dc.contributor.author | Solbak, Marian S. | |
dc.contributor.author | Henning, Mette Karen | |
dc.contributor.author | England, Andrew | |
dc.contributor.author | Martinsen, Anne Catrine Trægde | |
dc.contributor.author | Aaløkken, Trond M | |
dc.contributor.author | Johansen, Safora | |
dc.date.accessioned | 2021-02-04T13:07:22Z | |
dc.date.accessioned | 2021-02-05T13:21:30Z | |
dc.date.available | 2021-02-04T13:07:22Z | |
dc.date.available | 2021-02-05T13:21:30Z | |
dc.date.issued | 2020-09-11 | |
dc.identifier.citation | Solbak, Henning, England, Martinsen, Aaløkken, Johansen. Impact of iodine concentration and scan parameters on image quality, contrast enhancement and radiation dose in thoracic CT. European Radiology Experimental. 2020;4:57:1-8 | en |
dc.identifier.issn | 2509-9280 | |
dc.identifier.uri | https://hdl.handle.net/10642/9480 | |
dc.description.abstract | Background: We investigated the impact of varying contrast medium (CM) densities and x-ray tube potentials on contrast enhancement (CE), image quality and radiation dose in thoracic computed tomography (CT) using two different scanning techniques. Methods: Seven plastic tubes containing seven different CM densities ranging from of 0 to 600 HU were positioned inside a commercial chest phantom with padding, representing three different patient sizes. Helical scans of the phantom in single-source mode were obtained with varying tube potentials from 70 to 140 kVp. A constant volume CT dose index (CTDIvol) depending on phantom size and automatic dose modulation was tested. CE (HU) and image quality (contrast-to-noise ratio, CNR) were measured for all combinations of CM density and tube potential. A reference threshold of CE and kVp was defined as ≥ 200 HU and 120 kVp. Results: For the medium-sized phantom, with a specific CE of 100–600 HU, the diagnostic CE (200 HU) at 70 kVp was ~ 90% higher than at 120 kVp, for both scan techniques (p < 0.001). Changes in CM density/specific HU together with lower kVp resulted in significantly higher CE and CNR (p < 0.001). When changing only the kVp, no statistically significant differences were observed in CE or CNR (p ≥ 0.094), using both dose modulation and constant CTDIvol. Conclusions: For thoracic CT, diagnostic CE (≥ 200 HU) and maintained CNR were achieved by using lower CM density in combination with lower tube potential (< 120 kVp), independently of phantom size. | en |
dc.language.iso | en | en |
dc.publisher | Springer | en |
dc.relation.ispartofseries | European Radiology Experimental;4, Article number: 57 (2020) | |
dc.rights | Creative Commons Attribution 4.0 International (CC BY 4.0) License | en |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Contrast media | en |
dc.subject | Phantoms | en |
dc.subject | Radiation dosages | en |
dc.subject | Thorax | en |
dc.subject | Tomography | en |
dc.subject | Imaging | en |
dc.subject | Computed x-rays | en |
dc.title | Impact of iodine concentration and scan parameters on image quality, contrast enhancement and radiation dose in thoracic CT | en |
dc.type | Journal article | |
dc.type | Peer reviewed | en |
dc.date.updated | 2021-02-04T13:07:22Z | |
dc.description.version | publishedVersion | en |
dc.identifier.doi | https://doi.org/10.1186/s41747-020-00184-z | |
dc.identifier.cristin | 1840336 | |
dc.source.journal | European Radiology Experimental | |