor has been shown to be involved in neuroendocrine differentiation and to contribute to the development of aggressive prostate cancer. In this study we have investigated whether miR-196a plays a ...
    • Lipid Biomarkers in Liquid Biopsies: Novel Opportunities for Cancer Diagnosis 

      Sagini, Krizia; Urbanelli, Lorena; Buratta, Sandra; Emiliani, Carla; Llorente, Alicia (Peer reviewed; Journal article, 2023)
      Altered cellular metabolism is a well-established hallmark of cancer. Although most studies have focused on the metabolism of glucose and glutamine, the upregulation of lipid metabolism is also frequent in cells undergoing ...
    • siRNA screening reveals that SNAP29 contributes to exosome release 

      Hessvik, Nina Pettersen; Sagini, Krizia; Romero, Silvana Angelica Troncoso; Ramirez, Manuel; Rodriguez, Marta; Tutturen, Astrid Elisabeth Voorham; Kvalvaag, Audun Sverre Myrset; Stang, Espen; Brech, Andreas; Sandvig, Kirsten; Llorente, Alicia (Peer reviewed; Journal article, 2023)
      Cells release extracellular vesicles (EVs) of different sizes. Small EVs (< 200 nm) can originate from the fusion of multive- sicular bodies with the plasma membrane, i.e. exosomes, and from budding of the plasma membrane, ...