AHUS - Medisinsk divisjon
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Plasma marine n-3 polyunsaturated fatty acids and cardiovascular risk factors: data from the ACE 1950 study
(Springer, 2019-05-23)Abstract Purpose A high intake of marine n-3 polyunsaturated fatty acids (PUFAs) might improve cardiovascular (CV) health. We conducted a cross-sectional study to investigate associations between plasma phospholipid ... -
Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study
(Elsevier, 2019-10)Abstract Background and aims Several risk prediction models for coronary heart disease (CHD) are available today, however, they only explain a modest proportion of the incidence. Circulating microRNAs (miRs) have ... -
NAD+ in aging: molecular mechanisms and translational implications
(Elsevier, 2017-10)AB The coenzyme NAD+ is critical in cellular bioenergetics and adaptive stress responses. Its depletion has emerged as a fundamental feature of aging that may predispose to a wide range of chronic diseases. Maintenance of ... -
B-cell composition in the blood and cerebrospinal fluid of multiple sclerosis patients treated with dimethyl fumarate
(Elsevier, 2018-08-30)Background:B cells may contribute to the immunopathogenesis of multiple sclerosis (MS). Dimethyl fumarate(DMF) has recently been shown to reduce the frequency of memory B cells in blood, but it is not known whetherthe drug ... -
Left ventricular biomechanics in professional football players
(Wiley, 2017-04-04)Chronic exercise induces adaptive changes of left ventricular (LV) ejection and filling capacities which may be detected by novel speckle‐tracking echocardiography (STE) and tissue Doppler imaging (TDI)‐based techniques. ... -
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
(Elsevier, 2017-02-02)Background & Aims Prognostic biomarkers are lacking in primary sclerosing cholangitis, hampering patient care and the development of therapy. We aimed to identify novel protein biomarkers of disease severity and prognosis ... -
Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin: Educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB)
(De Gruyter, 2018-06-10)Two interferences recently brought to the forefront as patient safety issues include hemolysis (hemoglobin) and biotin (vitamin B7). The International Federation for Clinical Chemistry Committee on Cardiac Biomarkers ... -
Novel biomarkers of cardiovascular disease: Applications in clinical practice
(Taylor & Francis, 2018-11-20)Measurement of biomarkers has revolutionized the work-up of patients with suspected cardiovascular disease. The most widely used contemporary cardiovascular biomarkers are the natriuretic peptides in the diagnosis and ... -
Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells
(Frontiers Media, 2018-11-20)Background: Aortic valve calcification is an active proliferative process, where interstitial cells of the valve transform into either myofibroblasts or osteoblast-like cells causing valve deformation, thickening of cusps ... -
Health status in subjects with suspected obstructive sleep apnea and comparison with a general population
(Nature, 2018-04-03)The purpose of this study was to assess health status (HS) in patients with clinical suspicion of obstructive sleep apnea (OSA) in order to estimate the dose response relationship between HS and OSA severity, and to ... -
Adherence to subcutaneous interferon beta-1a treatment using an electronic injection device: a prospective open-label scandinavian noninterventional study (The scansmart study)
(Dove Medical Press, 2018-04-19)Background: Disease modifying drugs help control the course of relapsing remitting multiple sclerosis (RRMS); however, good adherence is needed for long-term outcomes. Objective: To evaluate patient adherence to treatment ... -
Patient knowledge on stroke risk factors, symptoms and treatment options
(Dove Medical Press, 2018-02-07)Background: Public campaigns focus primarily on stroke symptom and risk factor knowledge, but patients who correctly recognize stroke symptoms do not necessarily know the reason for urgent hospitalization. The aim of this ... -
Fatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients
(Baishideng Publishing Group, 2018-08-07)AIM To investigate if vitamin D deficiency is associated with fatigue in patients with inflammatory bowel disease (IBD). METHODS IBD patients were recruited from nine hospitals in the southeastern and western regions ... -
Sofosbuvir and velpatasvir for hepatitis C virus infection in people with recent injection drug use (SIMPLIFY): an open-label, single-arm, phase 4, multicentre trial
(Elsevier, 2018-03)Background Despite revised guidelines that no longer exclude people who inject drugs (PWID) from treatment for hepatitis C virus (HCV) infection, many clinicians are reluctant to treat recent PWID. This study aimed to ... -
Tested and reported executive problems in children and youth epilepsy
(Wiley, 2018-04-16)Objectives Executive problems in children and youth with epilepsy influence their ability to handle important aspects of daily life activities. The present study sought to explore factors associated with executive problems ... -
Prevalence of carotid plaque in a 63- to 65-Year-Old Norwegian cohort from the general population: The ACE (Akershus Cardiac Examination) 1950 study
(Wiley, 2018-05-08)Background New data on extracranial carotid atherosclerosis are needed, as improved ultrasound techniques may detect more atherosclerosis, the definition of plaque has changed over the years, and better cardiovascular ... -
Vertebral Bone Mineral Density Measured by Quantitative Computed Tomography With and Without a Calibration Phantom: A Comparison Between 2 Different Software Solutions
(Elsevier, 2018-03-27)Quantitative computed tomography (CT) can be used to quantify bone mineral density (BMD) in the spine from clinical CT scans. We aimed to determine agreement and precision of BMD measurements by 2 different methods: ... -
Bioavailable Testosterone Is Positively Associated With Bone Mineral Density in Male Kidney Transplantation Candidates
(Elsevier, 2018-05)Introduction Low levels of sex hormones are common in patients with chronic kidney disease (CKD) and may be a contributing factor to bone fragility. We investigated associations between levels of sex hormones and bone ... -
Assay of steroids by liquid chromatography-tandem mass spectrometry in monitoring 21-hydroxylase deficiency
(Bio Scientifica, 2018-12)Immunoassays of steroid hormones are still used in the diagnosis and monitoring of patients with congenital adrenal hyperplasia. However, cross-reactivity between steroids can give rise to falsely elevated steroid levels. ... -
Effect of exogenous estrogens and progestogens on the course of migraine during reproductive age: A consensus statement by the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESCRH)
(BMC Springer, 2018-08-31)We systematically reviewed data about the effect of exogenous estrogens and progestogens on the course of migraine during reproductive age. Thereafter a consensus procedure among international experts was undertaken to ...
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