dc.contributor.author | Liodden, Ingrid Elisabeth | en_US |
dc.contributor.author | Sandvik, Leiv | en_US |
dc.contributor.author | Valeberg, Berit Taraldsen | en_US |
dc.contributor.author | Borud, Einar Kristian | en_US |
dc.contributor.author | Norheim, Arne Johan | en_US |
dc.date.accessioned | 2016-02-24T09:48:42Z | |
dc.date.available | 2016-02-24T09:48:42Z | |
dc.date.issued | 2015 | en_US |
dc.identifier.citation | Liodden, I.E., Sandvik, L., Valeberg, B.T., Borud, E.K. & Norheim, A.J. (2015). Acupuncture versus usual care for postoperative nausea and vomiting in children after tonsillectomy/adenoidectomy: a pragmatic, multicenter, double-blinded, randomized trial. Acupuncture in Medicine, 33. doi: 10.1136/acupmed-2014-010738 | en_US |
dc.identifier.issn | 0964-5284 | en_US |
dc.identifier.other | FRIDAID 1237732 | en_US |
dc.identifier.uri | https://hdl.handle.net/10642/3069 | |
dc.description.abstract | Objectives To investigate the effect of a
standardised acupuncture on nausea and
vomiting in children after tonsillectomy with or
without adenoidectomy when possible placebo
effects were precluded.
Methods A pragmatic, multicentre, doubleblinded,
randomised controlled trial. The study
was conducted over 10 months in 2012–2013 at
three ambulatory clinics. Two hundred and
eighty-two children, age 1–11 years, American
Society of Anesthesiologists grade ≤II, were
included. To equalise expectancy effects, all
parents were told that their child would receive
acupuncture. However, children were randomly
allocated to perioperative bilateral needling
acupuncture at PC6, depth 7 mm, mean time
17 min (SD 5–45) during anaesthesia plus usual
care, or to usual care only. The regional ethics
committee approved this approach. Primary
endpoints were nausea and vomiting 24 h
postoperatively.Results This study did not demonstrate any
effect of acupuncture (95% CI) compared with
standard care. The overall vomiting in the
acupuncture and usual-care groups was 44.2%
and 47.9%, respectively. Nausea was
experienced by 31.7% in the acupuncture group
and by 32.6% in the usual-care group. The test
power was acceptable for comparisons of
vomiting.
Conclusions The findings suggest that when
controlling for possible placebo effects
standardised PC6 acupuncture needling during
anaesthesia without further stimulation of PC6 is
not effective in reducing nausea and vomiting in children after tonsillectomy with or without
adenoidectomy. Future studies should investigate
acupuncture treatment which balances adequate
dose and technique and a feasible, child-friendly
acupuncture treatment. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | BMJ Publishing Group | en_US |
dc.relation.ispartofseries | Acupuncture in Medicine;33 | en_US |
dc.subject | Children | en_US |
dc.subject | Acupuncture | en_US |
dc.subject | Postoperative nausea | en_US |
dc.subject | Vomiting | en_US |
dc.subject | Tonsillectomy | en_US |
dc.subject | Adenoidectomy | en_US |
dc.title | Acupuncture versus usual care for postoperative nausea and vomiting in children after tonsillectomy/adenoidectomy: a pragmatic, multicenter, double-blinded, randomized trial | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.identifier.doi | http://dx.doi.org/10.1136/acupmed-2014-010738 | |