Suboptimal iodine status among pregnant women in the Oslo area, Norway
Journal article, Peer reviewed
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OriginalversjonHenjum S, Aakre I, Lilleengen AM, Garnweidner-Holme LMG, Borthne S, Pajalic Z, Blix E, Gjengedal EL, Brantsæter AL. Suboptimal iodine status among pregnant women in the Oslo area, Norway. Nutrients. 2018;10(3) http://dx.doi.org/10.3390/nu10030280
Norway has been considered iodine replete for decades; however, recent studies indicate reemergence of inadequate iodine status in different population groups. We assessed iodine status in pregnant women based on urinary iodine concentration (UIC), urinary iodine excretion (UIE), and iodine intake from food and supplements. In 804 pregnant women, 24-h iodine intakes from iodine-rich foods and iodine-containing supplements were calculated. In 777 women, iodine concentration was measured in spot urine samples by inductively coupled plasma/mass spectrometry (ICP-MS). In addition, 49 of the women collected a 24-h urine sample for assessment of UIE and iodine intake from food frequency questionnaire (FFQ). Median UIC was 92 µg/L. Fifty-ﬁve percent had a calculated iodine intake below estimated average requirement (EAR) (160 µg/day). Iodine intake from food alone did not provide the amount of iodine required to meet maternal and fetal needs during pregnancy. In multiple regression models, hypothyroidism, supplemental iodine and maternal age were positively associated with UIC,while gestational age and smoking were negatively associated, explaining 11% of the variance. This study clearly shows that pregnant women in the Oslo area are mild to moderate iodine deﬁcient and public health strategies are needed to improve and secure adequate iodine status.
SerieNutrients;Volume 10, Issue 3
Med mindre annet er angitt, så er denne innførselen lisensiert som © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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