HV - Institutt for naturvitenskapelige helsefag: Recent submissions
Now showing items 21-40 of 392
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The alginate polymer OligoG alters susceptibility of biofilm-embedded non-typeable Haemophilus influenzae to ampicillin and ciprofloxacin
(Peer reviewed; Journal article, 2023)Objectives Treatment of respiratory infections with non-typeable Haemophilus influenzae (NTHi) in COPD patients is complicated by biofilm formation, protecting the bacteria against the hosts’ immune response and antibiotics. ... -
A protocol for the development and validation of a virtual reality-based clinical test of social cognition
(Peer reviewed; Journal article, 2023)Background Impairments in social cognition are common after traumatic brain injury (TBI) and may have severe negative consequences for patients and their families. Most tests of social cognition have limited ecological ... -
Patient involvement and expectations during CT scans. Tinkering to involve patients and offer care in radiographic practice
(Peer reviewed; Journal article, 2023)ntroduction: This study investigated how patients expected and experienced to be put first and cared for in diagnostic imaging settings and how putting the patient first was operationalized in practice. Methods: A ... -
Ultra-low-dose emergency chest computed tomography protocols in three vendors: A technical note
(Peer reviewed; Journal article, 2023)Background: In suspected community-acquired pneumonia (CAP), chest CT is superior to the routinely obtained radiographs (CXR), but administers higher radiation doses. However, ultra-low-dose CT (ULDCT) has shown ... -
Microbial dynamics with CRC progression: a study of the mucosal microbiota at multiple sites in cancers, adenomatous polyps, and healthy controls
(Peer reviewed; Journal article, 2023)Accumulating evidence has related the gut microbiota to colorectal cancer (CRC). Fusobacterium nucleatum has repeatedly been linked to colorectal tumorigenesis. The aim of this study was to investigate microbial composition ... -
The Discovery and Characterization of Conserved and Novel miRNAs in the Different Developmental Stages and Organs of Pikeperch (Sander lucioperca)
(Peer reviewed; Journal article, 2024)Micro RNAs (miRNAs) are short non-coding RNAs that act as post-transcriptional gene expression regulators. Genes regulated in vertebrates include those affecting growth and development or stress and immune response. ... -
The efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-up
(Peer reviewed; Journal article, 2023)Objective: To evaluate the efficacy of strength exercise or aerobic exercise compared to usual care on knee-related quality of life (QoL) and knee function at 4 months and 1 year in individuals with knee osteoarthritis. ... -
Competence in Sports Pharmacy among Pharmacy Students in Norway
(Peer reviewed; Journal article, 2024)Pharmacists are competent to promote the proper use of medicines. According to the International Pharmaceutical Federation, pharmacists must develop competence in sports pharmacy and the contents of the World Anti-Doping ... -
Prediction of CYP2D6 poor metabolizers by measurements of solanidine and metabolites—a study in 839 patients with known CYP2D6 genotype
(Peer reviewed; Journal article, 2023)Purpose Poor metabolizers (PMs) of the highly polymorphic enzyme CYP2D6 are usually at high risk of adverse effects during standard recommended dosing of CYP2D6-metabolized drugs. We studied if the metabolism of solanidine, ... -
Is a Single Nephrographic Phase Computed Tomography Sufficient for Detecting Urothelial Carcinoma in Patients with Visible Haematuria? A Prospective Paired Noninferiority Comparison
(Peer reviewed; Journal article, 2023)Background: There is uncertainty about the utility of multiphase computed tomog- raphy (CT) compared with single-phase CT in the routine examination of patients with visible haematuria (VH). Objective: To compare the ... -
Effect of a one-year personalized intensive dietary intervention on body composition in colorectal cancer patients: Results from a randomized controlled trial
(Peer reviewed; Journal article, 2023)Background and aims Changes in body composition may affect colorectal cancer (CRC) patient's risk of cancer recurrence, secondary cancer, and other chronic diseases. The suggested interventions for changes in body composition ... -
Exploring patients' adherence to antibiotics by understanding their health knowledge and relational communication in encounters with pharmacists and physicians
(Peer reviewed; Journal article, 2023)Background: Antibiotics are drugs essential for the treatment of bacterial infections. Widespread and often improper use of antibiotics are driving the emergence of antimicrobial resistance (AMR) globally. A better ... -
A Salutogenic Approach for Collaboration in Health and Technology
(Chapter, 2023)Through collaboration, health services and health-promoting environments can be influenced by patients, health professionals, and stakeholders. Antonovsky’s concept of salutogenesis includes the promotion of a sense of ... -
Evidence for solanidine as a dietary CYP2D6 biomarker: Significant correlation with risperidone metabolism
(Peer reviewed; Journal article, 2023)Aims: The extensive variability in cytochrome P450 2D6 (CYP2D6) metabolism is mainly caused by genetic polymorphisms. However, there is large, unexplained variability in CYP2D6 metabolism within CYP2D6 genotype subgroups. ... -
Is Burning Mouth Syndrome Associated with Extraoral Dryness? A Systematic Review
(Peer reviewed; Journal article, 2023)Burning mouth syndrome (BMS) is characterized by a persistent intraoral burning sensation, often experienced by postmenopausal women. The etiology of BMS remains partially understood, and consequently, treatments remain ... -
Automatic Unsupervised Clustering of Videos of the Intracytoplasmic Sperm Injection (ICSI) Procedure
(Chapter; Conference object, 2023)The in vitro fertilization procedure called intracytoplasmic sperm injection can be used to help fertilize an egg by injecting a single sperm cell directly into the cytoplasm of the egg. In order to evaluate, refine and ... -
Menopausal hormone therapy, oral contraceptives and risk of chronic low back pain: the HUNT Study
(Peer reviewed; Journal article, 2023)Background There are indications that use of menopausal hormone therapy (MHT) and oral contraceptives (OC) increases the risk of low back pain (LBP), with higher oestrogen levels involved in the underlying mechanisms. ... -
Imaging the tumour microenvironment in rectal cancer: Decline in tumour blood flow during radiotherapy predicts good outcome
(Peer reviewed; Journal article, 2023)Background and purpose Measuring rectal tumour response to radiation is pivotal to restaging patients and for possibly stratification to a watch-and-wait strategy. Recognizing the importance of the tumour microenvironment, ... -
Pro-arrhythmic effect of escitalopram and citalopram at serum concentrations commonly observed in older patients – a study based on a cohort of 19,742 patients
(Peer reviewed; Journal article, 2023)Background For a decade, patients have been advised against using high citalopram- and escitalopram-doses due to risk for ventricular arrhythmia and cardiac arrest. Still, these drugs are widely used to treat depression ...