Blar i HV - Institutt for naturvitenskapelige helsefag på forfatter "Christiansen, Irene Kraus"

Viser treff 1-6 av 6

    • HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization 

      Meisal, Roger; Rounge, Trine Ballestad; Christiansen, Irene Kraus; Eieland, Alexander Kirkeby; Worren, Merete Molton; Molden, Tor; Kommedal, Øyvind; Hovig, Eivind; Leegaard, Truls Michael; Ambur, Ole Herman (Journal article; Peer reviewed, 2017)
      Sensitive and specific genotyping of human papillomaviruses (HPVs) is important for population-based surveillance of carcinogenic HPV types and for monitoring vaccine effectiveness. Here we compare HPV genotyping by Next ...

    • HPV16 and HPV18 type-specific APOBEC3 and integration profiles in different diagnostic categories of cervical samples 

      Lagström, Sonja; Løvstad, Alexander H; Umu, Sinan Uğur; Ambur, Ole Herman; Nygård, Mari; Rounge, Trine Ballestad; Christiansen, Irene Kraus (Tumour Virus Research;Volume 12, December 2021, 200221, Peer reviewed; Journal article, 2021-07-14)
      Human papillomavirus (HPV) 16 and 18 are the most predominant types in cervical cancer. Only a small fraction of HPV infections progress to cancer, indicating that additional factors and genomic events contribute to the ...

    • HPV16 whole genome minority variants in persistent infections from young Dutch women 

      Lagström, Sonja; van der Weele, Pascal; Rounge, Trine Ballestad; Christiansen, Irene Kraus; King, Audrey; Ambur, Ole Herman (Journal of Clinical Virology;Volume 119, October 2019, Journal article; Peer reviewed, 2019-08-09)
      Background: Chronic infections by one of the oncogenic human papillomaviruses (HPVs) are responsible for near 5% of the global cancer burden and HPV16 is the type most often found in cancers. HPV genomes displayunexpected ...

    • Intra-host sequence variability in human papillomavirus 

      Mandishora, Racheal Shamiso Dube; Gjøtterud, Kristina Stormo; Lagström, Sonja; Stray-Pedersen, Babill; Duri, Kerina; Chin'ombe, Nyasha; Nygård, Mari; Christiansen, Irene Kraus; Ambur, Ole Herman; Chirenje, Mike Zvavahera; Rounge, Trine Ballestad (Papillomavirus Research. The Journal of HPV and other Small DNA Tumor Viruses;Volume 5, June 2018, Journal article; Peer reviewed, 2018-04-30)
      Human papillomaviruses (HPVs) co-evolve slowly with the human host and each HPV genotype displays epithelial tropisms. We assessed the evolution of intra HPV genotype variants within samples, and their association to ...

    • Substantial Decline in Prevalence of Vaccine-Type and Nonvaccine-Type Human Papillomavirus (HPV) in Vaccinated and Unvaccinated Girls 5 Years After Implementing HPV Vaccine in Norway 

      Feiring, Berit; Laake, Ida; Christiansen, Irene Kraus; Hansen, Mona Lindsethmo; Stålcrantz, Jeanette; Ambur, Ole Herman; Magnus, Per; Jonassen, Christine M; Trogstad, Lill (Journal of Infectious Diseases;, Journal article; Peer reviewed, 2018-07-16)
      Background: In 2009, quadrivalent human papillomavirus (HPV) vaccine was introduced in a school-based single-cohort program targeting 12-year-old girls in Norway. We estimated the impact of the Norwegian HPV immunization ...

    • TaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration 

      Lagström, Sonja; Umu, Sinan Uğur; Lepistö, Maija; Ellonen, Pekka; Meisal, Roger; Christiansen, Irene Kraus; Ambur, Ole Herman; Rounge, Trine Ballestad (Scientific Reports;9, Article number: 524 (2019), Journal article; Peer reviewed, 2018-11-26)
      HPV genomic variability and chromosomal integration are important in the HPV-induced carcinogenic process. To uncover these genomic events in an HPV infection, we have developed an innovative and cost-effective sequencing ...