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dc.contributor.authorKristoffersen, Per M
dc.contributor.authorVetti, Nils
dc.contributor.authorStorheim, Kjersti
dc.contributor.authorBråten, Lars Christian Haugli
dc.contributor.authorRolfsen, Mads Peder
dc.contributor.authorAssmus, Jörg
dc.contributor.authorEspeland, Ansgar
dc.date.accessioned2021-01-29T06:38:25Z
dc.date.accessioned2021-03-05T12:05:57Z
dc.date.available2021-01-29T06:38:25Z
dc.date.available2021-03-05T12:05:57Z
dc.date.issued2020-01-29
dc.identifier.citationKristoffersen PM, Vetti N, Storheim K, Bråten LCH, Rolfsen MP, Assmus J, Espeland A. Short tau inversion recovery MRI of Modic changes: a reliability study. Acta Radiologica Open. 2020;9(1):1-10en
dc.identifier.issn2058-4601
dc.identifier.urihttps://hdl.handle.net/10642/9886
dc.description.abstractBackground: Limited reliability data exist for evaluation of spinal edema changes on magnetic resonance imaging (MRI) with short tau inversion recovery (STIR) sequences. Purpose: To assess the inter-observer reliability for evaluation of STIR signal increase related to Modic changes (MCs) on MRI of the lumbar spine. Material and Methods: We prospectively included 120 patients imaged to confirm their eligibility for the AIM (Antibiotics In Modic changes) trial. Three experienced radiologists independently evaluated MCs on T1-/T2-weighted fast spin-echo images and subsequently MC-related STIR signal increases. Inter-observer reliability was analyzed at four endplates (L4–S1) by calculating kappa values and means of differences with 95% limits of agreement. Results: Overall agreement (mean Fleiss’ kappa for all endplates and observers) was very good for presence of STIR signal increase (0.86), and moderate for its categorized height (0.51), anteroposterior extent (0.48), and volume (0.56). For height of region with STIR signal increase measured in % points of vertebral body height, the largest mean of differences was 6.9 and widest range for limits of agreement was 22.3 for all endplates combined. The corresponding numbers were 11.2 34.5 for anteroposterior extent of the STIR signal increase measured in % points of anteropos- terior endplate diameter and 0.9 7.6 for its maximum measured intensity on a % point scale (0% 1⁄4 normal vertebral marrow intensity, 100% 1⁄4 cerebrospinal fluid intensity). Conclusion: Inter-observer reliability was very good for the presence and intensity of MC-related STIR signal increases, and moderate for their size.en
dc.description.sponsorshipThis work was supported by the South East Norway Regional Health Authority (grant no. 2015-090) and the Western Norway Regional Health Authority (grant nos. HV 911891 and HV 911938).en
dc.language.isoenen
dc.publisherSAGE Publicationsen
dc.relation.ispartofseriesActa Radiologica Open;Volume: 9, issue: 1
dc.rightsCreative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Licenseen
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectSkeletal axesen
dc.subjectMagnetic resonance imagingen
dc.subjectSpinesen
dc.subjectAdultsen
dc.subjectImaging sequencesen
dc.subjectObserver performanceen
dc.titleShort tau inversion recovery MRI of Modic changes: a reliability studyen
dc.typeJournal articleen
dc.typePeer revieweden
dc.date.updated2021-01-29T06:38:24Z
dc.description.versionpublishedVersionen
dc.identifier.doihttps://doi.org/10.1177/2058460120902402
dc.identifier.cristin1881866
dc.source.journalActa Radiologica Open


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Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) License
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