Blar i HV - Institutt for naturvitenskapelige helsefag på emneord "Metabolisms"
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The effect of toll-like receptor ligands on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells
(Scientific Reports;11, Article number: 24219 (2021), Peer reviewed; Journal article, 2021-12-20)Skeletal muscle plays an important role in glycaemic control and metabolic homeostasis, making it a tissue of interest with respect to type 2 diabetes mellitus. The aim of the present study was to determine if ligands of ... -
Effects of a Novel UGT2B Haplotype and UGT1A4*3 Allele Variants on Glucuronidation of Clozapine In vivo
(Current drug metabolism;Volume 23, Issue 1, Peer reviewed; Journal article, 2022)Background: Glucuronidation is an important metabolic pathway of clozapine (CLZ), but the impact of various uridine 5'diphospho-glucuronosyltransferases (UGT) polymorphisms on the exposure and metabolism of CLZ in vivo is ...