The effect on subjective satiety sensation after intake of dietary fat of different quality

Abstract

Background: The prevalence of overweight and obesity in society is increasing worldwide and it is one of the biggest public health issues today. Recent studies suggest that different dietary fatty acids can affect hunger and satiety signaling. The aim of the present study was to investigate how a test meal with different fat quality, either high in PUFA or SFA, affected subjective satiety sensation and glucose response in healthy individuals. In addition, measure the repeatability of a self-reported satiety sensation questionnaire.

Method: 21 healthy, normal weight individuals completed this double blinded postprandial crossover intervention study; 18 women and 3 men. The participants consumed two different muffins, either high in SFA or PUFA, at four visits (V1 – V4), and filled out a visual analogue scale (VAS) fasted, and at seven time points within 180 minutes at each visit. Blood glucose was measured at the same time intervals as VAS. Wilcoxon sign rank test and Bland Altman Plot were used to compare effects and repeatability between the meals.

Results: This study show no significant differences in how participants perceived satiety after intake of SFA compared to PUFA, using VAS. When studying the repeatability of VAS, we found no significant differences in subjective satiety between the two periods after intake of SFA. After intake of PUFA, we observed a significant difference in sensations for food cravings and desire to eat sugary foods. We observed no effect on postprandial glycemic response after intake of SFA compared to PUFA.

Conclusion: Fat quality in one meal did not affect subjective satiety sensation and glycemic response in healthy subjects postprandially. However, VAS had an overall good repeatability in subjective satiety sensations after intake of the same test meal at two different occasions, indicating that VAS in general could be used as a measure of subjective satiety sensation.