• Anti-inflammatory MicroRNAs and their potential for inflammatory diseases treatment 

      Tahamtan, Alireza; Teymoori-Rad, Majid; Nakstad, Britt; Salimi, Vahid (Frontiers in immunology;9, Journal article; Peer reviewed, 2018-06-25)
      Inflammation is a complicated biological and pathophysiological cascade of responses to infections and injuries, and inflammatory mechanisms are closely related to many diseases. The magnitude, the complicated network of ...
    • Assessing severity in pediatric pneumonia. Predictors of the need for major medical interventions 

      Berg, Are Stuwitz; Inchley, Christopher; Fjærli, Hans Olav; Leegaard, Truls Michael; Nakstad, Britt (Pediatric emergency care;, Journal article; Peer reviewed, 2017)
      Objective: The aim of this study was to determine potential predictors of the need for major medical interventions in the context of assessing severity in pediatric pneumonia. Methods: This was a prospective, cohort ...
    • Chest Compression Quality in a Newborn Manikin: A Randomized Crossover Trial 

      Solevåg, Anne Lee; Cheung, Po-Yin; Li, Elliott; Xue, Sarah Zhenchun; O'Reilly, Megan; Fu, Bo; Zheng, Bin; Schmölzer, Georg (IEEE journal of translational engineering in health and medicine;6, Journal article; Peer reviewed, 2018-09-04)
      The objective of this paper was to examine the changes in applied force and rate of chest compression (CC) during 5 min of CC with a target CC rate of 90/min (CC90) or 120/min (CC120) with and without metronome guidance ...
    • Childhood Fat and Lean Mass: Differing Relations to Vascular Structure and Function at Age 8 to 9 Years 

      Sletner, Line; Mahon, Pamela; Crozier, Sarah R.; Inskip, Hazel M.; Godfrey, Keith M.; Chiesa, Scott; Bhowruth, Devina J.; Charakida, Marietta; Deanfield, John; Cooper, Cyrus; Hanson, Mark (Arteriosclerosis, thrombosis, and vascular biology;38(10), Journal article; Peer reviewed, 2018-08-30)
      Objective— Childhood body mass index (BMI) has been related to vascular structure and function. However, little is known about the differing contributions of fat and lean mass to this relationship. Our objectives were to ...
    • Clinical features and inflammatory markers in pediatric pneumonia: a prospective study 

      Inchley, Christopher; Fjærli, Hans Olav; Leegaard, Truls Michael; Lindbæk, Morten; Nakstad, Britt (European journal of pediatrics;176(5), Journal article; Peer reviewed, 2017-03-09)
      Abstract In this prospective, observational study on previously healthy children <18 years, we aimed to study the diagnostic ability of clinical features and inflammatory markers to (i) predict pathologic chest radiography ...
    • Early warning- and track and trigger systems for newborn infants: A review 

      Mortensen, Nicolay; Augustsson, Johan Henrik; Ulriksen, Jorunn; Hinna, Unni Tveit; Schmölzer, Georg M. (Journal of Child Health Care;21(1), Journal article; Peer reviewed, 2017-01-19)
      Tools for clinical assessment and escalation of observation and treatment are insufficiently established in the newborn population. We aimed to provide an overview over early warning- and track and trigger systems for ...
    • Evidence on Adrenaline Use in Resuscitation and Its Relevance to Newborn Infants: A Non-Systematic Review 

      Pinto, M; Solevåg, Anne Lee; O´Reilly, Megan; Aziz, Khalid; Cheung, Po-Yin; Schmölzer, Georg M (Neonatology;111(1), Journal article; Peer reviewed, 2016-12)
      AIM: Guidelines for newborn resuscitation state that if the heart rate does not increase despite adequate ventilation and chest compressions, adrenaline administration should be considered. However, controversy exists ...
    • Optimal chest compression rate and compression to ventilation ratio in delivery room resuscitation: Evidence from newborn piglets and neonatal manikins 

      Solevåg, Anne Lee; Schmölzer, Georg M (Frontiers in Pediatrics;5, Journal article; Peer reviewed, 2017-01-23)
      Cardiopulmonary resuscitation (CPR) duration until return of spontaneous circulation (ROSC) influences survival and neurologic outcomes after delivery room (DR) CPR. High quality chest compressions (CC) improve cerebral ...
    • Optimal conventional mechanical ventilation in full-term newborns: A systematic review 

      Solberg, Marianne Trygg; Solevåg, Anne Lee; Clarke, Sara (Advances in Neonatal Care;18(6), Journal article; Peer reviewed, 2018-12)
      Background: Most studies examining the best mechanical ventilation strategies in newborn infants have been performed in premature infants with respiratory distress syndrome. Purpose: To identify and synthesize the ...
    • Optimizing home hospital health service delivery in norway using a combined geographical information system, agent based, discrete event simulation model 

      Viana, Joe; Ziener, Vigids Margrethe; Ponton, Irene Gynnild; Holhjem, Marita Sommer; Thørgersen, Lisa Johanne; Simonsen, Tone Breines (Proceedings of the 2017 Winter Simulation Conference;pp. 128, Conference object; Journal article; Peer reviewed, 2018-01-08)
      Home hospital services; provide some hospital level services at the patient's residence. The services include for example: palliative care, administering chemotherapy drugs, changing dressings and care for newborns. The ...
    • Preserved endothelial function in young adults with type 1 diabetes 

      Heier, Martin; Espeland, Cathrine Nygaard; Brunborg, Cathrine; Seljeflot, Ingebjørg; Margeirsdottir, Hanna Dis; Hanssen, Kristian Folkvord; Fugleseth, Drude Merete; Dahl-Jørgensen, Knut (PLoS ONE;13(10), Journal article; Peer reviewed, 2018-10-25)
      Background and aim Endothelial dysfunction is involved in the pathogenesis of atherosclerosis and is typically present in older adults with type 1 diabetes (T1D). In young adults, we aimed to assess the impact of T1D on ...
    • Pulseless electrical activity: A misdiagnosed entity during asphyxia in newborn infants? 

      Patel, Sparsh; Cheung, Po-Yin; Solevåg, Anne Lee; Barrington, Keith J; Kamlin, C. Omar Farouk; Davis, Peter G.; Schmölzer, Georg Marcus (Archives of Disease in Childhood-Fetal and Neonatal Edition;104(2), Journal article; Peer reviewed, 2018-06-12)
      Background The 2015 neonatal resuscitation guidelines added ECG as a recommended method of assessment of an infant’s heart rate (HR) when determining the need for resuscitation at birth. However, a recent case report raised ...
    • A review of oxygen use during chest compressions in Newborns-A meta-analysis of animal data 

      Garcia-Hidalgo, Catalina; Cheung, Po-Yin; Vento, Máximo; O´Reilly, Megan; Saugstad, Ola Didrik; Schmölzer, Georg M. (Frontiers in pediatrics;6, Journal article; Peer reviewed, 2018-12-18)
      Background: International consensus statements for resuscitation of newborn infants recommend provision of 100% oxygen once chest compressions are required. However, 100% oxygen exacerbates reperfusion injury and reduces ...
    • Right and left ventricular function in hospitalized children with respiratory syncytial virus infection 

      Horter, Thorsten; Nakstad, Britt; Ashtari, Omid; Solevåg, Anne Lee (Infection and Drug Resistance;10, Journal article; Peer reviewed, 2017-11-07)
      Background: Extrapulmonary manifestations including cardiac dysfunction have been demonstrated in children with respiratory syncytial virus (RSV) infection requiring intensive care. The aim of this study was to examine ...
    • Vitamin D levels during pregnancy and associations with birth weight and body composition of the newborn: A longitudinal multiethnic population-based study 

      Eggemoen, Åse Ruth; Jenum, Anne Karen; Mdala, Ibrahimu; Knutsen, Kirsten Irene Valebjørg; Lagerløv, Per; Sletner, Line (British Journal of Nutrition;117(7), Journal article; Peer reviewed, 2017-04-14)
      We investigated associations between serum 25-hydroxyvitamin D (25(OH)D) in pregnancy and birth weight and other neonatal anthropometric measures. The present study was a population-based, multiethnic cohort study of 719 ...