• Antiepileptic and antidepressive polypharmacy in patients with multiple sclerosis. 

      Beiske, Georg; Holmøy, Trygve; Beiske, Antonie Giæver; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Multiple sclerosis international;2015, Journal article; Peer reviewed, 2015)
      Objective. Patients with multiple sclerosis (MS) are often suffering from neuropathic pain. Antiepileptic drugs (AEDs) and tricyclic antidepressants (TCAs) are commonly used and are susceptible to be involved in drug ...
    • Best mulig behandling med antiepileptika for den enkelte pasient! 

      Landmark, Cecilie Johannessen; Baftiu, Arton; Burns, Margrete Larsen; Mevåg, Morten A; Feet, Silje Andrea; Reiter, Lillian; Johannessen, Svein Ivar (Norsk Farmaceutisk Tidsskrift;(2), Journal article; Peer reviewed, 2015)
      Hensikt «Best mulig behandling med antiepileptika for den enkelte pasient!» er et avgjørende mål for behandling av pasienter med epilepsi, men også for stadig nye pasientgrupper som bruker antiepileptika. Hensikten med ...
    • Clinical experience combined with therapeutic drug monitoringof lacosamide 

      Svendsen, Torleiv; Brodtkorb, Eylert; Baftiu, Arton; Lossius, Morten; Nakken, Karl Otto; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Acta Neurologica Scandinavica;Volume 141, Issue 4, Journal article; Peer reviewed, 2019-12-14)
      Objective: Lacosamide (LCM) is an antiepileptic drug (AED) with insufficient clinical experience in patients with intellectual disability (ID). They often have more severe epilepsy with comorbidities. The objective was to ...
    • Long-term follow-up with therapeutic drug monitoring of antiepileptic drugs in patients with juvenile myoclonic epilepsy 

      Landmark, Cecilie Johannessen; Fløgstad, Ida; Baftiu, Arton; Syvertsen, Marte Roa; Enger, Ulla Helene; Johannessen, Svein Ivar (Epilepsy Research;Volume 155, September 2019, Journal article; Peer reviewed, 2019-05-30)
      Background and purpose: Patients with juvenile myoclonus epilepsy (JME) may experience uncontrolled seizures and challenges regarding adherence. Implementation of therapeutic drug monitoring (TDM) may contribute to ...
    • Pharmacokinetic variability and clinical use of lacosamide in children and adolescents in Denmark and Norway 

      Burns, Margrete Larsen; Nikanorova, Marina; Baftiu, Arton; Rasmussen, Jan Borg; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Therapeutic Drug Monitoring;41 (3): 340–347, JUNE 2019, Journal article; Peer reviewed, 2019-01-01)
      Background: The indication for the antiepileptic drug (AED) lacosamide (LCM) was recently extended to include children from the age of four. Real-life data on the use and serum concentrations of LCM in children and ...
    • Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines 

      Reimers, Arne; Berg, Jon Andsnes; Burns, Margrete Larsen; Brodtkorb, Eylert; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Journal article; Peer reviewed, 2018)
      Background and objective: Laboratories sometimes use different reference ranges for the same antiepileptic drug (AED), particularly for new and poorly investigated drugs. This may contribute to misunderstandings, concerns ...
    • A retrospective review of changes and challenges in the use ofantiseizure medicines in Dravet syndrome in Norway 

      Lund, Caroline; Burns, Margrete Larsen; Bjørnvold, Marit; Sætre, Erik; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen; Heger, Katrine (Epilepsia Open;Volume 5, Issue 3, September 2020, Journal article; Peer reviewed, 2020-06-26)
      Objective: Dravet syndrome is a developmental and epileptic encephalopathy characterized by severe and drug-resistant seizures in early childhood, followed by developmental delay. The purpose of this study was to investigate ...
    • Treatment and challenges with antiepileptic drugs in patients with juvenile myoclonic epilepsy 

      Landmark, Cecilie Johannessen; Fløgstad, Ida; Syvertsen, Marte Roa; Baftiu, Arton; Enger, Ulla Helene; Koht, Jeanette; Johannessen, Svein Ivar (Epilepsy & Behavior;Volume 98, Part A, September 2019, Journal article; Peer reviewed, 2019-07-19)
      Background: Patients with juvenile myoclonic epilepsy (JME) may have uncontrolled seizures. The purpose of this study was to investigate the use and challenges with antiepileptic drugs (AEDs) and the patients' view of ...