Browsing ODA Open Digital Archive by Author "Holven, Kirsten Bjørklund"
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Beneficial effect on serum cholesterol levels, but not glycaemic regulation, after replacing SFA with PUFA for three days: a randomised crossover trial
Gaundal, Line; Myhrstad, Mari; Leder, Lena; Byfuglien, Marte Gjeitung; Gjøvaag, Terje; Rud, Ida; Retterstøl, Kjetil; Holven, Kirsten Bjørklund; Ulven, Stine Marie; Telle-Hansen, Vibeke (British Journal of Nutrition;, Journal article; Peer reviewed, 2020-09-02)Replacing intake of SFA with PUFA reduces serum cholesterol levels and CVD risk. The effect on glycaemic regulation is, however, less clear. The main objective of the present study was to investigate the short-term effect ... -
Comparison of bioavailability of krill oil versus fish oil and health effect
Ulven, Stine Marie; Holven, Kirsten Bjørklund (Journal article; Peer reviewed, 2015)Background: The aim of this review is to summarize the effects of krill oil (KO) or fish oil (FO) on eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) incorporation in plasma phospholipids or membrane of red blood ... -
Comparison of methods to identify individuals with obesity at increased risk of functional impairment among a population of home-dwelling older adults
Nordengen, Anne Lene; Øyri, Linn Kristin Lie; Ulven, Stine Marie; Raastad, Truls; Holven, Kirsten Bjørklund; Ottestad, Inger Olaug (British Journal of Nutrition;, Peer reviewed; Journal article, 2021-11-09)Obesity is associated with increased muscle mass and muscle strength. Methods taking into account the total body mass to reveal obese older individuals at increased risk of functional impairment are needed. Therefore, we ... -
A comprehensive metabolic profiling of the metabolically healthy obesity phenotype
Telle-Hansen, Vibeke; Christensen, Jacob J.; Formo, Gulla; Holven, Kirsten Bjørklund; Ulven, Stine Marie (Lipids in Health and Disease;19, Article number: 90 (2020), Journal article; Peer reviewed, 2020-05-09)Background: The ever-increasing prevalence of obesity constitutes a major health problem worldwide. A subgroup of obese individuals has been described as “metabolically healthy obese” (MHO). In contrast to metabolically ... -
Dietary fat quality, plasma atherogenic lipoproteins, and atherosclerotic cardiovascular disease: An overview of the rationale for dietary recommendations for fat intake
Christensen, Jacob J.; Arnesen, Erik Kristoffer; Rundblad, Amanda; Telle-Hansen, Vibeke; Narverud, Ingunn; Blomhoff, Rune; Bogsrud, Martin Prøven; Retterstøl, Kjetil; Ulven, Stine Marie; Holven, Kirsten Bjørklund (Peer reviewed; Journal article, 2023)The scientific evidence supporting the current dietary recommendations for fat quality keeps accumulating; however, a paradoxical distrust has taken root among many researchers, clinicians, and in parts of the general public. ... -
Differences in peripheral blood mononuclear cell gene expression and triglyceride composition in lipoprotein subclasses in plasma triglyceride responders and non-responders to omega-3 supplementation
Rundblad, Amanda; Larsen, Sunniva; Myhrstad, Mari; Ottestad, Inger; Thoresen, Magne; Holven, Kirsten Bjørklund; Ulven, Stine Marie (Genes and Nutrition;14, Article number: 10 (2019), Journal article; Peer reviewed, 2019-03-20)Background:Intake of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)reduces fasting triglyceride (TG) levels and may thereby lower cardiovascular disease risk. However, there are ... -
Differential effects of bariatric surgery and lifestyle interventions on plasma levels of Lp(a) and fatty acids
Berk, Kirsten A.; Borgeraas, Heidi; Narverud, Ingunn; Mulder, Monique T.; Øyri, Linn Kristin Lie; Verhoeven, Adrie J M; Småstuen, Milada Cvancarova; Bogsrud, Martin Prøven; Omland, Torbjørn; Hertel, Jens Kristoffer; Gjevestad, Espen Svendsen; Nordstrand, Njord; Holven, Kirsten Bjørklund; Hjelmesæth, Jøran Sture (Peer reviewed; Journal article, 2022)Background: Limited evidence suggests that surgical and non-surgical obesity treatment diferentially infuence plasma Lipoprotein (a) [Lp(a)] levels. Further, a novel association between plasma arachidonic acid and Lp(a) ... -
Does dietary fat affect inflammatory markers in overweight and obese individuals? - a review of randomized controlled trials from 2010 to 2016
Telle-Hansen, Vibeke; Christensen, Jacob J.; Ulven, Stine Marie; Holven, Kirsten Bjørklund (Journal article; Peer reviewed, 2017)Background: Obesity, a major cause of death and disability, is increasing worldwide. Obesity is characterized by a chronic, low-grade inflammatory state which is suggested to play a critical role in the development of ... -
Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: A SYSDIET sub-study
Leder, Lena; Kolehmainen, Marjukka; Narverud, Ingunn; Dahlman, Ingrid; Myhrstad, Mari; De Mello, Vanessa D.; Paananen, Jussi; Carlberg, Carsten; Schwab, Ursula; Herzig, Karl-Heinz; Cloetens, Lieselotte; Storm, Matilda Ulmius; Hukkanen, Janne; Savolainen, Markku J.; Rosqvist, Fredrik; Hermansen, Kjeld; Dragsted, Lars O.; Gunnarsdóttir, Ingibjörg; Thórsdóttir, Inga; Risérus, Ulf; Åkesson, Björn; Thoresen, Magne; Arner, Peter; Poutanen, Kaisa S.; Uusitupa, Matti; Holven, Kirsten Bjørklund; Ulven, Stine Marie (Journal article; Peer reviewed, 2016)Background: Diet has a great impact on the risk of developing features of metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), and cardiovascular diseases (CVD). We evaluated whether a long-term healthy Nordic ... -
Effects of Exercise on Gene Expression of Inflammatory Markers in Human Peripheral Blood Cells: A Systematic Review
Gjevestad, Gyrd Omholt; Holven, Kirsten Bjørklund; Ulven, Stine Marie (Journal article; Peer reviewed, 2015)Regular physical activity seems to be one of the most important contributors to prevent disease and promote health. Being physically active reduces the risk of developing chronic diseases such as cardiovascular disease, ... -
Effects of fish and krill oil on gene expression in peripheral blood mononuclear cells and circulating markers of inflammation: a randomised controlled trial
Rundblad, Amanda; Holven, Kirsten Bjørklund; Bruheim, Inge; Myhrstad, Mari; Ulven, Stine Marie (Journal of Nutritional Science;Volume 7, 2018, Journal article; Peer reviewed, 2018-03-21)Marine n-3 (omega-3) fatty acids alter gene expression by regulating the activity of transcription factors. Krill oil is a source of marine n-3 fattyacids that has been shown to modulate gene expression in animal studies; ... -
Effects of krill oil and lean and fatty fish on cardiovascular risk markers: a randomised controlled trial
Rundblad, Amanda; Holven, Kirsten Bjørklund; Bruheim, Inge; Myhrstad, Mari; Ulven, Stine Marie (Journal article; Peer reviewed, 2018)Fish consumption and supplementation with n-3 fatty acids reduce CVD risk. Krill oil is an alternative source of marine n-3 fatty acids and few studies have investigated its health effects. Thus, we compared krill oil ... -
Exchanging a few commercial, regularly consumed food items with improved fat quality reduces total cholesterol and LDL-cholesterol: A double-blind, randomised controlled trial
Ulven, Stine Marie; Leder, Lena; Elind, Elisabeth; Ottestad, Inger; Christensen, Jacob J.; Telle-Hansen, Vibeke; Skjetne, Anne Juul; Raael, Ellen; Sheikh, Navida Akhter; Holck, Marianne; Torvik, Kristin; Lamglait, Amandine; Thyholt, Kari; Byfuglien, Marte Gjeitung; Granlund, Linda; Andersen, Lene Frost; Holven, Kirsten Bjørklund (Journal article; Peer reviewed, 2016)The healthy Nordic diet has been previously shown to have health bene fi cial effects among subjects at risk of CVD. However, the extent of food changes needed to achieve these effects is less explored. The aim of the ... -
Fatty acid profile and estimated desaturase activities in whole blood are associated with metabolic health
Svendsen, Karianne; Olsen, Thomas; Rusvik, Tove C. N.; Ulven, Stine Marie; Holven, Kirsten Bjørklund; Retterstøl, Kjetil; Telle-Hansen, Vibeke (Lipids in Health and Disease;19, Article number: 102 (2020), Journal article; Peer reviewed, 2020-05-21)Background: The aim was to investigate if fatty acid profile and estimated desaturase activities; stearoyl CoAdesaturase (SCD), delta-5-desaturase and delta-6-desaturase (D5D; D6D), differ between individuals with metabolically ... -
Fish oil supplementation induces Expression of genes related to cell cycle, endoplasmic reticulum stress and apoptosis in peripheral blood mononuclear cells: a transcriptomic approach
Myhrstad, Mari; Ulven, Stine Marie; Günther, Clara-Cecilie; Ottestad, Inger; Holden, Marit; Ryeng, Einar; Borge, Grethe Iren Andersen; Kohler, Achim; Brønner, Kirsti Wettre; Thoresen, Magne; Holven, Kirsten Bjørklund (Journal of International Medicine;276(5), Journal article; Peer reviewed, 2014)Background. Fish oil supplementation has been shown to alter gene expression of mononuclear cells both in vitro and in vivo. However, little is known about the total transcriptome profile in healthy subjects after intake ... -
Gender differences in nutrition literacy levels among university students and employees: a descriptive study.
Svendsen, Karianne; Torheim, Liv Elin; Fjelberg, Vibeke; Sorprud, Anja; Narverud, Ingunn; Retterstøl, Kjetil; Bogsrud, Martin Prøven; Holven, Kirsten Bjørklund; Myhrstad, Mari; Telle-Hansen, Vibeke (Journal of Nutritional Science (JNS);Volume 10, Peer reviewed; Journal article, 2021-07-30)The impact of nutrition information on public health is partly determined by the population’s level of nutrition literacy (NL), which involves functional NL (such as knowledge of dietary guidelines) and critical NL (such ... -
Glycated proteins, glycine, acetate, and monounsaturated fatty acids may act as new biomarkers to predict the progression of type 2 diabetes: Secondary analyses of a randomized controlled trial
Canet, Francisco; Christensen, Jacob J.; Victor, Victor M.; Hustad, Kristin Solheim; Ottestad, Inger; Rundblad, Amanda; Sæther, Thomas; Dalen, Knut Tomas; Ulven, Stine Marie; Holven, Kirsten Bjørklund; Telle-Hansen, Vibeke (Nutrients;Volume 14 / Issue 23, Peer reviewed; Journal article, 2022-12-05)Food protein or food-derived peptides may regulate blood glucose levels; however, studies have shown inconsistent results. The aim of the present study was to characterize subgroups of individuals with increased risk of ... -
Gut microbiota, physical activity and/or metabolic markers in healthy individuals - towards new biomarkers of health
Myhrstad, Mari Charlotte Wik; Ruud, Emilia; Gaundal, Line; Gjøvaag, Terje; Rud, Ida; Retterstøl, Kjetil; Ulven, Stine Marie; Holven, Kirsten Bjørklund; Koehler, Karsten; Telle-Hansen, Vibeke (Peer reviewed; Journal article, 2024)Background: The global prevalence of the metabolic disease Type 2 Diabetes (T2D) is increasing. Risk factors contributing to the development of T2D include overweight and obesity, lack of physical activity (PA), and an ... -
Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with Metabolic Syndrome - A SYSDIET Sub-Study
Myhrstad, Mari; De Mello, Vanessa D.; Dahlman, Ingrid; Kolehmainen, Marjukka; Paananen, Jussi; Rundblad, Amanda; Carlberg, Carsten; Olstad, Ole Kristoffer; Pihlajamaki, Jussi; Holven, Kirsten Bjørklund; Hermansen, Kjeld; Dragsted, Lars O.; Gunnarsdottir, Ingibjörg; Cloetens, Lieselotte; Storm, Matilda Ulmius; Åkesson, Björn; Rosqvist, Fredrik; Hukkanen, Janne; Herzig, Karl-Heinz; Risérus, Ulf; Thorsdottir, Inga; Poutanen, Kaisa S.; Savolainen, Markku J.; Schwab, Ursula; Arner, Peter; Uusitupa, Matti; Ulven, Stine Marie (Molecular Nutrition and Food Research;Volume 63, Issue 13, July 2019, Journal article; Peer reviewed, 2019-04-18)Scope. To explore the effect of a healthy Nordic diet on the global transcriptome profile in peripheral blood mononuclear cells (PBMCs) of subjects with metabolic syndrome. Methods and results. Subjects with metabolic ... -
Helserelatert livskvalitet og ernæringsstatus blant eldre hjemmeboende over 70 år
Henriksen, Christine; Golberg, Silje B; Ulven, Stine Marie; Holven, Kirsten Bjørklund; Ottestad, Inger (Norsk Tidsskrift for Ernæring;Nr.2/2018, Journal article; Peer reviewed, 2018-06-28)Bakgrunn: Det er vanlig å inkludere helserelatert livskvalitet i kliniske studier, men det er få som har undersøkt dette hos eldre hjemme boende ≥ 70 år. Hensikten med denne studien var primært å beskrive helserelatert ...