|Tangen, Gro Gujord
|Moger, Tron Anders
|Mengshoel, Anne Marit
|Tangen, G. G., Engedal, K., Bergland, A., Moger, T. A., Hansson, O., & Mengshoel, A. M. (2015). Spatial navigation measured by the Floor Maze Test in patients with subjective cognitive impairment, mild cognitive impairment, and mild Alzheimer's disease. Int Psychogeriatr, 1-9.
Impaired spatial navigation is an early sign of Alzheime
r disease (AD), but this
can be difficult to assess in clinical practice. We examined how the performance on the Floor
Maze Test (FMT), which combines navigation with walking, differed between patients with
subjective cognitive impairment (SCI), mild cogni
tive impairment (MCI), and mild AD. We
if there was a
between the FMT and the cognitive tests
or sociodemographic factors.
e study included 128 patients from a memory clinic classified as having SCI
), MCI (n
20), and mild AD (n
Spatial navigation was assessed by
patients walk through
Both timed measures and number of
errors were recorded.
Cognitive function was assessed by
the Word List Memory test
Clock Drawing Test,
Trail Making Test
A and B, and
the Mini Mental Status
atients with MCI
, while the patients with mild
AD more frequently completed the FMT with errors or
gave up than the patients with MCI.
Performance on the FMT was significantly associated with executive function (measured by
The performances on
worsened with increasing severity of cognitive
impairment, and the FMT was primarily associated with executive function. The explained
variance was relatively low, which may indicate that the standard cognit
ive test battery does
not capture impairments of spatial navigation.
|Cambridge University Press
|mild cognitive impairment
|subjective cognitive impairment
|Spatial navigation measured by the Floor Maze Test in patients with subjective cognitive impairment, mild cognitive impairment, and mild Alzheimer's disease