Browsing ODA Open Digital Archive by Author "Balstad, Trude Rakel"

Now showing items 1-12 of 12

    • Biomarker endpoints in cancer cachexia clinical trials: Systematic Review 5 of the cachexia endpoint series 

      Yule, Michael S.; Thompson, Joshua; Leesahatsawat, Khachonphat; Sousa, Mariana S.; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Brown, Leo R.; Bye, Asta; Dajani, Olav; Fallon, Marie; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; McDonald, James; McGovern, Josh; Roeland, Eric J.; Sayers, Judith; Skipworth, Richard J.E.; Ottestad, Inger; Philips, Iain; Simpson, Melanie Rae; Solheim, Tora S; Vagnildhaug, Ola Magne; McMillan, Donald; Laird, Barry J; Dolan, Ross D. (Peer reviewed; Journal article, 2024)
      Regulatory agencies require evidence that endpoints correlate with clinical benefit before they can be used to approve drugs. Biomarkers are often considered surrogate endpoints. In cancer cachexia trials, the measurement ...

    • Cancer cachexia: Rationale for the MENAC (Multimodal - Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial 

      Solheim, Tora Skeidsvoll; Laird, Barry J. A.; Balstad, Trude Rakel; Bye, Asta; Stene, Guro Birgitte; Baracos, Vickie; Strasser, Florian; Griffiths, Gareth; Maddocks, Matthew; Fallon, Marie; Kaasa, Stein; Fearon, Kenneth (BMJ Supportive & Palliative Care;Volume 8, Issue 3, Journal article; Peer reviewed, 2018-02-09)
      Cancer cachexia is a multifactorial syndrome characterized by an on-going loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer ...

    • Deterioration in Muscle Mass and Physical Function Differs According to Weight loss History in Cancer Cachexia 

      Stene, Guro Birgitte; Balstad, Trude Rakel; Leer, Anne Silja Mäkitalo; Bye, Asta; Kaasa, Stein; Fallon, Marie T.; Laird, Barry J; Maddocks, Matthew; Solheim, Tora Skeidsvoll (Cancers;Volume 11, Issue 12, Journal article; Peer reviewed, 2019-11-22)
      Background: Muscle mass and physical function (PF) are common co-primary endpoints in cancer cachexia trials, but there is a lack of data on how these outcomes interact over time. The aim of this secondary analysis of data ...

    • Deterioration in muscle mass and physical function differs according to weight loss history in cancer cachexia 

      Stene, Guro Birgitte; Balstad, Trude Rakel; Leer, Anne Silja Mäkitalo; Bye, Asta; Kaasa, Stein; Fallon, Marie T.; Laird, Barry J; Maddocks, Matthew; Solheim, Tora Skeidsvoll (Cancers 2019;11(12), Journal article; Peer reviewed, 2019)
      Background: Muscle mass and physical function (PF) are common co-primary endpoints in cancer cachexia trials, but there is a lack of data on how these outcomes interact over time. The aim of this secondary analysis of data ...

    • Dietary treatment of weight loss in patients with advanced cancer and cachexia: A systematic literature review 

      Balstad, Trude Rakel; Solheim, Tora Skeidsvoll; Strasser, Florian; Kaasa, Stein; Bye, Asta (Journal article; Peer reviewed, 2014-08)
      Purpose A systematical literature review evaluating the effect of dietary counseling in treating weight loss and improving energy intake in patients with advanced cancer with different stages of cachexia. Principal ...

    • Exercise and nutrition interventions in patients with head and neck cancer during curative treatment: a systematic review and meta-analysis 

      Oldervoll, Line Merethe; Bye, Asta; Sandmæl, Jon Arne; Solheim, Tora Skeidsvoll; Stene, Guro Birgitte; Balstad, Trude Rakel; Thorsen, L.; Pripp, AH (Nutrients;Volume 12, Issue 11, Journal article; Peer reviewed, 2020-10-22)
      The aim of this meta-analysis was to examine the effects of nutritional and physical exercise interventions and interventions combining these interventions during radiotherapy treatment for patients with head and neck ...

    • Food intake by Patient-Generated Subjective Global Assessment (PG-SGA) corresponds to energy and protein intake as well as weight change in patients with advanced cancer 

      Bye, Asta; Meli, Kari; Solheim, Tora Skeidsvoll; Laird, Barry J; Kaasa, Stein; Stene, Guro Birgitte; Balstad, Trude Rakel (Clinical Nutrition Experimental; Volume 25, June 2019, Journal article; Peer reviewed, 2019)
      Background & aims The aim of this study was to test how well the Patient-Generated Subjective Global Assessment (PG-SGA) question about food intake correlates with a well-established measurement of food intake. Furthermore, ...

    • Patient interpretation of the Patient-Generated Subjective Global Assessment (PG-SGA) Short Form 

      Balstad, Trude Rakel; Bye, Asta; Jenssen, Cathrine Ragna Solheim; Solheim, Tora Skeidsvoll; Thoresen, Lene; Sand, Kari (Patient Preference and Adherence;Volume 13, Journal article; Peer reviewed, 2019-05-02)
      Background: The Patient-Generated Subjective Global Assessment (PG-SGA) is a patient-reported instrument for assessment of nutrition status in patients with cancer. Despite thorough validation of PG-SGA, little has been ...

    • Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series 

      McDonald, James; Sayers, Judith; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Baracos, Vickie; Brown, Leo; Bye, Asta; Dajani, Olav; Dolan, Ross; Fallon, Marie T.; Fraser, Eilidh; Griel, Christine; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jamal-Hanjani, Mariam; Jakobsen, Gunnhild; Kaasa, Stein; McMillan, Donald; Maddocks, Matthew; Philips, Iain; Ottestad, Inger; Reid, Kieran F.; Sousa, Mariana S.; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Skipworth, Richard J. E.; Solheim, Tora S; Laird, Barry J (Peer reviewed; Journal article, 2023)
      In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, ...

    • Physical rehabilitation in patients with head and neck cancer: Impact on health-related quality of life and suitability of a post-treatment program 

      Sandmæl, Jon Arne; Bye, Asta; Solheim, Tora S; Balstad, Trude Rakel; Thorsen, Lene; Skovlund, Eva; Kaasa, Stein; Lund, Jo-Åsmund; Oldervoll, Line Merethe (Laryngoscope Investigative Otolaryngology;Volume 5, Issue 2, Journal article; Peer reviewed, 2020-03-17)
      Objective: Physical rehabilitation programs hold the potential to mitigate deterioration in health-related quality of life (HRQoL) in patients with head and neck cancer. The objective was to assess development in relevant ...

    • Power comparisons and clinical meaning of outcome measures in assessing treatment effect in cancer cachexia: secondary analysis from a randomised pilot multimodal intervention trial 

      Balstad, Trude Rakel; Brunelli, Cinzia; Pettersen, Caroline Hild; Schønberg, Svanhild Margrethe Arentz; Skorpen, Frank; Fallon, Marie T.; Kaasa, Stein; Bye, Asta; Laird, Barry J. A.; Stene, Guro Birgitte; Solheim, Tora Skeidsvoll (Frontiers in Nutrition; January 2021 | Volume 7 | Article 602775, Journal article; Peer reviewed, 2020-01-14)
      Background: New clinical trials in cancer cachexia are essential, and outcome measures with high responsiveness to detect meaningful changes are crucial. This secondary analysis from a multimodal intervention trial estimates ...

    • A randomized phase II feasibility trial of a multimodal intervention for the management of cachexia in lung and pancreatic cancer 

      Solheim, Tora Skeidsvoll; Laird, Barry J; Balstad, Trude Rakel; Stene, Guro Birgitte; Bye, Asta; Johns, Neil; Pettersen, Caroline Hild Hakvåg; Fallon, Marie; Fayers, Peter; Fearon, Kenneth; Kaasa, Stein (Journal article; Peer reviewed, 2017)
      Background Cancer cachexia is a syndrome of weight loss (including muscle and fat), anorexia, and decreased physical function. It has been suggested that the optimal treatment for cachexia should be a multimodal ...