Blar i Sentraladministrasjonen på tidsskrift "BioRxiv"
Viser treff 1-2 av 2
-
Criticality as a measure of developing proteinopathy in engineered human neural networks
(bioRxiv;, Journal article, 2020-05-04)A patterned spread of proteinopathy represents a common characteristic of many neurodegenerative diseases. In Parkinson’s disease (PD), misfolded forms of alpha-synuclein proteins aggregate and accumulate in hallmark ... -
Structural and functional alterations associated with the LRRK2 G2019S mutation revealed in structured human neural networks
(bioRxiv;, Journal article, 2020-05-02)Mutations in the LRRK2 gene have been widely linked to Parkinson ́s disease. The G2019S variant has been shown to contribute uniquely to both familial and sporadic forms of the disease. LRRK2-related mutations have been ...