Blar i Fakultet for helsevitenskap (HV) på tidsskrift "Scientific Reports"

Viser treff 1-15 av 15

    • Assessing generalisability of deep learning-based polyp detection and segmentation methods through a computer vision challenge 

      Ali, Sharib; Ghatwary, Noha; Jha, Debesh; Isik-Polat, Ece; Polat, Gorkem; Yang, Cheng; Li, Wuyang; Galdran, Adrian; Ballester, Miguel Angel Gonzalez; Thambawita, Vajira L B; Hicks, Steven; Poudel, Sahadev; Lee, Sang-Woong; Jin, Ziyi; Gan, Tianyuan; Yu, Chenghui; Yan, JiangPeng; Yeo, Doyeob; Lee, Hyunseok Lee; Tomar, Nikhil Kumar; Haitham, Mahmood; Ahmed, Amr; Riegler, Michael Alexander; Daul, Christian; Halvorsen, Pål; Rittscher, Jens; Salem, Osama E.; Lamarque, Dominique; Cannizzaro, Renato; Realdon, Stefano; de Lange, Thomas; East, James E (Peer reviewed; Journal article, 2024)
      Polyps are well‑known cancer precursors identified by colonoscopy. However, variability in their size, appearance, and location makes the detection of polyps challenging. Moreover, colonoscopy surveillance and removal ...

    • Body composition and physical fitness in adults born small for gestational age at term: a prospective cohort study 

      Matre, Maria; Mehl, Cathrin Vano; Benum, Silje Dahl; Jussinniemi, Laura; Kajantie, Eero Olavi; Evensen, Kari Anne Indredavik (Peer reviewed; Journal article, 2023)
      There is lack of research on body composition and physical fitness in individuals born small for gestational age (SGA) at term entering mid-adulthood. We aimed to investigate these outcomes in adults born SGA at term. ...

    • Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement 

      Vigeland, Maria Dehli; Flåm, Siri Tennebø; Vigeland, Magnus Dehli; Espeland, Ansgar; Kristoffersen, Per Martin; Vetti, Nils; Wigemyr, Monica; Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Schistad, Ellina Iordanova; Haugen, Anne Julsrud; Johanessen, Anne Froholdt; Skouen, Jan Sture; Zwart, John Anker Henrik; Storheim, Kjersti; Pedersen, Linda Margareth; Lie, Benedicte Alexandra (Scientific Reports;12, Article number: 215 (2022), Peer reviewed; Journal article, 2022-01-07)
      Disability and distress caused by chronic low back pain (LBP) lacking clear pathoanatomical explanations cause huge problems both for patients and society. A subgroup of patients has Modic changes (MC), identifable by MRI ...

    • The effect of toll-like receptor ligands on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells 

      Tingstad, Ragna Husby; Norheim, Frode Amador; Haugen, Fred; Feng, Yuan Zeng; Tunsjø, Hege; Thoresen, G. Hege; Rustan, Arild Christian; Charnock, Colin; Aas, Vigdis (Scientific Reports;11, Article number: 24219 (2021), Peer reviewed; Journal article, 2021-12-20)
      Skeletal muscle plays an important role in glycaemic control and metabolic homeostasis, making it a tissue of interest with respect to type 2 diabetes mellitus. The aim of the present study was to determine if ligands of ...

    • Enhancing investigative interview training using a child avatar system: a comparative study of interactive environments 

      Zohaib Hassan, Syed; Shafiee Sabet, Saeed; Riegler, Michael Alexander; Baugerud, Gunn Astrid; Ko, Hayley Manalang; Salehi, Pegah; Røed, Ragnhild Klingenberg; Sinkerud Johnson, Miriam; Halvorsen, Pål (Peer reviewed; Journal article, 2023)
      The impact of investigative interviews by police and Child Protective Services (CPS) on abused children can be profound, making effective training vital. Quality in these interviews often falls short and current training ...

    • Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders 

      Aas, Monica; Andreassen, Ole; Gjerstad, Johannes; Rødevand, Linn; Hjell, Gabriela; Johansen, Ingrid Torp; Lunding, Synve Hoffart; Ormerod, Monica Bettina E. Greenwood; Lagerberg, Trine Vik; Steen, Nils Eiel; Djurovic, Srdjan; Akkouh, Ibrahim Ahmed (Peer reviewed; Journal article, 2023)
      Exposure to early life trauma increases the risk of psychopathology later in life. Here we investigated if ANK3 mRNA levels influence the relationship between childhood trauma experiences and clinical characteristics in ...

    • Knockdown of SPRY4 and SPRY4-IT1 inhibits cell growth and phosphorylation of Akt in human testicular germ cell tumours 

      Das, Mrinal Kumar; Furu, Kari; Evensen, Herman Sebastian Folkestad; Haugen, Øyvind Pernell; Haugen, Trine B. (Scientific Reports;Volume 8, Article number: 2462 (2018), Journal article; Peer reviewed, 2018-02-06)
      Testicular germ cell tumour (TGCT) is the most common cancer in young men in large parts of the world, but the aetiology is mainly unknown. Genome-wide association studies have so far identified about 50 susceptibility ...

    • Mortality and microbial diversity after allogenic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial 

      Skaarud, Kristin Aneta Joan; Hov, Johannes Espolin Roksund; Hansen, Simen Hyll; Kummen, Martin; Valeur, Jørgen; Seljeflot, Ingebjørg; Bye, Asta; Paulsen, Vemund; Lundin, Knut Erik Aslaksen; Trøseid, Marius; Tjønnfjord, Geir Erland; Iversen, Per Ole (Scientific Reports;11:11593, Peer reviewed; Journal article, 2021-06-02)
      Gut mucosal barrier injury is common following allogeneic hematopoietic stem cell transplantation (allo-HSCT) and associated with poor clinical outcomes. Diet is critical for microbial diversity, but whether nutritional ...

    • Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study 

      Tashbayev, Behzod; Garen, Torhild Oddveig; Palm, Øyvind; Chen, Xiangjun; Herlofson, Bente Brokstad; Young Vik, Alix Rosslyn; Hove, Lene Hystad; Rykke, Morten; Singh, Preet Bano; Aqrawi, Lara Adnan; Utheim, Øygunn Aass; Utheim, Tor Paaske; Jensen, Janicke Cecilie Liaaen (Scientific Reports;10, Article number: 2063 (2020), Journal article; Peer reviewed, 2020-02-07)
      Understanding the impact of the disease on quality of life is crucial in patient management. In this cross-sectional study, general and oral health-related quality of life questionnaires, and thorough examinations of oral ...

    • A preliminary study of the use of MinION sequencing to specifcally detect Shiga toxin‑producing Escherichia coli in culture swipes containing multiple serovars of this species 

      Tunsjø, Hege; Ullmann, Ingvild Falkum; Charnock, Colin (Peer reviewed; Journal article, 2023)
      An important challenge relating to clinical diagnostics of the foodborne pathogen Shiga toxin-producing E. coli (STEC), is that PCR-detection of the shiga-toxin gene (stx) in DNA from stool samples can be accompanied by a ...

    • A preliminary study on the potential of Nanopore MinION and Illumina MiSeq 16S rRNA gene sequencing to characterize building-dust microbiomes 

      Nygaard, Anders Benteson; Tunsjø, Hege; Meisal, Roger; Charnock, Colin (Scientific Reports;10, Article number: 3209 (2020), Journal article; Peer reviewed, 2020-01-30)
      There is a growing awareness of the importance of indoor microbiomes for human health. Given their complexity, these microbiomes can only be adequately surveyed using high throughput sequencing techniques. Oxford Nanopore's ...

    • TaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration 

      Lagström, Sonja; Umu, Sinan Uğur; Lepistö, Maija; Ellonen, Pekka; Meisal, Roger; Christiansen, Irene Kraus; Ambur, Ole Herman; Rounge, Trine Ballestad (Scientific Reports;9, Article number: 524 (2019), Journal article; Peer reviewed, 2018-11-26)
      HPV genomic variability and chromosomal integration are important in the HPV-induced carcinogenic process. To uncover these genomic events in an HPV infection, we have developed an innovative and cost-effective sequencing ...

    • Transcription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancer 

      Kiselev, Yury; Andersen, Sigve; Johannessen, Charles; Fjukstad, Bjørn; Olsen, Karina Standahl; Stenvold, Helge; Al-Saad, Samer; Dønnem, Tom; Richardsen, Elin; Bremnes, Roy M.; Busund, Lill-Tove (Scientific Reports;Volume 8, Article number: 5059 (2018), Journal article; Peer reviewed, 2018-03-22)
      Lung cancer is the leading cause of cancer deaths. Novel predictive biomarkers are needed to improve treatment selection and more accurate prognostication. PAX6 is a transcription factor with a proposed tumour suppressor ...

    • Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease 

      Tashbayev, Behzod; Utheim, Tor Paaske; Utheim, Øygunn Aass; Ræder, Sten; Jensen, Janicke Cecilie Liaaen; Yazdani, Mazyar; Lagali, Neil Satish; Vitelli, Valeria; Dartt, Darlene Ann; Chen, Xiangjun (Scientific Reports;10, Article number: 5542 (2020), Journal article; Peer reviewed, 2020-03-26)
      The prevalence of dry eye disease is high worldwide and poses a great burden on patients’ daily lives. Accurate diagnosis of the disease is important, and it requires application of various methods. Hyperosmolarity is ...

    • Utilization of lactic acid in human myotubes and interplay with glucose and fatty acid metabolism 

      Lund, Jenny; Aas, Vigdis; Tingstad, Ragna Husby; Van Hees, Alfons; Nikolic, Natasa (Scientific Reports;8, Article number: 9814 (2018), Journal article; Peer reviewed, 2018-06-29)
      Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now recognized as an energy source in skeletal muscles. While lactate metabolism has been extensively studied in vivo, underlying cellular ...