• CD8 + T cell gene expression analysis identifies differentially expressed genes between multiple sclerosis patients and healthy controls 

      Brorson, Ina Skaara; Eriksson, Anna Maria; Leikfoss, Ingvild Sørum; Vitelli, Valeria; Celius, Elisabeth Gulowsen; Luders, Torben; Berge, Tone; Harbo, Hanne Flinstad; Nilsen, Hilde; Bos-Haugen, Steffan Daniël (Multiple Sclerosis Journal, Experimental, Translational and Clinical;Volume: 6, issue: 4, Journal article; Peer reviewed, 2020-12-09)
      Background: Genetic and clinical observations have indicated T cells are involved in MS pathology. There is little insight in how T cells are involved and whether or not these can be used as markers for MS. Objectives: ...
    • Increased DNA methylation of SLFN12 in CD4+ and CD8+ T cells from multiple sclerosis patients 

      Rhead, Brooke; Brorson, Ina Skaara; Berge, Tone; Adams, Cameron; Quach, Hong; Moen, Stine Marit; Berg-Hansen, Pål; Celius, Elisabeth Gulowsen; Sangurdekar, Dipen; Bronson, Paola G.; Lea, Rodney A.; Burnard, Sean; Maltby, Vicky E.; Scott, Rodney J; Lechner-Scott, Jeannette; Harbo, Hanne Flinstad; Bos, Steffan Daniel; Barcellos, Lisa F (PLoS ONE;13 (10): e0206511, Journal article; Journal article; Peer reviewed, 2018-10-31)
      DNA methylation is an epigenetic mark that is influenced by environmental factors and is associated with changes to gene expression and phenotypes. It may link environmental exposures to disease etiology or indicate important ...
    • No differential gene expression for CD4+ T cells of MS patients and healthy controls. 

      Brorson, Ina Skaara; Eriksson, Anna; Leikfoss, Ingvild Sørum; Celius, Elisabeth Gulowsen; Berg-Hansen, Pål; Barcellos, Lisa F.; Berge, Tone; Harbo, Hanne Flinstad; Bos, Steffan Daniel (Multiple Sclerosis Journal - Experimental, Translational and Clinical;Volume 5(2), Journal article; Peer reviewed, 2019-05-20)
      Background: Multiple sclerosis-associated genetic variants indicate that the adaptive immune system plays an important role in the risk of developing multiple sclerosis. It is currently not well understood how these multiple ...