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dc.contributor.authorTangen, Gro Gujorden_US
dc.contributor.authorEngedal, Knuten_US
dc.contributor.authorBergland, Astriden_US
dc.contributor.authorMoger, Tron Andersen_US
dc.contributor.authorHansson, Oskaren_US
dc.contributor.authorMengshoel, Anne Mariten_US
dc.date.accessioned2016-03-22T09:12:23Z
dc.date.available2016-03-22T09:12:23Z
dc.date.issued2015-02-15en_US
dc.identifier.citationTangen, G. G., Engedal, K., Bergland, A., Moger, T. A., Hansson, O., & Mengshoel, A. M. (2015). Spatial navigation measured by the Floor Maze Test in patients with subjective cognitive impairment, mild cognitive impairment, and mild Alzheimer's disease. Int Psychogeriatr, 1-9.en_US
dc.identifier.issn1041-6102en_US
dc.identifier.otherFRIDAID 1219121en_US
dc.identifier.urihttps://hdl.handle.net/10642/3193
dc.description.abstractBackground : Impaired spatial navigation is an early sign of Alzheime r disease (AD), but this can be difficult to assess in clinical practice. We examined how the performance on the Floor Maze Test (FMT), which combines navigation with walking, differed between patients with subjective cognitive impairment (SCI), mild cogni tive impairment (MCI), and mild AD. We also explored if there was a significant relationship between the FMT and the cognitive tests or sociodemographic factors. Methods: Th e study included 128 patients from a memory clinic classified as having SCI (n = 19 ), MCI (n = 20), and mild AD (n = 89). Spatial navigation was assessed by having the patients walk through the FMT , a two - dimensional maze. Both timed measures and number of errors were recorded. Cognitive function was assessed by the Word List Memory test , the Clock Drawing Test, the Trail Making Test s (TMT) A and B, and the Mini Mental Status Examination (MMSE). Results: The p atients with MCI were slower than those with SCI , while the patients with mild AD more frequently completed the FMT with errors or gave up than the patients with MCI. Performance on the FMT was significantly associated with executive function (measured by TMT‒B). Conclusions: The performances on the F MT worsened with increasing severity of cognitive impairment, and the FMT was primarily associated with executive function. The explained variance was relatively low, which may indicate that the standard cognit ive test battery does not capture impairments of spatial navigation.en_US
dc.language.isoengen_US
dc.publisherCambridge University Pressen_US
dc.subjectspatial navigationen_US
dc.subjectcognitionen_US
dc.subjectAlzheimeren_US
dc.subjectmild cognitive impairmenten_US
dc.subjectsubjective cognitive impairmenten_US
dc.titleSpatial navigation measured by the Floor Maze Test in patients with subjective cognitive impairment, mild cognitive impairment, and mild Alzheimer's diseaseen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.identifier.doihttp://dx.doi.org/10.1017/S1041610215000022


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