An international investigation into O red blood cell unit administration in hospitals: the GRoup O Utilization Patterns (GROUP) study
Zeller, Michelle P.; Barty, Rebecca; Aandahl, Astrid; Apelseth, Torunn Oveland; Callum, Jeannie; Dunbar, Nancy M.; Elahie, Allahna; Garritsen, Henk; Hancock, Helen; Kutner, José Mauro; Manukian, Belinda; Mizuta, Shuichi; Okuda, Makoto; Pagano, Monica B.; Pogłód, Ryszard; Rushford, Kylie; Selleng, Kathleen; Sørensen, Claess Henning; Sprogøe, Ulrik; Staves, Julie; Weiland, Thorsten; Wendel, Silvano; Wood, Erica M.; Watering, Leo van de; Wordragen-Vlaswinkel, Maria van; Ziman, Alyssa; Zwaginga, Jaap Jan; Murphy, Michael F.; Heddle, Nancy M.; Yazer, Mark H.
Journal article, Peer reviewed
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Original versionZeller, M. P., Barty, R., Aandahl, A., Apelseth, T. O., Callum, J., Dunbar, N. M., . . . Biomedical Excellence for Safer Transfusion, C. (2017). An international investigation into O red blood cell unit administration in hospitals: the GRoup O Utilization Patterns (GROUP) study. Transfusion, 57(10), 2329-2337. doi:10.1111/trf.14255 http://dx.doi.org/10.1111/trf.14255
BACKGROUND: Transfusion of group O blood to non-O recipients, or transfusion of D- blood to D+ recipients, can result in shortages of group O or D- blood, respectively. This study investigated RBC utilization patterns at hospitals around the world and explored the context and policies that guide ABO blood group and D type selection practices. STUDY DESIGN AND METHODS: This was a retrospective study on transfusion data from the 2013 calendar year. This study included a survey component that asked about hospital RBC selection and transfusion practices and a data collection component where participants submitted information on RBC unit disposition including blood group and D type of unit and recipient. Units administered to recipients of unknown ABO or D group were excluded. RESULTS: Thirty-eight hospitals in 11 countries responded to the survey, 30 of which provided specific RBC unit disposition data. Overall, 11.1% (21,235/191,397) of group O units were transfused to non-O recipients; 22.6% (8777/38,911) of group O D- RBC units were transfused to O D+ recipients, and 43.2% (16,800/38,911) of group O D- RBC units were transfused to recipients that were not group O D-. Disposition of units and hospital transfusion policy varied within and across hospitals of different sizes, with transfusion of group O D- units to non-group O D- patients ranging from 0% to 33%. CONCLUSION: A significant proportion of group O and D- RBC units were transfused to compatible, nonidentical recipients, although the frequency of this practice varied across sites.