Within-network connectivity in the salience network after attention bias modification training in residual depression: Report from a preregistered clinical trial
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https://hdl.handle.net/10642/6682Utgivelsesdato
2018-12-21Metadata
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Hilland EG, Landrø NI, Harmer C, Maglanoc LA, Jonassen R. Within-network connectivity in the salience network after attention bias modification training in residual depression: Report from a preregistered clinical trial. Frontiers in Human Neuroscience. 2018;12 https://dx.doi.org/10.3389/fnhum.2018.00508Sammendrag
Alterations in resting state networks (RSNs) are associated with emotional- and attentional control difficulties in depressed individuals. Attentional bias modification (ABM) training may lead to more adaptive emotional processing in depression, but little is known about the neural underpinnings associated with ABM. In the current study a sample of 134 previously depressed individuals were randomized into 14 days of computerized ABM- or a closely matched placebo training regime followed by a resting state magnetic resonance imaging (MRI) scan. Using independent component analysis (ICA) we examined within-network connectivity in three major RSN’s, the default mode network (DMN), the salience network (SN) and the central executive network (CEN) after 2 weeks of ABM training. We found a significant difference between the training groups within the SN, but no difference within the DMN or CEN. Moreover, a significant symptom improvement was observed in the ABM group after training.
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Frontiers MediaSerie
Frontiers in Human Neuroscience; December 2018, Volume 12, Article 508Tidsskrift
Frontiers in Human Neuroscience
Med mindre annet er angitt, så er denne innførselen lisensiert som Copyright © 2018 Hilland, Landrø, Harmer, Maglanoc and Jonassen. This is an open-access article Distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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