Browsing Fakultet for helsevitenskap (HV) by Author "Fallon, Marie T."
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Deterioration in Muscle Mass and Physical Function Differs According to Weight loss History in Cancer Cachexia
Stene, Guro Birgitte; Balstad, Trude Rakel; Leer, Anne Silja Mäkitalo; Bye, Asta; Kaasa, Stein; Fallon, Marie T.; Laird, Barry J; Maddocks, Matthew; Solheim, Tora Skeidsvoll (Cancers;Volume 11, Issue 12, Journal article; Peer reviewed, 2019-11-22)Background: Muscle mass and physical function (PF) are common co-primary endpoints in cancer cachexia trials, but there is a lack of data on how these outcomes interact over time. The aim of this secondary analysis of data ... -
Deterioration in muscle mass and physical function differs according to weight loss history in cancer cachexia
Stene, Guro Birgitte; Balstad, Trude Rakel; Leer, Anne Silja Mäkitalo; Bye, Asta; Kaasa, Stein; Fallon, Marie T.; Laird, Barry J; Maddocks, Matthew; Solheim, Tora Skeidsvoll (Cancers 2019;11(12), Journal article; Peer reviewed, 2019)Background: Muscle mass and physical function (PF) are common co-primary endpoints in cancer cachexia trials, but there is a lack of data on how these outcomes interact over time. The aim of this secondary analysis of data ... -
Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series
McDonald, James; Sayers, Judith; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Baracos, Vickie; Brown, Leo; Bye, Asta; Dajani, Olav; Dolan, Ross; Fallon, Marie T.; Fraser, Eilidh; Griel, Christine; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jamal-Hanjani, Mariam; Jakobsen, Gunnhild; Kaasa, Stein; McMillan, Donald; Maddocks, Matthew; Philips, Iain; Ottestad, Inger; Reid, Kieran F.; Sousa, Mariana S.; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Skipworth, Richard J. E.; Solheim, Tora S; Laird, Barry J (Peer reviewed; Journal article, 2023)In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, ... -
Power comparisons and clinical meaning of outcome measures in assessing treatment effect in cancer cachexia: secondary analysis from a randomised pilot multimodal intervention trial
Balstad, Trude Rakel; Brunelli, Cinzia; Pettersen, Caroline Hild; Schønberg, Svanhild Margrethe Arentz; Skorpen, Frank; Fallon, Marie T.; Kaasa, Stein; Bye, Asta; Laird, Barry J. A.; Stene, Guro Birgitte; Solheim, Tora Skeidsvoll (Frontiers in Nutrition; January 2021 | Volume 7 | Article 602775, Journal article; Peer reviewed, 2020-01-14)Background: New clinical trials in cancer cachexia are essential, and outcome measures with high responsiveness to detect meaningful changes are crucial. This secondary analysis from a multimodal intervention trial estimates ...