Blar i HV - Institutt for naturvitenskapelige helsefag på emneord "Antiepileptic drugs"

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    • Antiepileptic and antidepressive polypharmacy in patients with multiple sclerosis. 

      Beiske, Georg; Holmøy, Trygve; Beiske, Antonie Giæver; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Multiple sclerosis international;2015, Journal article; Peer reviewed, 2015)
      Objective. Patients with multiple sclerosis (MS) are often suffering from neuropathic pain. Antiepileptic drugs (AEDs) and tricyclic antidepressants (TCAs) are commonly used and are susceptible to be involved in drug ...

    • Changes in the use of antiseizure medications in children and adolescents in Norway, 2009–2018 

      Heger, Katrine; Skipsfjord, Julia; Kiselev, Yury; Burns, Margrete Larsen; Aaberg, Kari Modalsli; Johannessen, Svein Ivar; Skurtveit, Svetlana Ondrasova; Landmark, Cecilie Johannessen (Epilepsy Research;Volume 181, March 2022, 106872, Peer reviewed; Journal article, 2022-02-15)
      Background: The use of antiseizure medications (ASMs) in the pediatric population is poorly studied. The purpose of this study was to investigate changes in the use of ASMs in children and adolescents compared to adults, ...

    • Clinical experience combined with therapeutic drug monitoringof lacosamide 

      Svendsen, Torleiv; Brodtkorb, Eylert; Baftiu, Arton; Lossius, Morten; Nakken, Karl Otto; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Acta Neurologica Scandinavica;Volume 141, Issue 4, Journal article; Peer reviewed, 2019-12-14)
      Objective: Lacosamide (LCM) is an antiepileptic drug (AED) with insufficient clinical experience in patients with intellectual disability (ID). They often have more severe epilepsy with comorbidities. The objective was to ...

    • Effect and tolerability of perampanel in patients with drug-resistant epilepsy 

      Lossius, Ida Marie Bakke; Svendsen, Torleiv; Sødal, Hild Flatmark; Kjeldstadli, Kari Grandaunet; Lossius, Morten Ingvar; Nakken, Karl Otto; Landmark, Cecilie Johannessen (Epilepsy & Behavior;Volume 119, June 2021, 107965, Peer reviewed; Journal article, 2021-04-30)
      Objective: Perampanel is one of the most recently approved antiseizure medications. The aim of the present study was to assess clinical efficacy and tolerability, in combination with pharmacokinetic variability, of perampanel ...

    • Long-term follow-up with therapeutic drug monitoring of antiepileptic drugs in patients with juvenile myoclonic epilepsy 

      Landmark, Cecilie Johannessen; Fløgstad, Ida; Baftiu, Arton; Syvertsen, Marte Roa; Enger, Ulla Helene; Johannessen, Svein Ivar (Epilepsy Research;Volume 155, September 2019, Journal article; Peer reviewed, 2019-05-30)
      Background and purpose: Patients with juvenile myoclonus epilepsy (JME) may experience uncontrolled seizures and challenges regarding adherence. Implementation of therapeutic drug monitoring (TDM) may contribute to ...

    • Pharmacokinetic variability and clinical use of lacosamide in children and adolescents in Denmark and Norway 

      Burns, Margrete Larsen; Nikanorova, Marina; Baftiu, Arton; Rasmussen, Jan Borg; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Therapeutic Drug Monitoring;41 (3): 340–347, JUNE 2019, Journal article; Peer reviewed, 2019-01-01)
      Background: The indication for the antiepileptic drug (AED) lacosamide (LCM) was recently extended to include children from the age of four. Real-life data on the use and serum concentrations of LCM in children and ...

    • Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines 

      Reimers, Arne; Berg, Jon Andsnes; Burns, Margrete Larsen; Brodtkorb, Eylert; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Journal article; Peer reviewed, 2018)
      Background and objective: Laboratories sometimes use different reference ranges for the same antiepileptic drug (AED), particularly for new and poorly investigated drugs. This may contribute to misunderstandings, concerns ...

    • Treatment and challenges with antiepileptic drugs in patients with juvenile myoclonic epilepsy 

      Landmark, Cecilie Johannessen; Fløgstad, Ida; Syvertsen, Marte Roa; Baftiu, Arton; Enger, Ulla Helene; Koht, Jeanette; Johannessen, Svein Ivar (Epilepsy & Behavior;Volume 98, Part A, September 2019, Journal article; Peer reviewed, 2019-07-19)
      Background: Patients with juvenile myoclonic epilepsy (JME) may have uncontrolled seizures. The purpose of this study was to investigate the use and challenges with antiepileptic drugs (AEDs) and the patients' view of ...