Browsing ODA Open Digital Archive by Author "Rundblad, Amanda"
Now showing items 1-10 of 10
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Dietary fat quality, plasma atherogenic lipoproteins, and atherosclerotic cardiovascular disease: An overview of the rationale for dietary recommendations for fat intake
Christensen, Jacob J.; Arnesen, Erik Kristoffer; Rundblad, Amanda; Telle-Hansen, Vibeke; Narverud, Ingunn; Blomhoff, Rune; Bogsrud, Martin Prøven; Retterstøl, Kjetil; Ulven, Stine Marie; Holven, Kirsten Bjørklund (Peer reviewed; Journal article, 2023)The scientific evidence supporting the current dietary recommendations for fat quality keeps accumulating; however, a paradoxical distrust has taken root among many researchers, clinicians, and in parts of the general public. ... -
Differences in peripheral blood mononuclear cell gene expression and triglyceride composition in lipoprotein subclasses in plasma triglyceride responders and non-responders to omega-3 supplementation
Rundblad, Amanda; Larsen, Sunniva; Myhrstad, Mari; Ottestad, Inger; Thoresen, Magne; Holven, Kirsten Bjørklund; Ulven, Stine Marie (Genes and Nutrition;14, Article number: 10 (2019), Journal article; Peer reviewed, 2019-03-20)Background:Intake of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)reduces fasting triglyceride (TG) levels and may thereby lower cardiovascular disease risk. However, there are ... -
Effects of fish and krill oil on gene expression in peripheral blood mononuclear cells and circulating markers of inflammation: a randomised controlled trial
Rundblad, Amanda; Holven, Kirsten Bjørklund; Bruheim, Inge; Myhrstad, Mari; Ulven, Stine Marie (Journal of Nutritional Science;Volume 7, 2018, Journal article; Peer reviewed, 2018-03-21)Marine n-3 (omega-3) fatty acids alter gene expression by regulating the activity of transcription factors. Krill oil is a source of marine n-3 fattyacids that has been shown to modulate gene expression in animal studies; ... -
Effects of krill oil and lean and fatty fish on cardiovascular risk markers: a randomised controlled trial
Rundblad, Amanda; Holven, Kirsten Bjørklund; Bruheim, Inge; Myhrstad, Mari; Ulven, Stine Marie (Journal article; Peer reviewed, 2018)Fish consumption and supplementation with n-3 fatty acids reduce CVD risk. Krill oil is an alternative source of marine n-3 fatty acids and few studies have investigated its health effects. Thus, we compared krill oil ... -
Glycated proteins, glycine, acetate, and monounsaturated fatty acids may act as new biomarkers to predict the progression of type 2 diabetes: Secondary analyses of a randomized controlled trial
Canet, Francisco; Christensen, Jacob J.; Victor, Victor M.; Hustad, Kristin Solheim; Ottestad, Inger; Rundblad, Amanda; Sæther, Thomas; Dalen, Knut Tomas; Ulven, Stine Marie; Holven, Kirsten Bjørklund; Telle-Hansen, Vibeke (Nutrients;Volume 14 / Issue 23, Peer reviewed; Journal article, 2022-12-05)Food protein or food-derived peptides may regulate blood glucose levels; however, studies have shown inconsistent results. The aim of the present study was to characterize subgroups of individuals with increased risk of ... -
Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with Metabolic Syndrome - A SYSDIET Sub-Study
Myhrstad, Mari; De Mello, Vanessa D.; Dahlman, Ingrid; Kolehmainen, Marjukka; Paananen, Jussi; Rundblad, Amanda; Carlberg, Carsten; Olstad, Ole Kristoffer; Pihlajamaki, Jussi; Holven, Kirsten Bjørklund; Hermansen, Kjeld; Dragsted, Lars O.; Gunnarsdottir, Ingibjörg; Cloetens, Lieselotte; Storm, Matilda Ulmius; Åkesson, Björn; Rosqvist, Fredrik; Hukkanen, Janne; Herzig, Karl-Heinz; Risérus, Ulf; Thorsdottir, Inga; Poutanen, Kaisa S.; Savolainen, Markku J.; Schwab, Ursula; Arner, Peter; Uusitupa, Matti; Ulven, Stine Marie (Molecular Nutrition and Food Research;Volume 63, Issue 13, July 2019, Journal article; Peer reviewed, 2019-04-18)Scope. To explore the effect of a healthy Nordic diet on the global transcriptome profile in peripheral blood mononuclear cells (PBMCs) of subjects with metabolic syndrome. Methods and results. Subjects with metabolic ... -
High-quality fish oil has a more favourable effect than oxidised fish oil on intermediate-density lipoprotein and LDL subclasses: a randomised controlled trial
Rundblad, Amanda; Holven, Kirsten Bjørklund; Ottestad, Inger; Myhrstad, Mari; Ulven, Stine Marie (Journal article; Peer reviewed, 2017)Fish oil (FO) supplementation reduces the risk of CVD. However, it is not known if FO of different qualities have different effects on lipoprotein subclasses in humans. We aimed at investigating the effects of oxidised FO ... -
Increased protein intake affects pro-opiomelanocortin (POMC) processing, immune function and IGF signaling in peripheral blood mononuclear cells of home-dwelling old subjects using a genome-wide gene expression approach
Ulven, Stine Marie; Holven, Kirsten Bjørklund; Rundblad, Amanda; Flatberg, Arnar; Myhrstad, Mari; Karlsen, Karina; Mutt, Shivaprakash; Herzig, Karl-Heinz; Ottestad, Inger; Gjevestad, Gyrd Omholt (Genes and Nutrition;14, Article number: 32 (2019), Journal article; Peer reviewed, 2019-11-28)Background: Adequate protein intake among older adults is associated with better health outcomes such as immune function and metabolic regulation of skeletal muscle, but conflicting results make it difficult to define the ... -
An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome—A SYSDIET Sub-Study
Ulven, Stine Marie; Holven, Kirsten Bjørklund; Rundblad, Amanda; Myhrstad, Mari; Leder, Lena; Dahlman, Ingrid; De Mello, Vanessa D.; Schwab, Ursula; Carlberg, Carsten; Pihlajamaki, Jussi; Hermansen, Kjeld; Dragested, Lars; Gunnarsdottir, Ingibjørg; Cloetens, Lieselotte; Åkesson, Bjørn; Rosqvist, Fredrik; Hukkanen, Janne; Herzig, Karl-Heinz; Savolainen, Markku J.; Risérus, Ulf; Thorsdottir, Inga; Poutanen, Kaisa S.; Arner, Peter; Uusitupa, Matti; Kolehmainen, Marjukka (Nutrients;Volume 11, Issue 12, Journal article; Peer reviewed, 2019-12-03)A healthy dietary pattern is associated with a lower risk of metabolic syndrome (MetS) and reduced inflammation. To explore this at the molecular level, we investigated the effect of a Nordic diet (ND) on changes in the ... -
Replacing saturated fat with polyunsaturated fat modulates peripheral blood mononuclear cell gene expression and pathways related to cardiovascular disease risk using a whole transcriptome approach
Larsen, Sunniva Veen; Holven, Kirsten B.; Christensen, Jacob J.; Flatberg, Arnar; Rundblad, Amanda; Leder, Lena; Blomhoff, Rune; Telle-Hansen, Vibeke; Kolehmainen, Marjukka; Carlberg, Carsten; Myhrstad, Mari C.; Thoresen, Magne; Ulven, Stine M. (Peer reviewed; Journal article, 2021)Scope The aim of this study is to explore the molecular mechanisms underlying the effect of replacing dietary saturated fat (SFA) with polyunsaturated fat (PUFA) on cardiovascular disease (CVD) risk using a whole transcriptome ...