Blar i ODA Open Digital Archive på forfatter "Holven, Kirsten Bjørklund"
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High-quality fish oil has a more favourable effect than oxidised fish oil on intermediate-density lipoprotein and LDL subclasses: a randomised controlled trial
Rundblad, Amanda; Holven, Kirsten Bjørklund; Ottestad, Inger; Myhrstad, Mari; Ulven, Stine Marie (Journal article; Peer reviewed, 2017)Fish oil (FO) supplementation reduces the risk of CVD. However, it is not known if FO of different qualities have different effects on lipoprotein subclasses in humans. We aimed at investigating the effects of oxidised FO ... -
Impact of a healthy dietary pattern on gut microbiota and systemic inflammation in humans
Telle-Hansen, Vibeke; Holven, Kirsten Bjørklund; Ulven, Stine Marie (Nutrients;Volume 10, Issue 11, Journal article; Journal article; Peer reviewed, 2018-11-16)Gut microbiota have recently been suggested to play a part in low-grade systemic inflammation, which is considered a key risk factor for cardiometabolic disorders. Diet is known to affect gut microbiota; however, the ... -
Increased protein intake affects pro-opiomelanocortin (POMC) processing, immune function and IGF signaling in peripheral blood mononuclear cells of home-dwelling old subjects using a genome-wide gene expression approach
Ulven, Stine Marie; Holven, Kirsten Bjørklund; Rundblad, Amanda; Flatberg, Arnar; Myhrstad, Mari; Karlsen, Karina; Mutt, Shivaprakash; Herzig, Karl-Heinz; Ottestad, Inger; Gjevestad, Gyrd Omholt (Genes and Nutrition;14, Article number: 32 (2019), Journal article; Peer reviewed, 2019-11-28)Background: Adequate protein intake among older adults is associated with better health outcomes such as immune function and metabolic regulation of skeletal muscle, but conflicting results make it difficult to define the ... -
An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome—A SYSDIET Sub-Study
Ulven, Stine Marie; Holven, Kirsten Bjørklund; Rundblad, Amanda; Myhrstad, Mari; Leder, Lena; Dahlman, Ingrid; De Mello, Vanessa D.; Schwab, Ursula; Carlberg, Carsten; Pihlajamaki, Jussi; Hermansen, Kjeld; Dragested, Lars; Gunnarsdottir, Ingibjørg; Cloetens, Lieselotte; Åkesson, Bjørn; Rosqvist, Fredrik; Hukkanen, Janne; Herzig, Karl-Heinz; Savolainen, Markku J.; Risérus, Ulf; Thorsdottir, Inga; Poutanen, Kaisa S.; Arner, Peter; Uusitupa, Matti; Kolehmainen, Marjukka (Nutrients;Volume 11, Issue 12, Journal article; Peer reviewed, 2019-12-03)A healthy dietary pattern is associated with a lower risk of metabolic syndrome (MetS) and reduced inflammation. To explore this at the molecular level, we investigated the effect of a Nordic diet (ND) on changes in the ... -
Oxidised fish oil does not influence established markers of oxidative stress in healthy human subjects: a randomised controlled trial
Ottestad, Inger; Vogt, Kjell Gjermund; Retterstøl, Kjetil; Myhrstad, Mari; Haugen, John-Erik; Nilsson, Astrid; Ravn-Haren, Gitte; Nordvi, Berit; Brønner, Kirsti Wettre; Andersen, Lene Frost; Holven, Kirsten Bjørklund; Ulven, Stine Marie (British Journal of Nutrition;, Journal article; Peer reviewed, 2011)Intake of fish oil reduces the risk of CHD and CHD deaths. Marine n-3 fatty acids (FA) are susceptible to oxidation, but to our knowledge, the health effects of intake of oxidised fish oil have not previously been ... -
Plasma fatty acid levels and gene expression related to lipid metabolism in peripheral blood mononuclear cells: A cross-sectional study in healthy subjects
Larsen, Sunniva Veen; Holven, Kirsten Bjørklund; Ottestad, Inger; Dagsland, Kine Margrethe; Myhrstad, Mari; Ulven, Stine Marie (Genes & Nutrition;2018 13:9, Journal article; Peer reviewed, 2018-04-10)Background: Solid evidence indicates that intake of marine n-3 fatty acids lower serum triglycerides, and that replacing saturated fatty acids (SFA) with polyunsaturated fatty acids (PUFA) reduces plasma total cholesterol ... -
Real-world impact of transitioning from one lipoprotein(a) assay to another in a clinical setting
Jeevanathan, Janeni; Blom, Sigrid Marie; Olsen, Thomas; Holven, Kirsten Bjørklund; Arnesen, Erik Kristoffer; Trydal, Torleif; Nordestgaard, Børge G; Sovershaev, Michael; Chen, Ying; Retterstøl, Kjetil; Christensen, Jacob Juel (Peer reviewed; Journal article, 2024)Background and aims: Different lipoprotein(a) [Lp(a)] assays may affect risk stratification of individuals and thus clinical decision-making. We aimed to investigate how transitioning between Lp(a) assays at a large central ... -
Reduced plasma concentration of branched-chain amino acids in sarcopenic older subjects: a cross-sectional study
Ottestad, Inger; Ulven, Stine Marie; Øyri, Linn Kristin Lie; Sandvei, Kristin Søfteland; Gjevestad, Gyrd Omholt; Bye, Asta; Sheikh, Navida Akhter; Biong, Anne Sofie; Andersen, Lene Frost; Holven, Kirsten Bjørklund (British Journal of Nutrition;Volume 120, Issue 4, Journal article; Peer reviewed, 2018-06-18)Branched chain amino acids (BCAAs) are essential amino acids necessary for muscle mass maintenance. Little is known about the plasma concentrations of BCAAs and the protein intake in relation to sarcopenia. We aimed ... -
Replacing saturated fatty acids with polyunsaturated fatty acids increases the abundance of Lachnospiraceae and is associated with reduced total cholesterol levels-a randomized controlled trial in healthy individuals
Telle-Hansen, Vibeke; Gaundal, Line; Bastani, Nasser Ezzatkhah; Rud, Ida; Byfuglien, Marte G.; Gjøvaag, Terje; Retterstøl, Kjetil; Holven, Kirsten Bjørklund; Ulven, Stine Marie; Myhrstad, Mari (Peer reviewed; Journal article, 2022)Improving dietary fat quality strongly affects serum cholesterol levels and hence the risk of cardiovascular diseases (CVDs). Recent studies have identified dietary fat as a potential modulator of the gut microbiota, a ... -
The PBMC transcriptome profile after intakeof oxidized versus high-quality fish oil: anexplorative study in healthy subjects
Myhrstad, Mari; Ottestad, Inger; Günther, Clara-Cecilie; Ryeng, Einar; Holden, Marit; Nilsson, Astrid; Brønner, Kirsti Wettre; Kohler, Achim; Borge, Grethe Iren Andersen; Holven, Kirsten Bjørklund; Ulven, Stine Marie (Peer reviewed; Journal article, 2016-05-31)Background: Marine long-chain polyunsaturated fatty acids are susceptible to oxidation, generating a range of different oxidation products with suggested negative health effects. The aim of the present study was to ...