Duration of Lactation and Maternal Risk of MetabolicSyndrome: A Systematic Review and Meta-Analysis
Journal article, Peer reviewed
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OriginalversjonTørris C, Bjørnnes AK. Duration of Lactation and Maternal Risk of MetabolicSyndrome: A Systematic Review and Meta-Analysis. Nutrients. 2020 https://dx.doi.org/10.3390/nu12092718
Cardiovascular disease (CVD) is the leading cause of death of women across all ages, and targeting modiﬁable risk factors, such as those comprised in metabolic syndrome (MetS) (e.g., waist circumference, lipid proﬁle, blood pressure, and blood glucose), is of great importance. An inverse association between lactation and CVD has been suggested, and lactation may decrease the risk of MetS. This systematic review and meta-analysis examined how lactation may aﬀect the development and prevalence of MetS in women. A literature search was performed using Cinahl, Embase, Web of Science, and PubMed. A total of 1286 citations were identiﬁed, and ﬁnally, ten studies (two prospective and eight cross-sectional) were included. Seven studies (two prospective and ﬁve cross-sectional) revealed Associations between lactation and MetS, suggesting that breastfeeding might prevent or improve metabolic health and have a protective role in MetS prevention. This protective role might be related to the duration of lactation; however, a lack of controlling for potential confounders, such as parity, might inﬂict the results. The pooled eﬀect was non-conclusive. Additional research is required to further explore the duration of lactation and its potential role in improving or reversing MetS and its components.