Browsing HV - Institutt for naturvitenskapelige helsefag by Document Types "Peer reviewed"
Now showing items 1-20 of 406
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2-Substituted agelasine analogs : synthesis and biological activity, and structure and reactivity of synthetic intermediates
(Pure and Applied Chemistry;83 (3), Journal article; Peer reviewed, 2011-01-25)2-Substituted N-methoxy-9-methyl-9H-purin-6-amines were synthesized either from their corresponding 6-chloro-9-methyl-9H-purines or 2-chloro-N-methoxy-9-methyl- 9H-purin-6-amine. Great diversity in the amino/imino tautomeric ... -
Accreditation and Power - A discourse analysis of a new regime of governance in higher education
(Scandinavian journal of educational research;iFirst, Journal article; Peer reviewed, 2011-12-19)This article studies discourses within the accreditation of Norwegian higher education conducted by the Norwegian Agency for Quality Assurance in Education (NOKUT), using one concrete case (the accreditation of bachelor ... -
Activity of 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines to Tetrahymena
(Bioorganic chemistry;, Journal article; Peer reviewed, 2012-06-05)A series 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines (43 compounds), some of which are epidermal growth 22 factor tyrosine kinase inhibitors, were tested for their protozoal toxicity using an environmental Tetrahy- 23 mena ... -
Agar og fosfat – ikke så skjønn forening
(Peer reviewed; Journal article, 2023)Bakgrunn: Varmesterilisering av agar og andre geleringsmidler vil i nærvær av fosfat resultere i produksjon av hydrogenperoksid (H2O2) og sannsynligvis andre reaktive oksygenforbindelser (ROS). Disse stoffene begrenser ... -
Age of onset for increased dose-adjusted serum concentrations of antidepressants and association with sex and genotype: An observational study of 34,777 individuals
(European Journal of Clinical Pharmacology;, Peer reviewed; Journal article, 2024)Purpose: The aim of this study was to examine the age of onset for increased dose-adjusted serum concentrations (C/D ratio) of common antidepressant drugs and to explore the potential association with sex and CYP2C19/CYP2D6 ... -
Age prediction in sub-adults based on MRI segmentation of 3rd molar tissue volumes
(Peer reviewed; Journal article, 2023)Purpose Our aim was to investigate tissue volumes measured by MRI segmentation of the entire 3rd molar for prediction of a sub-adult being older than 18 years. Material and method We used a 1.5-T MR scanner with a ... -
The alginate polymer OligoG alters susceptibility of biofilm-embedded non-typeable Haemophilus influenzae to ampicillin and ciprofloxacin
(Peer reviewed; Journal article, 2023)Objectives Treatment of respiratory infections with non-typeable Haemophilus influenzae (NTHi) in COPD patients is complicated by biofilm formation, protecting the bacteria against the hosts’ immune response and antibiotics. ... -
Amide proton transfer-weighted MRI in the clinical setting – correlation with dynamic susceptibility contrast perfusion in the post-treatment imaging of adult glioma patients at 3T
(Radiography;Volume 28, Issue 1, Peer reviewed; Journal article, 2021-01-07)Introduction: We investigated the correlation between amide proton transfer-weighted magnetic resonance imaging (APTw MRI) and dynamic susceptibility contrast (DSC) perfusion in order to assess the potential of APTw MRI ... -
Amplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia
(Journal article; Peer reviewed, 2023)Objective. In gout, hyperuricemia promotes urate crystal deposition, which stimulates the NLRP3 inflammasome and interleukin-1β (IL-1β)–mediated arthritis. Incident gout without background hyperuricemia is rarely reported. ... -
Amyloid-β PET—Correlation with cerebrospinal fluid biomarkers and prediction of Alzheimer´s disease diagnosis in a memory clinic
(PLoS ONE;14(8): e0221365, Journal article; Peer reviewed, 2019-08-05)Background: Alzheimer’s disease (AD) remains a clinical diagnosis but biomarkers from cerebrospinal fluid (CSF) and more lately amyloid imaging with positron emission tomography (PET), are important to support a diagnosis ... -
An analysis of the validity and reliability of handheld ultrasound device for measuring rectus femoris muscle size
(Peer reviewed; Chapter, 2016)Background: Previous studies show that ultrasound is valid and reliable when measuring muscle size. A Philips handheld ultrasound device was released in April 2015. The aim of this study was to investigate the validity ... -
An in vitro study of mucoadhesion and biocompatibility of polymer coated liposomes on HT29-MTX mucus-producing cells
(Journal article; Peer reviewed, 2016)Drug delivery to the oral cavity poses a significant challenge due to the short residence time of the formulations at the site of action. From this point of view, nanoparticulate drug delivery systems with ability to adhere ... -
Analysis of image quality and effective dose in adult chest phantom radiography with high BMI.
(OPTIMAX 2017: Radiation dose, image quality optimisation, the use of new technology in medical imaging;, Chapter; Peer reviewed, 2018)Aim: To investigate the impact of different kVp and mAs values on effective dose and image quality using a chest phantom that simulates a normal sized and an obese patient. Methods and materials: A chest phantom with ... -
Antiepileptic and antidepressive polypharmacy in patients with multiple sclerosis.
(Multiple sclerosis international;2015, Journal article; Peer reviewed, 2015)Objective. Patients with multiple sclerosis (MS) are often suffering from neuropathic pain. Antiepileptic drugs (AEDs) and tricyclic antidepressants (TCAs) are commonly used and are susceptible to be involved in drug ... -
Antimicrobial stewardship: a qualitative study of the development of national guidelines for antibiotic use in hospitals
(Journal article; Peer reviewed, 2017)Background As effective antibiotics are becoming a scarce resource, governmental regulation is needed to promote responsible use. Implementation of antibiotic stewardship and practice guidelines in health care facilities ... -
Apparent diffusion coefficient values in Modic changes – interobserver reproducibility and relation to Modic type
(BMC Musculoskeletal Disorders;23, Article number: 695 (2022), Peer reviewed; Journal article, 2022-07-22)Background: Modic Changes (MCs) in the vertebral bone marrow were related to back pain in some studies but have uncertain clinical relevance. Difusion weighted MRI with apparent difusion coefcient (ADC)-measurements can ... -
Apremilast for genital erosive lichen planus in women (the AP-GELP Study): study protocol for a randomised placebo-controlled clinical trial
(Trials;22, Article number: 469 (2021), Peer reviewed; Journal article, 2021-07-20)Background: Genital erosive lichen planus (GELP) is a genital subtype of lichen planus, a chronic autoimmune inflammatory disease of unknown aetiology. In women, GELP is characterised by painful vulvo-vaginal mucosal ... -
Are physical measures good indicators of image quality at low dose levels? A pilot study
(Chapter; Peer reviewed, 2016)Purpose: To evaluate if physical measures of noise predict image quality at high and low noise levels. Method: Twenty-four images were acquired on a DR system using a Pehamed DIGRAD phantom ... -
Artificial intelligence in the fertility clinic: status, pitfalls and possibilities
(Human Reproduction;Volume 36, Issue 9, Peer reviewed; Journal article, 2021-07-29)In recent years, the amount of data produced in the field of assisted reproduction technology [ART] has increased exponentially. The diversity of data is large, ranging from videos to tabular data. At the same time, ...