Review Article An evaluation of SAFIRE s potential to reduce the dose received by paediatric patients undergoing CT: a narrative review
Borge, Synnøve Devik; Campbell, Nina; Gomes, Ana; Raszkowski, Aysha Malgorzata; Rook, Jan willem; Sanderud, Audun; Vallinga, Anique; Vouillamoz, Audrey; Buissink, Carst
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https://hdl.handle.net/10642/2801Utgivelsesdato
2015-04-24Metadata
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Borge, S., Campbell, N., Gomes, A., Raszkowski, A. M., Rook, J. W., Sanderud, A., ... & Buissink, C. (2015). An evaluation of SAFIRE’s potential to reduce the dose received by paediatric patients undergoing CT: a narrative review. http://usir.salford.ac.uk/34439/Sammendrag
Introduction: The purpose of this review is to gather and analyse current research publications to
evaluate Sinogram-Affirmed Iterative Reconstruction (SAFIRE). The aim of this review is to investigate
whether this algorithm is capable of reducing the dose delivered during CT imaging while maintaining
image quality. Recent research shows that children have a greater risk per unit dose due to increased
radiosensitivity and longer life expectancies, which means it is particularly important to reduce the
radiation dose received by children.
Discussion: Recent publications suggest that SAFIRE is capable of reducing image noise in CT images,
thereby enabling the potential to reduce dose. Some publications suggest a decrease in dose, by up to
64% compared to filtered back projection, can be accomplished without a change in image quality.
However, literature suggests that using a higher SAFIRE strength may alter the image texture, creating
an overly ‘smoothed’ image that lacks contrast. Some literature reports SAFIRE gives decreased low
contrast detectability as well as spatial resolution. Publications tend to agree that SAFIRE strength three
is optimal for an acceptable level of visual image quality, but more research is required. The importance
of creating a balance between dose reduction and image quality is stressed. In this literature review
most of the publications were completed using adults or phantoms, and a distinct lack of literature for
paediatric patients is noted.
Conclusion: It is necessary to find an optimal way to balance dose reduction and image quality. More
research relating to SAFIRE and paediatric patients is required to fully investigate dose reduction
potential in this population, for a range of different SAFIRE strengths.