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    • Subjective cognitive impairment is a predominantly benign condition in memory clinic patients followed for 6 years: The Gothenburg-oslo MCI Study 

      Hessen, Erik; Eckerström, Marie; Nordlund, Arto; Almdahl, Ina; Stålhammar, Jacob; Bjerke, Maria; Eckerström, Carl; Göthlin, Mattias; Fladby, Tormod; Reinvang, Ivar; Wallin, Anders (Dementia and Geriatric Cognitive Disorders Extra;7(1), Journal article; Peer reviewed, 2017-02-02)
      Background/Aims: In the quest for prevention or treatment, there is a need to find early markers for preclinical dementia. This study observed memory clinic patients with subjective cognitive impairment (SCI) and normal ...

    • Surgical site infection after hip fracture – mortality and risk factors: an observational cohort study of 1,709 patients 

      Pullmann, Christian Thomas; Dahl, Fredrik Andreas; Røtterud, Jan H; Gjertsen, Jan Erik; Årøen, Asbjørn (Acta Orthopaedica;1-6, Journal article; Peer reviewed, 2020-01-24)
      Abstract Background and purpose — Surgical site infection (SSI) is a devastating complication of hip fracture surgery. We studied the contribution of early deep SSI to mortality after hip fracture surgery and the risk ...

    • A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America 

      Rossi, Benedito Mauro; Palmero, Edenir Inêz; López-Kostner, Francisco; Sarroca, Carlos; Vaccaro, Carlos Alberto; Spirandelli, Florencia; Ashton-Prolla, Patricia; Rodriguez, Yenni; Galvão, Henrique de Campos Reis; Reis, Rui Manuel; dePaula, André Escremim; Romagnolo, Luis Gustavo Capochin; Alvarez, Karin; Valle, Adriana Della; Neffa, Florencia; Kalfayan, Pablo German; Spirandelli, Enrique; Chialina, Sergio; Angulo, Melva Gutiérrez; Castro-Mujica, Maria del Carmen; de Monte, Julio Sanchez; Quispe, Richard; de Silva, Sabrina Daniela; Rossi, Norma Teresa; Barletta-Carrillo, Claudia; Revollo, Susann; Taborga, Ximena; Morillas, L. Lena; Tubeuf, Hélène; Monteiro-Santos, Erika Maria; Piñero, Tamara Alejandra; Dominguez-Barrera, Constantino; Wernhoff, Patrik; Martins, Alexandra; Hovig, Eivind; Møller, Pål; Valentin, Mev Dominguez (BMC cancer;17(1), Journal article; Peer reviewed, 2017-09-05)
      Background Genetic counselling and testing for Lynch syndrome (LS) have recently been introduced in several Latin America countries. We aimed to characterize the clinical, molecular and mismatch repair (MMR) variants ...

    • Symptoms of premenstrual syndrome in female migraineurs with and without menstrual migraine 

      Vetvik, Kjersti; MacGregor, E. Anne; Lundqvist, Anders Christofer; Russell, Michael Bjørn (The Journal of Headache and Pain;19(1), Journal article; Peer reviewed, 2018-10-17)
      Menstrual migraine (MM) and premenstrual syndrome (PMS) are two conditions linked to specific phases of the menstrual cycle. The exact pathophysiological mechanisms are not fully understood, but both conditions are ...

    • Tailored treatment of colorectal cancer: Surgical, molecular, and genetic considerations 

      Augestad, Knut Magne; Merok, Marianne Aarstad; Ignjatovic, Dejan (Clinical Medicine Insights: Oncology;11, Journal article; Peer reviewed, 2017-02-16)
      Colorectal cancer (CRC) is a complex cancer disease, and approximately 40% of the surgically cured patients will experience cancer recurrence within 5 years. During recent years, research has shown that CRC treatment should ...

    • Test Item 

      Young, Hayden (Chapter, 2017)

    • Tested and reported executive problems in children and youth epilepsy 

      Hessen, Erik; Alfstad, Kristin Åshild; Torgersen, Halvor S.; Lossius, Morten (Brain and Behavior;8(5), Journal article; Peer reviewed, 2018-04-16)
      Objectives Executive problems in children and youth with epilepsy influence their ability to handle important aspects of daily life activities. The present study sought to explore factors associated with executive problems ...

    • Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations 

      Møller, Elen Kristine; Nord, Silje; Wedge, David C.; Lingjærde, Ole Christian; Silwal-Pandit, Laxmi; Gythfeldt, Hedda; Vollan, Hans Kristian Moen; Fleischer, Thomas; Krohn, Marit; Schlichting, Ellen; Borgen, Elin; Garred, Øystein; Holmen, Marit Muri; Wist, Erik; Naume, Bjørn; Van Loo, Peter; Børresen-Dale, Anne-Lise; Engebråten, Olav; Kristensen, Vessela N. (Genome medicine;10(1), Journal article; Peer reviewed, 2018-11-29)
      Background Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) and inhibits its ...

    • Trajectories of Depression in Late Life: A 1-Year Follow-Up Study 

      Borza, Tom; Engedal, Knut Arne; Bergh, Sverre; Saltyte-Benth, Jurate; Selbæk, Geir (Dementia and geriatric cognitive disorders;43(3-4), Journal article; Peer reviewed, 2017-04)
      Aims: To investigate the prognosis of depression in late life (DLL) in terms of the course of depression over 1 year and assess clinical factors related to the prognosis. Methods: We performed an observational, multicenter, ...

    • Trolly dilemmas fail to predict ethical judgment in a hypothetical vaccination context 

      Dahl, Fredrik Andreas; Oftedal, Gry (Journal of Empirical Research on Human Research Ethics;14(1), Journal article; Peer reviewed, 2018-11-01)
      We investigated whether the responses of 68 ethics committee members and staff to trolley dilemmas could predict their responses to research ethics problems concerning vaccine trials. Trolley dilemmas deal with the issue ...

    • Tumor-associated macrophages are strongly related to vascular invasion, non-luminal subtypes, and interval breast cancer 

      Klingen, Tor Audun; Chen, Ying; Aas, Hans; Wik, Elisabeth; Akslen, Lars A (Human Pathology;69, Journal article; Peer reviewed, 2017-11)
      Tumor-associated macrophages (TAM) resemble M2 macrophages, promote tumor invasion and show strong expression of CD163 in breast cancer. We here investigated the association between CD163-positive macrophages and vascular ...

    • Two novel connexin32 mutations cause early onset X-linked Charcot-Marie-Tooth disease 

      Braathen, Geir Julius; Sand, Jette C.; Bukholm, Geir; Russell, Michael B. (BMC neurology;7(1), Journal article; Peer reviewed, 2007-07-09)
      Background X-linked Charcot-Marie Tooth (CMT) is caused by mutations in the connexin32 gene that encodes a polypeptide which is arranged in hexameric array and form gap junctions. Methods We describe two novel ...

    • An update on cladribine for relapsing-remitting multiple sclerosis 

      Holmøy, Trygve; Torkildsen, Øivind Fredvik; Myhr, Kjell-Morten (Expert Opinion on Pharmacotherapy;18(15), Journal article; Peer reviewed, 2017-09-11)
      INTRODUCTION: Despite recent progress, currently available therapies for relapsing remitting multiple sclerosis (MS) are only partly effective, and their use is limited by tolerability and safety issues, as well as high ...

    • The usage of fasting glucose and glycated hemoglobin for the identification of unknown type 2 diabetes in high risk patients with morbid obesity 

      Valderhaug, Tone Gretland; Sharma, Archana; Kravdal, Gunnhild; Rønningen, Reidun; Nermoen, Ingrid (Scandinavian journal of clinical and laboratory investigation;77(7), Journal article; Peer reviewed, 2017-07-17)
      Background: In spite of increased vigilance of undiagnosed type 2 diabetes (DM2), the prevalence of unknown DM2 in subjects with morbid obesity is not known. Aim: To assess the prevalence of undiagnosed DM2 and compare ...

    • The Valgent4 protocol: Robust analytical and clinical validation of 11 HPV assays with genotyping on cervical samples collected in SurePath medium 

      Bonde, Jesper; Ejegod, Ditte Møller; Cuschieri, Kate; Dillner, Joakim; Heideman, Daniëlle A. M.; Quint, Wim; Ribas, Miguel Angel pavon; Padalko, Elizaveta; Christiansen, Irene Kraus; Xu, Lan; Arbyn, Marc (Journal of Clinical Virology;108, Journal article; Peer reviewed, 2018-09-14)
      Background The VALidation of HPV GENoyping Tests (VALGENT) is an international initiative designed to validate HPV assays with genotyping capability. The VALGENT4 protocol differs from previous VALGENT installments as the ...

    • Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification 

      Rutkovskiy, Arkady; Malashicheva, Anna; Sullivan, Gareth; Bogdanova, Mariia; Kostareva, Anna; Stensløkken, Kåre-Olav; Fiane, Arnt E; Vaage, Ingvar Jarle (Journal of The American Heart Association;6(9), Journal article; Peer reviewed, 2017-09-22)
      Aortic valve stenosis due to calcification of the valve leaflets is the most common valve disease in the developed world. It is the third leading cause of cardiovascular disease.1 Risk factors include male gender, smoking, ...

    • Variations in patient safety climate and perceived quality of collaboration between professions in out-of-hours care 

      Klemenec-Ketis, Zalika; Deilkås, Ellen C Tveter; Hofoss, Dag; Bondevik, Gunnar Tschudi (Journal of Multidisciplinary Healthcare;10, Journal article; Peer reviewed, 2017-11-09)
      Purpose: To get an overview of health care workers perceptions of patient safety climates and the quality of collaboration in Slovenian out-of-hours health care (OOHC) between professional groups. Materials and methods: ...

    • Vertebral Bone Mineral Density Measured by Quantitative Computed Tomography With and Without a Calibration Phantom: A Comparison Between 2 Different Software Solutions 

      Therkildsen, Josephine; Thygesen, Jesper; Winther, Simon; Svensson, My Hanna Sofie; Hauge, Ellen-Margrethe; Bøttcher, Morten; Ivarsen, Per; Jørgensen, Hanne Skou (Journal of Clinical Densitometry;21(3), Journal article; Peer reviewed, 2018-03-27)
      Quantitative computed tomography (CT) can be used to quantify bone mineral density (BMD) in the spine from clinical CT scans. We aimed to determine agreement and precision of BMD measurements by 2 different methods: ...

    • Vitamin D levels during pregnancy and associations with birth weight and body composition of the newborn: A longitudinal multiethnic population-based study 

      Eggemoen, Åse Ruth; Jenum, Anne Karen; Mdala, Ibrahimu; Knutsen, Kirsten Irene Valebjørg; Lagerløv, Per; Sletner, Line (British Journal of Nutrition;117(7), Journal article; Peer reviewed, 2017-04-14)
      We investigated associations between serum 25-hydroxyvitamin D (25(OH)D) in pregnancy and birth weight and other neonatal anthropometric measures. The present study was a population-based, multiethnic cohort study of 719 ...

    • What are “good outcomes” in Public mental health settings? A qualitative exploration of clients’ and therapists’ experiences 

      Moltu, Christian; Stefansen, Jon; Nøtnæs, Jan Christian; Skjølberg, Åse; Veseth, Marius (International Journal of Mental Health Systems;11(1), Journal article; Peer reviewed, 2017-01-14)
      Background The mental health field sees a surge of interest in Routine Outcome Monitoring, mandated by a wish to help better those not-on-track to recovery. What constitutes positive outcomes for these patients is not ...