Blar i Fakultet for helsevitenskap (HV) på forfatter "Jacobsen, Dag"
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Fatal liver failure after therapeutic doses of paracetamol in a patient with Duchenne muscular dystrophy and atypical pharmacogenetic profile of drug-metabolizing enzymes
Lao, Yvonne Elisabeth; Molden, Espen; Kringen, Marianne K.; Annexstad, Ellen Johanne; Sæverud, Håvard Andreassen; Jacobsen, Dag; Hovda, Knut Erik (Basic & Clinical Pharmacology & Toxicology;Volume 127, Issue 1, July 2020, Journal article; Peer reviewed, 2020-01-24)Paracetamol has a good safety profile, but pharmacogenetic differences in drug-metabolizing enzymes may have an impact on its risk of hepatotoxicity. We present a case of fatal acute liver failure (ALF) after therapeutic ...