Browsing HV - Master i Biomedisin by Author "Stokke, Trond"
Now showing items 1-2 of 2
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Establishment and characterization of cell lines to study the proxymitome of the Centrosome and Spindle Pole-associated protein 1
Irakoze, Christa (Master thesis, 2021)The predominantly expressed isoform of CSPP1, CSPP-L, is a centrosomal and Centriolar satellite protein with functions in microtubule organization in cell division and cilia formation. CSPP-L dose and microtubule organizing ... -
Synthetic lethality by inhibition of PARP in ATM-deficient lymphoid cells : reduced proliferation, replication induced DNA damage, G2 delay and cell death
Rein, Idun Dale (Master thesis, 2012)Cells that are deficient in proteins involved in homologous recombination repair (HRR) have been shown to be hypersensitive to PARP inhibitors. While a cell may tolerate PARP inhibition or HRR defects alone, the combination ...